公开(公告)号：US5360415A

公开(公告)日：1994-11-01

申请号：US804362

申请日：1991-12-10

申请人： Yasunori Yabushita ,  Hiroshi Yokoi ,  Masanao Koyama ,  Munehiro Takatsuka

发明人： Yasunori Yabushita ,  Hiroshi Yokoi ,  Masanao Koyama ,  Munehiro Takatsuka

IPC分类号： A61L29/00 ,  A61L29/08 ,  A61L29/14 ,  A61M25/00

CPC分类号： A61L29/145 ,  A61L29/085 ,  A61M25/0017

摘要： An anti-infective catheter on which a layer of a water absorbing polymer is formed. Since the layer of the water absorbing polymer swells by absorbing body fluid in subcutaneous tissue, space between the inserted catheter and its peripheral skin moiety is filled quickly, thus preventing penetration of pathogens in the living body along the wall of the catheter. The anti-infective catheter of the present invention can be inserted in the living body easily without forming a site for the arrangement of a cuff and can prevent penetration of pathogens immediately after its insertion without affecting peripheral tissue.

摘要翻译： 一种抗感染导管，其上形成有吸水聚合物层。 由于吸水性聚合物层通过吸收皮下组织中的体液而膨胀，所以插入的导管与其周边皮肤部分之间的空间被快速填充，从而防止病原体沿导管的壁渗透。 本发明的抗感染导管可以容易地插入生物体中，而不形成用于袖带布置的部位，并且可以防止病原体插入后立即渗透而不影响外周组织。

公开(公告)号：US5584882A

公开(公告)日：1996-12-17

申请号：US486582

申请日：1995-06-07

申请人： Yasunori Yabushita ,  Munehiro Takatsuka ,  Shinichi Sakai

发明人： Yasunori Yabushita ,  Munehiro Takatsuka ,  Shinichi Sakai

IPC分类号： A61F2/16 ,  A61L33/00

CPC分类号： A61L33/0047 ,  A61F2/16 ,  A61L33/0041

摘要： The antithrombotic intraocular lens of the present invention carries a fibrinolytic substance conjugatedly immobilized on its surface and, as such, lyses insoluble proteins such as fibrin deposited on the lens surface from the blood and exudate after implantation to fully retain its lens function. Furthermore, the present invention inhibits adhesion of the lens to the surrounding tissues and contributes to accelerated recovery after operation. The present invention further provides a simple method for immobilizing a fibrinolytic substance by conjugation on the surface of a variety of lens materials including silicones. Moreover, because the fibrinolytic substance is immobilized only to the surface of the lens material, the dynamic and optical properties of the intraocular lens are not adversely affected.

摘要翻译： 本发明的抗血栓性眼内晶状体携带在其表面共轭固定的纤维蛋白溶解物质，因此在植入后溶解沉积在透镜表面上的不溶性蛋白质如血液和渗出物，以完全保留其透镜功能。 此外，本发明抑制透镜对周围组织的粘附，并且有助于操作后的加速恢复。 本发明还提供了通过共轭将纤维蛋白溶解物质固定在包括硅氧烷的各种透镜材料的表面上的简单方法。 此外，由于纤维蛋白溶解物质仅固定在镜片材料的表面，因此眼内透镜的动态和光学特性不会受到不利影响。