公开(公告)号：US11426459B2

公开(公告)日：2022-08-30

申请号：US16756973

申请日：2018-10-10

Applicant: Xiamen University

Inventor： Yixin Chen ,  Chenguang Shen ,  Junyu Chen ,  Mengya Zhang ,  Limin Zhang ,  Ningshao Xia

IPC: A61K39/145 ,  A61K39/00

Abstract: The disclosure relates to a mutant of hemagglutinin protein of H3N2 subtype influenza virus and use thereof. In addition, the disclosure also relates to a pharmaceutical composition (e.g., a vaccine) comprising the mutant, a method for preparing the mutant, and a method of using the mutant for prevention and/or treatment of an infection of influenza virus and/or a disease (e.g., an influenza) caused by the infection.

公开(公告)号：US20210023198A1

公开(公告)日：2021-01-28

申请号：US16756973

申请日：2018-10-10

Applicant: Xiamen University

Inventor： Yixin Chen ,  Chenguang Shen ,  Junyu Chen ,  Mengya Zhang ,  Limin Zhang ,  Ningshao Xia

IPC: A61K39/145

Abstract: The disclosure relates to a mutant of hemagglutinin protein of H3N2 subtype influenza virus and use thereof. In addition, the disclosure also relates to a pharmaceutical composition (e.g., a vaccine) comprising the mutant, a method for preparing the mutant, and a method of using the mutant for prevention and/or treatment of an infection of influenza virus and/or a disease (e.g., an influenza) caused by the infection.