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公开(公告)号:US20170281700A1
公开(公告)日:2017-10-05
申请号:US15623556
申请日:2017-06-15
申请人: YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM LTD. , HADASIT MEDICAL RESEARCH SERVICES & DEVELOPMENT LTD.
发明人: Nissan Ronen HAZAN , Nurit BEYTH
CPC分类号: A61K35/76 , A61K9/0034 , A61K45/06 , C12N7/00 , C12N2795/10121 , C12N2795/10132 , C12N2795/10171
摘要: Isolated bacteriophages having genomes comprising the nucleic acid sequences as set forth in SEQ ID NOs: 1 and 2, or variants thereof, and compositions comprising the bacteriophages in a ratio ranging from 1:10 to 10:1, respectively. Further provided are uses of the compositions in treating or preventing an infection inflicted by a bacteria (e.g., Enterococcous faecalis and/or Enterococcous faecium). As a non-limiting example, the composition may be used in treating or preventing a root canal infection.