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公开(公告)号:US08835411B2
公开(公告)日:2014-09-16
申请号:US13312483
申请日:2011-12-06
申请人: Yasutsuga Ueda , Timothy P. Connolly , Barry L. Johnson , Chen Li , B. Narasimhulu Naidu , Manoj Patel , Kevin Peese , Margaret E. Sorenson , Michael A. Walker , Michael S. Bowsher , Rongti Li
发明人: Yasutsuga Ueda , Timothy P. Connolly , Barry L. Johnson , Chen Li , B. Narasimhulu Naidu , Manoj Patel , Kevin Peese , Margaret E. Sorenson , Michael A. Walker , Michael S. Bowsher , Rongti Li
IPC分类号: C07D519/00 , C07D487/08
CPC分类号: C07D487/08 , C07D519/00
摘要: The disclosure generally relates to the novel compounds of formula I, including their salts, which inhibit HIV integrase and prevent viral integration into human DNA. This action makes the compounds useful for treating HIV infection and AIDS. The invention also encompasses pharmaceutical compositions and methods for treating those infected with HIV.
摘要翻译: 本公开一般涉及式I的新化合物,包括其盐,其抑制HIV整合酶并防止病毒整合入人DNA。 这种作用使这些化合物可用于治疗艾滋病毒和艾滋病。 本发明还包括用于治疗感染HIV的那些的药物组合物和方法。