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公开(公告)号：US08557199B2
公开(公告)日：2013-10-15
申请号：US12629749
申请日：2009-12-02
申请人： James Heath , Lidong Qin
发明人： James Heath , Lidong Qin
CPC分类号： F04B19/006 , B01J23/42 , B01J23/50 , B01L3/50273 , B01L2300/0636 , B01L2300/0816 , B01L2300/14 , B01L2400/046
摘要： A power source for actuation of a microfluidic device and related devices, methods and systems.
摘要翻译： 用于致动微流体装置和相关装置，方法和系统的电源。
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公开(公告)号：US20100140171A1
公开(公告)日：2010-06-10
申请号：US12629749
申请日：2009-12-02
申请人： James HEATH , Lidong Qin
发明人： James HEATH , Lidong Qin
CPC分类号： F04B19/006 , B01J23/42 , B01J23/50 , B01L3/50273 , B01L2300/0636 , B01L2300/0816 , B01L2300/14 , B01L2400/046
摘要： A power source for actuation of a microfluidic device and related devices, methods and systems.
摘要翻译： 用于致动微流体装置和相关装置，方法和系统的电源。
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公开(公告)号：US20180071737A1
公开(公告)日：2018-03-15
申请号：US15822072
申请日：2017-11-24
申请人： Lidong Qin
发明人： Lidong Qin , Kai Zhang
摘要： According to the invention, generally, a method for making a microfluidic aliquoting (MA) chip, adapted to fit in a Petri dish, has a center well (inlet) connected by branched channels to a plurality of side wells (outlets). The chip comes in various types, including a bMA Chip T1, bMA Chip T2, bMA Chip T3, and an rMA Chip. The branched channel improvement provides for a greater distance between neighboring channels and a decreased density near the center well. Design improvements including an injection mold design for an insert and a base and a multiplex hole punch allow for rapid fabrication of the MA chip.
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公开(公告)号：US20180015471A1
公开(公告)日：2018-01-18
申请号：US15701401
申请日：2017-09-11
申请人： Lidong Qin , Kai Zhang
发明人： Lidong Qin , Kai Zhang
CPC分类号： B01L3/502761 , B01L3/5023 , B01L3/5027 , B01L2200/0652 , B01L2200/0668 , B01L2200/10 , B01L2300/021 , B01L2300/0803 , B01L2300/0806 , B01L2300/0864 , B01L2300/0893 , B01L2300/123 , B01L2400/0457 , B01L2400/0487 , C12Q1/04
摘要： According to the invention, generally, a microfluidic aliquoting (MA) chip, adapted to fit in a Petri dish, has a center well (inlet) connected by branched channels to a plurality of side wells (outlets). The chip comes in various types, including a bMA Chip T1, bMA Chip T2, bMA Chip T3, and an rMA Chip. The branched channel improvement provides for a greater distance between neighboring channels and a decreased density near the center well. Design improvements including an injection mold design for an insert and a base and a multiplex hole punch allow for rapid fabrication of the MA chip.
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公开(公告)号：US20090155587A1
公开(公告)日：2009-06-18
申请号：US12196960
申请日：2008-08-22
申请人： Chad A. Mirkin , Lidong Qin , Sungho Park , Ling Huang , Sung-Wook Chung
发明人： Chad A. Mirkin , Lidong Qin , Sungho Park , Ling Huang , Sung-Wook Chung
CPC分类号： H01C17/06513 , B82Y5/00 , B82Y10/00 , B82Y20/00 , G01N33/531 , H01L29/0665 , H01L29/0673 , H01L29/068 , H01L29/861 , Y10S977/762 , Y10S977/81 , Y10S977/849 , Y10S977/856 , Y10S977/857 , Y10T428/2938 , Y10T428/2982
摘要： Multicomponent nanorods having segments with differing electronic and/or chemical properties are disclosed. The nanorods can be tailored with high precision to create controlled gaps within the nanorods or to produce diodes or resistors, based upon the identities of the components making up the segments of the nanorods. Macrostructural composites of these nanorods also are disclosed.
摘要翻译： 公开了具有不同电子和/或化学性质的多组分纳米棒。 纳米棒可以以高精度进行定制，以在纳米棒内产生可控制的间隙，或者基于组成纳米棒段的部件的特性来产生二极管或电阻器。 还公开了这些纳米棒的宏观结构复合材料。
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公开(公告)号：US20080225287A1
公开(公告)日：2008-09-18
申请号：US11372583
申请日：2006-03-10
申请人： Chad A. Mirkin , Lidong Qin , Can Xue , Sungho Park , Ling Huang
发明人： Chad A. Mirkin , Lidong Qin , Can Xue , Sungho Park , Ling Huang
IPC分类号： G01J3/44
CPC分类号： G01J3/44 , B82Y15/00 , G01N21/658 , Y10S977/762
摘要： The present invention relates to methods of detecting analytes using nanowires having nanodisk arrays. In particular, the present invention discloses methods of detecting analytes via surface enhanced Raman scattering (SERS) and employing nanowires prepared using on-wire lithography (OWL).
摘要翻译： 本发明涉及使用具有纳米盘阵列的纳米线检测分析物的方法。 特别地，本发明公开了通过表面增强拉曼散射（SERS）检测分析物并使用在线光刻（OWL）制备的纳米线的方法。
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公开(公告)号：US11413619B1
公开(公告)日：2022-08-16
申请号：US16932225
申请日：2020-07-17
申请人： Lidong Qin
发明人： Lidong Qin , Kai Zhang , Joon Hee Jang , Myeong Chan Jo
IPC分类号： B01L3/00
摘要： A multi-well plate comprising: inlet wells configured to contain liquid; walled observation windows located between the inlet wells, each observation window being associated with a respective inlet well; detection wells, each being disposed below a respective observation window and being associated with the respective inlet well associated with the respective observation window; outlet wells located between the inlet wells and the observation windows, each outlet well being associated with a respective inlet well and a respective detection well; inlet channels, disposed in first groups, each first group providing fluid communication between an inlet well and a respective detection well; outlet channels, disposed in second groups, each second group providing fluid communication between a detection well and a respective outlet well. The inlet channels are configured to prevent passage of the liquid from the inlet wells to the respective detection wells if no external force is applied to the liquid.
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8.发明申请ENERGY TRANSFER THROUGH SURFACE PLASMON RESONANCE EXCITATION ON MULTISEGMENTED NANOWIRES 审中-公开通过表面等离子体共振激发在多种纳米级纳米粒子上的能量转移公开(公告)号：US20120006674A1
公开(公告)日：2012-01-12
申请号：US13037942
申请日：2011-03-01
申请人： Chad A. Mirkin , Wei Wei , Lidong Qin , Can Xue , Jill E. Millstone , Xiaoyang Xu
发明人： Chad A. Mirkin , Wei Wei , Lidong Qin , Can Xue , Jill E. Millstone , Xiaoyang Xu
IPC分类号： C01B21/36 , C01B13/00 , C07D301/03 , C01B31/18 , C01B31/20
CPC分类号： B01J35/004 , B01J23/42 , B01J23/48 , B01J23/50 , B01J23/52 , B01J35/06 , B82Y20/00 , B82Y30/00 , B82Y40/00 , C01B3/042 , Y02E60/364 , Y02P20/134
摘要： Disclosed herein is energy transfer on multisegmented nanowires via surface plasmon resonance excitation of visible light, such as solar energy, absorbed by metals sensitive to visible light and transferred to metals insensitive to visible light. The nanowires are prepared with controllable gap sizes between different segments by on-wire lithography (OWL).
摘要翻译： 本文公开的是通过对可见光的表面等离子体共振激发（例如由对可见光敏感的金属吸收的太阳能）转移到对可见光不敏感的金属的多分段纳米线的能量转移。 通过在线光刻（OWL）在不同的片段之间制备具有可控的间隙尺寸的纳米线。
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9.发明申请ELECTRICAL NANOTRAPS FOR SPECTROSCOPICALLY CHARACTERIZING BIOMOLECULES WITHIN 审中-公开用于光谱学表征生物分子的电子纳米粒子公开(公告)号：US20090166222A1
公开(公告)日：2009-07-02
申请号：US12206057
申请日：2008-09-08
申请人： Chad A. Mirkin , Gengfeng Zheng , Lidong Qin
发明人： Chad A. Mirkin , Gengfeng Zheng , Lidong Qin
CPC分类号： G01N21/658 , B82Y15/00 , G01N21/6428 , G01N33/54346
摘要： A method that combines on-wire-lithography (OWL) nanogaps, an electric field concentrating technique, and surface enhanced Raman spectroscopy (SERS) is disclosed for sensitive detection of analytes with small sample sizes in a chip format.
摘要翻译： 公开了一种组合在线光刻（OWL）纳米片，电场浓缩技术和表面增强拉曼光谱（SERS）的方法，用于以芯片格式的小样品尺寸的分析物的敏感检测。
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公开(公告)号：US07466406B2
公开(公告)日：2008-12-16
申请号：US11372583
申请日：2006-03-10
申请人： Chad A. Mirkin , Lidong Qin , Can Xue , Sungho Park , Ling Huang
发明人： Chad A. Mirkin , Lidong Qin , Can Xue , Sungho Park , Ling Huang
IPC分类号： G01J3/44
CPC分类号： G01J3/44 , B82Y15/00 , G01N21/658 , Y10S977/762
摘要： The present invention relates to methods of detecting analytes using nanowires having nanodisk arrays. In particular, the present invention discloses methods of detecting analytes via surface enhanced Raman scattering (SERS) and employing nanowires prepared using on-wire lithography (OWL).
摘要翻译： 本发明涉及使用具有纳米盘阵列的纳米线检测分析物的方法。 特别地，本发明公开了通过表面增强拉曼散射（SERS）检测分析物并使用在线光刻（OWL）制备的纳米线的方法。
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