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    System and method for performing probabilistic classification and decision support using multidimensional medical image databases
    1.
    发明授权
    System and method for performing probabilistic classification and decision support using multidimensional medical image databases 有权
    使用多维医学图像数据库执行概率分类和决策支持的系统和方法

    公开(公告)号：US08060178B2

    公开(公告)日：2011-11-15

    申请号：US12243199

    申请日：2008-10-01

    申请人： Xiang Zhou ,  Dorin Comaniciu ,  Alok Gupta ,  Visvanathan Ramesh ,  Bhavani Duggirala ,  Diane Paine

    发明人： Xiang Zhou ,  Dorin Comaniciu ,  Alok Gupta ,  Visvanathan Ramesh ,  Bhavani Duggirala ,  Diane Paine

    IPC分类号： A61B5/00

    CPC分类号： G06K9/6276 ,  A61B8/0883 ,  G06F19/00 ,  G06K9/6256 ,  G06K2209/05 ,  G06Q50/22 ,  G16H50/20 ,  Y10S128/92 ,  Y10S128/924

    摘要： A system and method for providing decision support to a physician during a medical examination is disclosed. Data is received from a sensor representing a particular medical measurement. The received data includes image data. The received data and context data is analyzed with respect to one or more sets of training models. Probability values for the particular medical measurement and other measurements to be taken are derived based on the analysis and based on identified classes. The received image data is compared with training images. Distance values are determined between the received image data and the training images, and the training images are associated with the identified classes. Absolute value feature sensitivity scores are derived for the particular medical measurement and other measurements to be taken based on the analysis. The probability values, distance values and absolute value feature sensitivity scores are outputted to the user.

    摘要翻译： 公开了一种用于在医学检查期间向医师提供决策支持的系统和方法。 从代表特定医疗测量的传感器接收数据。 所接收的数据包括图像数据。 相对于一组或多组训练模型分析接收到的数据和上下文数据。 特定医疗测量和其他测量的概率值基于分析并基于识别的类别导出。 将接收到的图像数据与训练图像进行比较。 在接收的图像数据和训练图像之间确定距离值，并且训练图像与所识别的类别相关联。 基于分析，针对特定医疗测量和其他测量得出绝对值特征灵敏度得分。 将概率值，距离值和绝对值特征灵敏度得分输出给用户。

    Computer aided diagnostic assistance for medical imaging
    2.
    发明授权
    Computer aided diagnostic assistance for medical imaging 有权
    计算机辅助诊断辅助医学成像

    公开(公告)号：US07244230B2

    公开(公告)日：2007-07-17

    申请号：US10702721

    申请日：2003-11-06

    申请人： Bhavani Duggirala ,  Diane S. Paine ,  Dorin Comaniciu ,  Arun Krishnan ,  Xiang Zhou

    发明人： Bhavani Duggirala ,  Diane S. Paine ,  Dorin Comaniciu ,  Arun Krishnan ,  Xiang Zhou

    IPC分类号： A61B5/00 ,  A61B8/00

    CPC分类号： A61B8/56 ,  A61B8/00 ,  A61B8/4427 ,  A61B8/485 ,  A61B8/565 ,  G06F19/00 ,  G06T7/0012 ,  G06T2207/30004 ,  G16H50/20 ,  Y02A90/22 ,  Y02A90/26 ,  Y10S128/925

    摘要： Various attributes for medical CAD analysis used alone or in combination are disclosed, including: (1) using medical sensor data and context information associated with the configuration of the medical system to provide recommendations for further acts to be performed for more accurate or different diagnosis, (2) recommending further acts to be performed and providing an indication of the importance of the further act for further diagnosis, (3) distributing the computer-assisted diagnosis software and/or database over multiple systems, and (4) transmitting patient data to a remote system for CAD diagnosis and using the results of the CAD diagnosis at the remote facility.

    摘要翻译： 公开了用于单独或组合使用的医疗CAD分析的各种属性，包括：（1）使用与医疗系统的配置相关联的医疗传感器数据和上下文信息来提供用于执行更准确或不同诊断的进一步行为的建议， （2）推荐进一步的行为，并提供进一步诊断的进一步行动的重要性的指示，（3）通过多个系统分发计算机辅助诊断软件和/或数据库，以及（4）将患者数据发送到 用于CAD诊断的远程系统，并在远程设施中使用CAD诊断的结果。

    Scalable Semantic Image Search
    4.
    发明申请
    Scalable Semantic Image Search 审中-公开
    可扩展语义图像搜索

    公开(公告)号：US20080027917A1

    公开(公告)日：2008-01-31

    申请号：US11767920

    申请日：2007-06-25

    申请人： Saikat Mukherjee ,  Shaohua Kevin Zhou ,  Xiang Zhou ,  Martin Huber ,  Jorg Freund ,  Volker Tresp ,  Sonja Zillner ,  Alok Gupta ,  Dorin Comaniciu

    发明人： Saikat Mukherjee ,  Shaohua Kevin Zhou ,  Xiang Zhou ,  Martin Huber ,  Jorg Freund ,  Volker Tresp ,  Sonja Zillner ,  Alok Gupta ,  Dorin Comaniciu

    IPC分类号： G06F17/30

    CPC分类号： G06F16/583 ,  G06N5/022

    摘要： A computer-implemented system for searching a plurality of images for an image of interest including a database of semantic image representations corresponding to the plurality of images, wherein the semantic image representations link a semantic model of clinical properties, a syntactic model of high level image properties and an image vocabulary of low level image properties, a set of queries associated with the semantic image representations, and a semantic search engine, embodied as computer readable code executed by a processor, for receiving a search query, selecting at least one of the set of queries based on the search query, and searching the plurality of images for the image of interest by comparing the plurality of images against the semantic image representations associated with a selected query.

    摘要翻译： 一种用于搜索感兴趣的图像的多个图像的计算机实现的系统，包括与多个图像相对应的语义图像表示的数据库，其中所述语义图像表示链接临床属性的语义模型，高级图像的句法模型 低级图像属性的属性和图像词汇表，与语义图像表示相关联的一组查询，以及体现为由处理器执行的计算机可读代码的语义搜索引擎，用于接收搜索查询，选择至少一个 基于搜索查询的查询集合，以及通过将多个图像与与所选择的查询相关联的语义图像表示进行比较来搜索多个图像中的感兴趣图像。

    Systems and methods for automated diagnosis and decision support for heart related diseases and conditions
    5.
    发明申请
    Systems and methods for automated diagnosis and decision support for heart related diseases and conditions 有权
    用于心脏相关疾病和病症的自动诊断和决策支持的系统和方法

    公开(公告)号：US20050020903A1

    公开(公告)日：2005-01-27

    申请号：US10876801

    申请日：2004-06-25

    申请人： Sriram Krishnan ,  Alok Gupta ,  R. Rao ,  Dorin Comaniciu ,  Xiang Zhou

    发明人： Sriram Krishnan ,  Alok Gupta ,  R. Rao ,  Dorin Comaniciu ,  Xiang Zhou

    IPC分类号： A61B5/05 ,  G06F17/00

    CPC分类号： G16H50/20 ,  G06F19/00

    摘要： CAD (computer-aided diagnosis) systems and applications for cardiac imaging are provided, which implement methods to automatically extract and analyze features from a collection of patient information (including image data and/or non-image data) of a subject patient, to provide decision support for various aspects of physician workflow including, for example, automated assessment of regional myocardial function through wall motion analysis, automated diagnosis of heart diseases and conditions such as cardiomyopathy, coronary artery disease and other heart-related medical conditions, and other automated decision support functions. The CAD systems implement machine-learning techniques that use a set of training data obtained (learned) from a database of labeled patient cases in one or more relevant clinical domains and/or expert interpretations of such data to enable the CAD systems to “learn” to analyze patient data and make proper diagnostic assessments and decisions for assisting physician workflow.

    摘要翻译： 提供了用于心脏成像的CAD（计算机辅助诊断）系统和应用，其实现了从受试患者的患者信息（包括图像数据和/或非图像数据）的集合中自动提取和分析特征的方法，以提供 对医师工作流程的各个方面的决策支持，包括例如通过壁运动分析自动评估区域心肌功能，心脏疾病的自动诊断和诸如心肌病，冠状动脉疾病和其他与心脏相关的医疗状况等条件，以及其他自动化决策 支持功能。 CAD系统实施机器学习技术，其使用从一个或多个相关临床领域的标记的患者病例的数据库获得（学习）的一组训练数据和/或对这些数据的专家解释，使得CAD系统能够“学习” 分析患者数据，进行适当的诊断评估和决策，以协助医师的工作流程。

    System and Method For Integrating Heterogeneous Biomedical Information
    6.
    发明申请
    System and Method For Integrating Heterogeneous Biomedical Information 审中-公开
    用于整合异构生物医学信息的系统和方法

    公开(公告)号：US20070130206A1

    公开(公告)日：2007-06-07

    申请号：US11462616

    申请日：2006-08-04

    申请人： Xiang Zhou ,  Dorin Comaniciu ,  Alok Gupta ,  Zhuowen Tu ,  Daniel Fasulo ,  Lu-yong Wang ,  Peiya Liu ,  Saikat Mukherjee ,  Amit Chakraborty

    发明人： Xiang Zhou ,  Dorin Comaniciu ,  Alok Gupta ,  Zhuowen Tu ,  Daniel Fasulo ,  Lu-yong Wang ,  Peiya Liu ,  Saikat Mukherjee ,  Amit Chakraborty

    IPC分类号： G06F17/00

    CPC分类号： G16H50/20 ,  G16H10/60 ,  G16H50/50 ,  G16H50/70

    摘要： A system and method for using heterogeneous data from multiple healthcare information sources in a medical decision support system is disclosed. Each healthcare information system stores medical data using a different local schema. The medical decision support system provides responses to user queries. A query is received from a user that is generated in a standardized global schema. The query includes information from medical ontologies. Database queries are generated from the user queries that use the medical ontologies to generate constraints in the queries. The medical ontologies are also used to infer database queries. The generated query is translated into multiple queries for the multiple healthcare systems wherein each query is in the local schema of the healthcare information system that is being queried. Each database query is transmitted to one of the healthcare information systems based on the local schema of the particular query. Data is collected from each of the queried healthcare information system and analyzed. A query response is formulated for the user

    摘要翻译： 公开了一种在医疗决策支持系统中使用来自多个保健信息源的异构数据的系统和方法。 每个保健信息系统使用不同的本地模式存储医疗数据。 医疗决策支持系统提供对用户查询的响应。 从标准化全局模式中生成的用户接收到查询。 该查询包括医学本体的信息。 数据库查询是从使用医学本体的用户查询生成查询中的约束生成的。 医学本体也用于推断数据库查询。 所生成的查询被转换成多个医疗保健系统的多个查询，其中每个查询在被查询的医疗保健信息系统的本地模式中。 基于特定查询的本地模式，将每个数据库查询发送到医疗保健信息系统之一。 从每个被查询的医疗信息系统收集数据并进行分析。 为用户制定了查询响应

    Method of database-guided segmentation of anatomical structures having complex appearances
    7.
    发明申请
    Method of database-guided segmentation of anatomical structures having complex appearances 有权
    具有复杂外观的解剖结构的数据库引导分割方法

    公开(公告)号：US20060171586A1

    公开(公告)日：2006-08-03

    申请号：US11265772

    申请日：2005-11-02

    申请人： Bogdan Georgescu ,  Xiang Zhou ,  Dorin Comaniciu ,  R. Rao ,  Alok Gupta

    发明人： Bogdan Georgescu ,  Xiang Zhou ,  Dorin Comaniciu ,  R. Rao ,  Alok Gupta

    IPC分类号： G06K9/34 ,  G06K9/00

    CPC分类号： G06K9/6255 ,  G06T7/11 ,  G06T2207/10132 ,  G06T2207/20081 ,  G06T2207/30048 ,  Y10S128/922 ,  Y10S128/923

    摘要： A method for segmenting an anatomical structure of interest within an image is disclosed. The anatomical structure of interest is compared to a database of images of like anatomical structures. Those database images of like anatomical structures that are similar to the anatomical structure of interest are identified. The identified database images are used to detect the anatomical structure of interest in the image. The identified database images are also used to determine the shape of the anatomical structure of interest. The anatomical structure of interest is segmented from the image.

    摘要翻译： 公开了一种用于分割图像内感兴趣的解剖结构的方法。 感兴趣的解剖结构与类似解剖结构的图像的数据库进行比较。 识别与感兴趣的解剖结构相似的类似解剖结构的数据库图像。 识别的数据库图像用于检测图像中感兴趣的解剖结构。 所识别的数据库图像也用于确定感兴趣的解剖结构的形状。 感兴趣的解剖结构从图像中分割。

    Computer aided detection and decision support
    8.
    发明授权
    Computer aided detection and decision support 有权
    计算机辅助检测和决策支持

    公开(公告)号：US08121360B2

    公开(公告)日：2012-02-21

    申请号：US11782694

    申请日：2007-07-25

    申请人： Xiang Zhou ,  Alok Gupta ,  Arun Krishnan ,  Jörg Freund ,  Dorin Comaniciu

    发明人： Xiang Zhou ,  Alok Gupta ,  Arun Krishnan ,  Jörg Freund ,  Dorin Comaniciu

    IPC分类号： G06K9/00

    CPC分类号： G06F17/30247 ,  G06F19/00 ,  G06F19/321 ,  G06T7/0012 ,  G06T2207/30004 ,  G06T2207/30196 ,  G16H50/70

    摘要： A system for computer aided detection and decision support includes an ontology of image representations for injecting meaning into and adding relationships among image contents, an image understanding and parsing module in communication with the ontology of image representations for extracting structures from an image including the image contents, and a reasoning engine based in communication with the ontology and the image understanding and parsing module for classifying the image contents, wherein the system receives the image and corresponding descriptive information.

    摘要翻译： 一种用于计算机辅助检测和决策支持的系统包括用于将意图注入并添加图像内容之间的关系的图像表示本体，与图像表示本体通信的图像理解和解析模块，用于从包括图像内容的图像提取结构 以及与本体通信的推理引擎和用于对图像内容进行分类的图像理解和解析模块，其中系统接收图像和对应的描述信息。

    Computer Aided Detection and Decision Support
    10.
    发明申请
    Computer Aided Detection and Decision Support 有权
    计算机辅助检测与决策支持

    公开(公告)号：US20080037852A1

    公开(公告)日：2008-02-14

    申请号：US11782694

    申请日：2007-07-25

    申请人： Xiang Zhou ,  Alok Gupta ,  Arun Krishnan ,  Jorg Freund ,  Dorin Comaniciu

    发明人： Xiang Zhou ,  Alok Gupta ,  Arun Krishnan ,  Jorg Freund ,  Dorin Comaniciu

    IPC分类号： G06K9/00

    CPC分类号： G06F17/30247 ,  G06F19/00 ,  G06F19/321 ,  G06T7/0012 ,  G06T2207/30004 ,  G06T2207/30196 ,  G16H50/70

    摘要： A system for computer aided detection and decision support includes an ontology of image representations for injecting meaning into and adding relationships among image contents, an image understanding and parsing module in communication with the ontology of image representations for extracting structures from an image including the image contents, and a reasoning engine based in communication with the ontology and the image understanding and parsing module for classifying the image contents, wherein the system receives the image and corresponding descriptive information.

    摘要翻译： 一种用于计算机辅助检测和决策支持的系统包括用于将意图注入并添加图像内容之间的关系的图像表示本体，与图像表示本体通信的图像理解和解析模块，用于从包括图像内容的图像提取结构 以及与本体通信的推理引擎和用于对图像内容进行分类的图像理解和解析模块，其中系统接收图像和对应的描述信息。