公开(公告)号：US07271298B2

公开(公告)日：2007-09-18

申请号：US11336869

申请日：2006-01-23

申请人： Xinde Xu ,  Bin Shao ,  Di Zhou ,  Shuangming Ye ,  Yanfeng Wang ,  Boqiu Chen

发明人： Xinde Xu ,  Bin Shao ,  Di Zhou ,  Shuangming Ye ,  Yanfeng Wang ,  Boqiu Chen

IPC分类号： C07C35/21

CPC分类号： C07C403/24

摘要： A process for isolation and purification of xanthophylls crystals from plant oleoresin is disclosed. The organic solvents involved in the process is no other than food grade alcohol. The process includes saponifying the plant oleoresin containing xanthophyll diesters, neutralizing the saponified reaction mixture with an acid and washing water-soluble impurities and other fat-soluble oil with warm water and alcohol, respectively. The process can improve purity and yield of products, by which the content and the recovery of xanthophylls are as high as 90% and 80% respectively. And the process is economical and easy to perform in industrial production.

摘要翻译： 公开了从植物油树脂中分离和纯化叶黄素晶体的方法。 涉及该方法的有机溶剂不是食品级酒精。 该方法包括皂化含有叶黄素二酯的植物油树脂，用酸中和皂化反应混合物，并分别用温水和酒精洗涤水溶性杂质和其他脂溶性油。 该方法可以提高产品的纯度和产量，其中叶黄素的含量和回收率分别高达90％和80％。 该工艺在工业生产中经济实惠。

公开(公告)号：US20070032683A1

公开(公告)日：2007-02-08

申请号：US11336869

申请日：2006-01-23

申请人： Xinde Xu ,  Bin Shao ,  Di Zhou ,  Shuangming Ye ,  Yanfeng Wang ,  Boqiu Chen

发明人： Xinde Xu ,  Bin Shao ,  Di Zhou ,  Shuangming Ye ,  Yanfeng Wang ,  Boqiu Chen

IPC分类号： C07C35/21 ,  C07C35/06

CPC分类号： C07C403/24

摘要： A process for isolation and purification of xanthophylls crystals from plant oleoresin is disclosed. The organic solvents involved in the process is no other than food grade alcohol. The process includes saponifying the plant oleoresin containing xanthophyll diesters, neutralizing the saponified reaction mixture with an acid and washing water-soluble impurities and other fat-soluble oil with warm water and alcohol, respectively. The process can improve purity and yield of products, by which the content and the recovery of xanthophylls are as high as 90% and 80% respectively. And the process is economical and easy to perform in industrial production.

公开(公告)号：US20080081932A1

公开(公告)日：2008-04-03

申请号：US11857248

申请日：2007-09-18

申请人： Xinde Xu ,  Lihua Zhang ,  Boqiu Chen ,  Di Zhou ,  Shuangming Ye ,  Chiyu Ding ,  Hongping Lv ,  Bin Shao

发明人： Xinde Xu ,  Lihua Zhang ,  Boqiu Chen ,  Di Zhou ,  Shuangming Ye ,  Chiyu Ding ,  Hongping Lv ,  Bin Shao

IPC分类号： C07C35/21

CPC分类号： C07C403/24 ,  A23L5/44 ,  A23L33/10 ,  C07C2601/16 ,  C09B61/00 ,  C09B67/0025 ,  C09B67/0096

摘要： This invention has disclosed a method for preparation of food-grade zeaxanthin through chemical isomerizaton reaction from lutein. The technical issues to be solved in this invention are quite low product yield obtained with existing methods, need of purification treatment process, and inadaptability to industrialized production. The technical schemes of this invention are: a. Mix xanthophyll crystal or its fatty acid ester with food-grade glycol or propylene glycol, for full dissolution under 60-90° C. temperature. Add organic alkali into the mixed liquor acquired from step 1, for isomerization reaction to take place under inertial environment. c. Dilute the reaction solution gained from step b with the mixed solution of deionized water and ethanol, and separate the obtained crystal with conventional separating method. d. Vacuum dries the acquired crystal from step c, to get the zeaxanthin crystal. Glycol or propylene glycol is used in this invention for isomerization reaction under inertial environment after it has fully dissolved raw material under proper temperature. The product yield is reachable to more than 60%, very adaptable to industrialized product, without the need for further purification treatment.

摘要翻译： 本发明公开了通过叶黄素化学异构化反应制备食品级玉米黄质的方法。 本发明要解决的技术问题是用现有方法获得的产品产率相当低，需要净化处理工艺，以及对工业化生产的适应性。 本发明的技术方案是：a。 将叶黄素晶体或其脂肪酸酯与食品级二醇或丙二醇混合，在60-90℃的温度下完全溶解。 将有机碱添加到从步骤1获得的混合液中，以在惯性环境下进行异构化反应。 C。 用去离子水和乙醇的混合溶液稀释从步骤b获得的反应溶液，并用常规分离方法分离得到的晶体。 d。 真空干燥步骤c获得的晶体，得到玉米黄质晶体。 乙二醇或丙二醇在本发明中在适当温度下完全溶解原料之后，在惯性环境下用于异构化反应。 产品产量可达60％以上，非常适用于工业化产品，无需进一步净化处理。

公开(公告)号：US07485738B2

公开(公告)日：2009-02-03

申请号：US11857248

申请日：2007-09-18

申请人： Xinde Xu ,  Lihua Zhang ,  Boqiu Chen ,  Di Zhou ,  Shuangming Ye ,  Chiyu Ding ,  Hongping Lv ,  Bin Shao

发明人： Xinde Xu ,  Lihua Zhang ,  Boqiu Chen ,  Di Zhou ,  Shuangming Ye ,  Chiyu Ding ,  Hongping Lv ,  Bin Shao

IPC分类号： C07C51/353

CPC分类号： C07C403/24 ,  A23L5/44 ,  A23L33/10 ,  C07C2601/16 ,  C09B61/00 ,  C09B67/0025 ,  C09B67/0096

摘要： This invention has disclosed a method for preparation of food-grade zeaxanthin through chemical isomerizaton reaction from lutein. The technical issues to be solved in this invention are quite low product yield obtained with existing methods, need of purification treatment process, and inadaptability to industrialized production. The technical schemes of this invention are: a. Mix xanthophyll crystal or its fatty acid ester with food-grade glycol or propylene glycol, for full dissolution under 60-90° C. temperature. Add organic alkali into the mixed liquor acquired from step 1, for isomerization reaction to take place under inertial environment. c. Dilute the reaction solution gained from step b with the mixed solution of deionized water and ethanol, and separate the obtained crystal with conventional separating method. d. Vacuum dries the acquired crystal from step c, to get the zeaxanthin crystal. Glycol or propylene glycol is used in this invention for isomerization reaction under inertial environment after it has fully dissolved raw material under proper temperature. The product yield is reachable to more than 60%, very adaptable to industrialized product, without the need for further purification treatment.

摘要翻译： 本发明公开了通过叶黄素化学异构化反应制备食品级玉米黄质的方法。 本发明要解决的技术问题是用现有方法获得的产品产率相当低，需要净化处理工艺，以及对工业化生产的适应性。 本发明的技术方案是：a。 将叶黄素晶体或其脂肪酸酯与食品级二醇或丙二醇混合，在60-90℃的温度下完全溶解。 将有机碱添加到从步骤1获得的混合液中，以在惯性环境下进行异构化反应。 C。 用去离子水和乙醇的混合溶液稀释从步骤b获得的反应溶液，并用常规分离方法分离得到的晶体。 d。 真空干燥步骤c获得的晶体，得到玉米黄质晶体。 乙二醇或丙二醇在本发明中在适当温度下完全溶解原料之后，在惯性环境下用于异构化反应。 产品产量可达60％以上，非常适用于工业化产品，无需进一步净化处理。