Compound 2-amino-3-[2-(&agr;-mannopyranosyl)indol-3-yl]propionic acid, process for preparing the same, and method for inspecting function of living body with the novel compound
    3.
    发明授权
    Compound 2-amino-3-[2-(&agr;-mannopyranosyl)indol-3-yl]propionic acid, process for preparing the same, and method for inspecting function of living body with the novel compound 有权
    化合物2-氨基-3- [2-(α-甘露吡喃糖基)吲哚-3-基]丙酸,其制备方法以及用新化合物检测活体功能的方法

    公开(公告)号:US06610502B1

    公开(公告)日:2003-08-26

    申请号:US09486115

    申请日:2000-02-18

    IPC分类号: G01N33577

    摘要: The present invention relates to a novel endogenous compound 2-amino-3-[2-(&agr;-mannopyranosyl)indole-3-yl]propionic acid; to a method for testing a biological function by quantitating 2-amino-3-[2-(&agr;-mannopyranosyl)indole-3-yl]propionic acid in a collected biological sample and determining the biological function based on the quantitated values; to an antibody specifically reactive with 2-amino-3-[2-(&agr;-mannopyranosyl)indole-3-yl]propionic acid; to a hybridoma that produces the antibody; to a method for immunologically quantitating 2-amino-3-[2-(&agr;-mannopyranosyl)indole-3-yl]propionic acid in a sample by using the antibody; and to a process for producing a 2-amino-3-[2-(&agr;-mannopyranosyl)indole-3-yl]propionic acid derivative.

    摘要翻译: 本发明涉及新的内源化合物2-氨基-3- [2-(α-甘桂吡喃糖基)吲哚-3-基]丙酸; 涉及通过在收集的生物样品中定量2-氨基-3- [2-(α-甘露吡喃糖基)吲哚-3-基]丙酸来测定生物学功能的方法,并基于定量值确定生物学功能; 与2-氨基-3- [2-(α-甘露吡喃糖基)吲哚-3-基]丙酸特异性反应的抗体; 产生抗体的杂交瘤; 涉及通过使用抗体免疫定量样品中2-氨基-3- [2-(α-甘露吡喃糖基)吲哚-3-基]丙酸的方法; 以及2-氨基-3- [2-(α-甘露吡喃糖基)吲哚-3-基]丙酸衍生物的制备方法。