公开(公告)号：US08544602B2

公开(公告)日：2013-10-01

申请号：US13310411

申请日：2011-12-02

申请人： Xiaoyang Xu ,  Xiuqin Gao

发明人： Xiaoyang Xu ,  Xiuqin Gao

IPC分类号： A62B35/00 ,  B66F11/00

CPC分类号： B61K13/00 ,  A62B35/0056

摘要： A safety protection device for the roof construction of a train body assembly comprises two arch bridge shaped transverse walking boards and a safety rope, wherein the safety rope is fixed between the span of the two arch bridge shaped transverse walking boards. The invention has the following benefit effects: the safety for the worker walking and working on the roof can be guaranteed since the worker walks up to the roof through the arch bridge shaped transverse walking boards and ties the other end of a safety belt which is tied on him to the safety rope.

摘要翻译： 一种用于火车车身组件屋顶结构的安全保护装置，包括两个拱形桥形横向步行板和一根安全绳，其中安全绳固定在两个拱桥横向行走板的跨距之间。 本发明具有以下效果：工人在屋顶上行走和工作的安全性可以得到保证，因为工人通过拱形桥形横向步行板走向屋顶，并将绑扎的安全带的另一端 对他安全绳。

公开(公告)号：US20090145742A1

公开(公告)日：2009-06-11

申请号：US12331928

申请日：2008-12-10

申请人： Chad A. Mirkin ,  Wei Wei ,  Lidong Qin ,  Can Xue ,  Jill E. Millstone ,  Xiaoyang Xu

发明人： Chad A. Mirkin ,  Wei Wei ,  Lidong Qin ,  Can Xue ,  Jill E. Millstone ,  Xiaoyang Xu

IPC分类号： B01J19/12 ,  G21G5/00

CPC分类号： B01J35/004 ,  B01J23/42 ,  B01J23/48 ,  B01J23/50 ,  B01J23/52 ,  B01J35/06 ,  B82Y20/00 ,  B82Y30/00 ,  B82Y40/00 ,  C01B3/042 ,  Y02E60/364 ,  Y02P20/134

摘要： Disclosed herein is energy transfer on multisegmented nanowires via surface plasmon resonance excitation of visible light, such as solar energy, absorbed by metals sensitive to visible light and transferred to metals insensitive to visible light. The nanowires are prepared with controllable gap sizes between different segments by on-wire lithography (OWL).

摘要翻译： 本文公开的是通过对可见光的表面等离子体共振激发（例如由对可见光敏感的金属吸收的太阳能）转移到对可见光不敏感的金属的多分段纳米线的能量转移。 通过在线光刻（OWL）在不同的片段之间制备具有可控的间隙尺寸的纳米线。

公开(公告)号：US09073181B2

公开(公告)日：2015-07-07

申请号：US13699036

申请日：2011-07-12

申请人： Xiaoyang Xu

发明人： Xiaoyang Xu

IPC分类号： B25B1/00 ,  B25B1/20 ,  B25B1/02 ,  B25B5/14 ,  B23K37/04 ,  B25B5/00

CPC分类号： B25B5/14 ,  B23K37/0443 ,  B25B5/006

摘要： The utility model provides a combined positioning device for a side beam of a stainless steel car roof, comprising an inner cavity positioning block (2), an external support body (3), an external positioning block (4), a push rod (5), and clamps (6), a top side of the inner cavity positioning block (2) fits in with a top inner portion of the side beam (7) of the car roof, the external support body (3) is adjustably connected to a surface of the inner cavity positioning block (2), the external positioning block (4) is adjustably connected to a surface of the external support body (3), an elongated nut of the push rod (5) is integrated with the inner cavity positioning block (2), and the clamps (6) are used to clamp two edges of the side beam (7) of the car roof. With the present utility model, the side beam of the car roof can be supported by fitting the inner cavity positioning block in with the top inner portion of the side beam of the car roof, and sizes such as width and height can be adjusted through adjustments of the external support body connected to the inner cavity positioning block, the external positioning block and the clamps.

摘要翻译： 本实用新型提供了一种用于不锈钢车顶的侧梁的组合定位装置，包括内腔定位块（2），外支撑体（3），外定位块（4），推杆（5） ）和夹具（6），内腔定位块（2）的顶侧与轿厢顶板的侧梁（7）的顶部内部部分配合，外部支撑体（3）可调节地连接到 所述内腔定位块（2）的表面，所述外定位块（4）可调节地连接到所述外支撑体（3）的表面，所述推杆（5）的细长螺母与所述内腔 定位块（2）和夹具（6）用于夹紧车顶的侧梁（7）的两个边缘。 利用本实用新型，车顶的侧梁可以通过将内腔定位块与轿厢顶梁的侧梁的顶部内部部分配合来支撑，并且可以通过调节来调节诸如宽度和高度的尺寸 外部支撑体连接到内腔定位块，外部定位块和夹具。

公开(公告)号：US20130134643A1

公开(公告)日：2013-05-30

申请号：US13699036

申请日：2011-07-12

申请人： Xiaoyang Xu

发明人： Xiaoyang Xu

IPC分类号： B25B5/14

CPC分类号： B25B5/14 ,  B23K37/0443 ,  B25B5/006

摘要： The utility model provides a combined positioning device for a side beam of a stainless steel car roof, comprising an inner cavity positioning block (2), an external support body (3), an external positioning block (4), a push rod (5), and clamps (6), a top side of the inner cavity positioning block (2) fits in with a top inner portion of the side beam (7) of the car roof, the external support body (3) is adjustably connected to a surface of the inner cavity positioning block (2), the external positioning block (4) is adjustably connected to a surface of the external support body (3), an elongated nut of the push rod (5) is integrated with the inner cavity positioning block (2), and the clamps (6) are used to clamp two edges of the side beam (7) of the car roof. With the present utility model, the side beam of the car roof can be supported by fitting the inner cavity positioning block in with the top inner portion of the side beam of the car roof, and sizes such as width and height can be adjusted through adjustments of the external support body connected to the inner cavity positioning is block, the external positioning block and the clamps.

摘要翻译： 本实用新型提供了一种用于不锈钢车顶的侧梁的组合定位装置，包括内腔定位块（2），外支撑体（3），外定位块（4），推杆（5） ）和夹具（6），内腔定位块（2）的顶侧与轿厢顶板的侧梁（7）的顶部内部部分配合，外部支撑体（3）可调节地连接到 所述内腔定位块（2）的表面，所述外定位块（4）可调节地连接到所述外支撑体（3）的表面，所述推杆（5）的细长螺母与所述内腔 定位块（2）和夹具（6）用于夹紧车顶的侧梁（7）的两个边缘。 利用本实用新型，车顶的侧梁可以通过将内腔定位块与轿厢顶梁的侧梁的顶部内部部分配合来支撑，并且可以通过调节来调整诸如宽度和高度的尺寸 外部支撑体连接到内腔的定位是块体，外部定位块和夹具。

公开(公告)号：US09636730B2

公开(公告)日：2017-05-02

申请号：US13701101

申请日：2011-07-12

申请人： Xiaoyang Xu ,  Ting Wang

发明人： Xiaoyang Xu ,  Ting Wang

IPC分类号： B21D1/12 ,  B21D1/14

CPC分类号： B21D1/12 ,  B21D1/14

摘要： The utility model provides an apparatus for correcting upwarp deformation of a large member of a stainless steel car roof, being characterized in that, it has a crossbeam, end support columns, a middle support column, an arc-shaped positioning body, crossbeam pull rings, a thin steel taut strap, and tighteners. The end support columns, crossbeam, and middle support column constitute a supporting part, the arc-shaped positioning body having the same arc shape as an inner arc of the large member of the stainless steel car roof is arranged on the middle support column. The thin steel taut strap covers an exterior contour surface of the large member of the stainless steel car roof, and is connected via the tightener to the crossbeam pull rings respectively fixed at two ends of the crossbeam.

公开(公告)号：US20120269730A1

公开(公告)日：2012-10-25

申请号：US13388629

申请日：2010-08-09

申请人： Chad A. Mirkin ,  Thomas J. Meade ,  Ying Song ,  Xiaoyang Xu

发明人： Chad A. Mirkin ,  Thomas J. Meade ,  Ying Song ,  Xiaoyang Xu

IPC分类号： C07H21/04 ,  C12Q1/02 ,  A61K49/00 ,  B82Y15/00

CPC分类号： A61K49/128 ,  A61K49/0002 ,  A61K49/1881

摘要： The present invention is directed to compositions and methods for intracellular delivery of a contrast agent with a functionalized nanoparticle.

摘要翻译： 本发明涉及用官能化纳米颗粒细胞内递送造影剂的组合物和方法。

公开(公告)号：US20130133393A1

公开(公告)日：2013-05-30

申请号：US13701101

申请日：2011-07-12

申请人： Xiaoyang Xu ,  Ting Wang

发明人： Xiaoyang Xu ,  Ting Wang

IPC分类号： B21D1/12

CPC分类号： B21D1/12 ,  B21D1/14

摘要： The utility model provides an apparatus for correcting upwarp deformation of a large member (11) of a stainless steel car roof, being characterized in that, comprising a crossbeam (1), end support columns (2), a middle support column (3), an arc-shaped positioning body (5), crossbeam pull rings (7), a thin steel taut strap (8), and tighteners (9), the end support columns (2), the crossbeam (1), and the middle support column (3) constitute a supporting part, the arc-shaped positioning body having the same arc shape as an inner arc of the large member of the stainless steel car roof is arranged on the middle support column (3), the thin steel taut strap (8) covers an exterior contour surface of the large member (11) of the stainless steel car roof, and is connected via the tightener (9) to the crossbeam pull rings (7) respectively fixed at two ends of the crossbeam (1). The apparatus can solve the problem of upwarp deformation of the large member of the stainless steel car roof, and restore the arc shape of the car roof and the car width.

摘要翻译： 本实用新型提供了一种用于校正不锈钢车顶的大件（11）的上翘变形的装置，其特征在于，包括横梁（1），端支柱（2），中支撑柱（3） ，弧形定位体（5），横梁拉环（7），薄钢拉紧带（8）和紧固件（9），端部支撑柱（2），横梁（1）和中间 支撑柱（3）构成支撑部件，具有与不锈钢车顶的大部件的内弧相同的弧形的弧形定位体布置在中间支撑柱（3）上，薄钢拉紧 带（8）覆盖不锈钢车顶的大件（11）的外轮廓表面，并通过紧固器（9）连接到分别固定在横梁（1）两端的横梁拉环（7） ）。 该装置可以解决不锈钢车顶大件件上翘变形的问题，恢复车顶的弧形和车宽。

公开(公告)号：US20090280188A1

公开(公告)日：2009-11-12

申请号：US12302465

申请日：2007-06-25

申请人： Chad A. Mirkin ,  Fengwei Huo ,  Abigail K.R. Lytton-Jean ,  Xiaoyang Xu ,  Nathaniel L. Rosi ,  Yuhuang Wang

发明人： Chad A. Mirkin ,  Fengwei Huo ,  Abigail K.R. Lytton-Jean ,  Xiaoyang Xu ,  Nathaniel L. Rosi ,  Yuhuang Wang

IPC分类号： A61K9/14 ,  A61K31/7088

CPC分类号： C12Q1/6834 ,  C12Q2563/155 ,  C12Q2521/501

摘要： Disclosed herein are asymmetrically functionalized nanoparticles. Further disclosed herein are methods of preparing asymmetrically functionalized nanoparticles. Asymmetrically functionalized nanoparticles can be used in various therapeutic methods.

摘要翻译： 本文公开了不对称官能化的纳米颗粒。 本文进一步公开的是制备不对称官能化纳米颗粒的方法。 不对称官能化的纳米颗粒可用于各种治疗方法。

公开(公告)号：US20090155785A1

公开(公告)日：2009-06-18

申请号：US12020506

申请日：2008-01-25

申请人： Chad A. Mirkin ,  Xiaoyang Xu ,  Min Su Han

发明人： Chad A. Mirkin ,  Xiaoyang Xu ,  Min Su Han

IPC分类号： C12Q1/68

CPC分类号： G01N33/553 ,  B82Y5/00 ,  C12Q1/34 ,  G01N33/587

摘要： The invention provides methods for screening a compound for its effect on endonuclease activity. The methods comprise providing a compound to be screened utilizing a gold nanoparticle aggregate as the substrate for the endonuclease. The gold nanoparticle aggregate is formed by the hybridization of oligonucleotides attached to the nanoparticles, with or without the presence of a third linker oligonucleotide. The hybridized oligonucleotide duplex serves as a substrate for the endonuclease. A detectable change is brought about in the presence of the endonuclease activity. A decrease in the detectable change reflects the reduced levels of endonuclease activities as a result of the effects of endonuclease inhibitors. The present invention also provides kits for screening an endonuclease inhibitor.

摘要翻译： 本发明提供了筛选化合物对其对核酸内切酶活性的影响的方法。 所述方法包括使用金纳米颗粒聚集体作为内切核酸酶的底物提供待筛选的化合物。 金纳米颗粒聚集体通过与或不与第三接头寡核苷酸的存在连接到纳米颗粒上的寡核苷酸的杂交形成。 杂交的寡核苷酸双链体用作内切核酸酶的底物。 在存在核酸内切酶活性的情况下可以发现可检测的变化。 可检测变化的降低反映了由于内切核酸酶抑制剂的作用而导致的内切核酸酶活性的降低。 本发明还提供了用于筛选内切核酸酶抑制剂的试剂盒。

公开(公告)号：US20200054003A1

公开(公告)日：2020-02-20

申请号：US16487154

申请日：2017-02-24

申请人： Xiaoyang Xu

发明人： Xiaoyang Xu

IPC分类号： A01N1/02

摘要： A cell freeze-drying system, comprising: a temperature-elevated nitrogen supplier, a freeze-drying operation box, and a gas discharger, which are connected in that order using a first connection pipe. The temperature-elevated nitrogen supplier supplies warmed nitrogen to the freeze-drying operation box. A cell sample frozen by liquid nitrogen is placed in the freeze-drying operation box, and then the freeze-drying operation box, which is preset to a temperature suitable for placing the cell sample frozen by liquid nitrogen, is warmed up in a preset mode while continuously being supplied with the warmed nitrogen to sublimate solid state water in the cell sample into gaseous water. The gas discharger is used to discharge the gaseous nitrogen and the gaseous water. Further disclosed is a cell freeze-drying method. The invention can effectively address an issue of cell damage and contamination during freeze-drying, and realizes safety, efficiency, and low costs for cell freeze-drying.