摘要:
An organic compound of formula E is made from a process comprising:reacting a compound of formula A and a compound of formula B to form a compound of formula C; and reacting one of the compound of formula C and the compound of formula D with a first boron esterification reagent to generate a boronic acid or a boronic ester to react with another of the compound of formula C and the compound of formula D to form a compound of formula E; wherein R1, R2, and R3 are, independently at each occurrence, a C1-C20 aliphatic radical, a C3-C20 aromatic radical, or a C3-C20 cycloaliphatic radical;X1 is chloro, bromo, trifluoromethanesulfonate, or hydroxy;X2 is chloro, bromo, iodo; and when X1 is chloro, X2 is bromo or iodo, when X1 is bromo, X2 is iodo, when X1 is hydroxy, X2 is chloro, bromo or iodo, when X1 is trifluoromethanesulfonate, X2 is bromo or iodo;X3 is a boronic acid or boronic ester;X is CH or N and when X is CH, at least one of R2 is pyridyl;X4 is chloro, bromo, trifluoromethanesulfonate, or hydroxy;X5 is chloro, bromo, iodo; and when X4 is chloro, X5 is bromo or iodo, when X4 is bromo, X5 is iodo, when X4 is hydroxy, X5 is chloro, bromo or iodo, when X4 is trifluoromethanesulfonate, X5 is bromo or iodo;a, and c are, independently at each occurrence, an integer ranging from 0-4; and b is an integer ranging from 0-3.
摘要:
A compound of formula II is prepared by: reacting a compound of formula F with 1-chloro-3,5-dibromobenzene to form a compound of formula G; reacting the compound of formula C with pinacol diborane to form a compound of formula H; reacting the compound of formula H with 1-bromo-3-iodobenzene to form a compound of formula J; and reacting the compound of formula J with pinacol diborane to form a compound of formula K; and reacting the compound of formula K with 3,5-dibromopyridine to form the compound of formula II.
摘要:
An organic compound of formula E is made from a process comprising: reacting a compound of formula A and a compound of formula B to form a compound of formula C; and reacting one of the compound of formula C and the compound of formula D with a first boron esterification reagent to generate a boronic acid or a boronic ester to react with another of the compound of formula C and the compound of formula D to form a compound of formula E; wherein R1, R2, and R3 are, independently at each occurrence, a C1-C20 aliphatic radical, a C3-C20 aromatic radical, or a C3-C20 cycloaliphatic radical.
摘要:
Compound of formula C is made by reacting a compound of formula A with an pyridyl boronic acid or pyridyl borate ester to form a compound of formula B; and combining the compound of formula B with a pyridyl dihalide to form the compound of C; wherein R3, R4, R5, R6 and R7 are, independently at each occurrence, a C1-C20 aliphatic radical, a C3-C20 aromatic radical, or a C3-C20 cycloaliphatic radical; X is, independently at each occurrence, CH or N; Y is chloro or bromo; Z is bromo or iodo; and when Y is bromo, Z is iodo; d, e, and g are, independently at each occurrence, an integer ranging from 0-4; f is an integer ranging from 0-2; and h is an integer ranging from 0-3.
摘要:
Compound of formula C is made by reacting a compound of formula A with an pyridyl boronic acid or pyridyl borate ester to form a compound of formula B; and combining the compound of formula B with a pyridyl dihalide to form the compound of C; wherein R3, R4, R5, R6 and R7 are, independently at each occurrence, a C1-C20 aliphatic radical, a C3-C20 aromatic radical, or a C3-C20 cycloaliphatic radical; X is, independently at each occurrence, CH or N; Y is chloro or bromo; Z is bromo or iodo; and when Y is bromo, Z is iodo; d, e, and g are, independently at each occurrence, an integer ranging from 0-4; f is an integer ranging from 0-2; and h is an integer ranging from 0-3.
摘要:
A compound of formula II is prepared by: reacting a compound of formula F with 1-chloro-3,5-dibromobenzene to form a compound of formula G; reacting the compound of formula G with pinacol diborane to form a compound of formula H; reacting the compound of formula H with 1-bromo-3-iodobenzene to form a compound of formula J.
摘要:
An arithmetic logic unit (ALU) includes a front end latch stage coupled to a signal latch stage coupled to a Gray code (GC) to binary stage. First inputs of an adder stage are coupled to receive outputs of the GC to binary stage. Outputs of the adder stage are generated in response to the first inputs and second inputs of the adder stage. A pre-latch stage is coupled to latch outputs of the adder stage. A feedback latch stage is coupled to latch outputs of the pre-latch stage. The second inputs of the adder stage are coupled to receive outputs of the feedback latch stage. The feedback stage includes first conversion gain feedback latches configured to latch outputs of the pre-latch stage having a first conversion gain and second conversion gain feedback latches configured to latch outputs of the pre-latch stage having a second conversion gain.
摘要:
The disclosed embodiments describe a method, apparatus, and system for pushing information. In one embodiment, the method comprises: receiving dynamic spatio-temporal behavior data of a moving individual; conducting an analysis according to historical dynamic spatio-temporal behavior data of the moving individual to acquire spatio-temporal behavioral characteristics of the moving individual; determining appropriate information as matching information for the moving individual according to the spatio-temporal behavioral characteristics of the moving individual in combination with dynamic spatio-temporal behavior data of the moving individual at a current time; and sending the matching information to the moving individual. In the method of the disclosure, behavioral characteristics of a moving individual are analyzed to obtain habit and preference characteristics of the moving individual. Targeted push information is sent, thereby solving the problem of pushed information having less diversified, targeted, and not so accurate content.
摘要:
Provided is a method applied to a system including a plurality of sensors, a proxy, and a server. The method includes: measuring objects by the plurality of sensors to obtain first measurement values; computing a correlation among the first measurement values by the server based on the first measurement values; computing an actual measurement value of a second measurement value by the proxy based on the first measurement values and a given function; verifying the plurality of sensors by setting one or more sensors as verification target sensors in turn by the server at predetermined timing; computing a predicted value of the second measurement value by the server based on the correlation and the first measurement values obtained from the other sensors; and outputting the predicted value of the second measurement value instead of the actual measurement value thereof at least during the verification of the verification target sensors.