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公开(公告)号：US20100080771A1
公开(公告)日：2010-04-01
申请号：US12566441
申请日：2009-09-24
IPC分类号： A61K38/20 , A61K38/21 , A61P31/12 , A61K31/7088 , A61K31/407 , C07D498/08
CPC分类号： C07D498/18
摘要： Hepatitis C virus inhibitors having the general formula are disclosed. Compositions comprising the compounds and methods for using the compounds to inhibit HCV are also disclosed.
摘要翻译： 公开了具有通式的丙型肝炎病毒抑制剂。 还公开了包含化合物的组合物和使用该化合物抑制HCV的方法。
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公开(公告)号：US08563505B2
公开(公告)日：2013-10-22
申请号：US12566441
申请日：2009-09-24
CPC分类号： C07D498/18
摘要： Hepatitis C virus inhibitors having the general formula are disclosed. Compositions comprising the compounds and methods for using the compounds to inhibit HCV are also disclosed.
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公开(公告)号：US20120309698A1
公开(公告)日：2012-12-06
申请号：US13312483
申请日：2011-12-06
申请人： Yasutsugu Ueda , Timothy P. Connolly , Barry L. Johnson , Chen Li , B. Narasimhulu Naidu , Manoj Patel , Kevin Peese , Margaret E. Sorenson , Michael A. Walker , Michael S. Bowsher , Rongti Li
发明人： Yasutsugu Ueda , Timothy P. Connolly , Barry L. Johnson , Chen Li , B. Narasimhulu Naidu , Manoj Patel , Kevin Peese , Margaret E. Sorenson , Michael A. Walker , Michael S. Bowsher , Rongti Li
IPC分类号： A61K31/55 , A61K31/655 , A61K31/553 , A61P31/18 , A61K31/7028 , C07J43/00 , A61K31/58 , C07D487/08 , C07H15/26
CPC分类号： C07D487/08 , C07D519/00
摘要： The disclosure generally relates to the novel compounds of formula I, including their salts, which inhibit HIV integrase and prevent viral integration into human DNA. This action makes the compounds useful for treating HIV infection and AIDS. The invention also encompasses pharmaceutical compositions and methods for treating those infected with HIV.
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公开(公告)号：US08957203B2
公开(公告)日：2015-02-17
申请号：US13459403
申请日：2012-04-30
申请人： Sheldon Hiebert , Ramkumar Rajamani , Li-Qiang Sun , Eric Mull , Eric P. Gillis , Michael S. Bowsher , Qian Zhao , Nicholas A. Meanwell , Kishore V. Renduchintala , Kandhasamy Sarkunam , Pulicharla Nagalakshmi , P. V. K. Suresh Babu , Paul Michael Scola
发明人： Sheldon Hiebert , Ramkumar Rajamani , Li-Qiang Sun , Eric Mull , Eric P. Gillis , Michael S. Bowsher , Qian Zhao , Nicholas A. Meanwell , Kishore V. Renduchintala , Kandhasamy Sarkunam , Pulicharla Nagalakshmi , P. V. K. Suresh Babu , Paul Michael Scola
IPC分类号： C07D225/00 , C07D295/00 , C07D245/00 , C07D225/04 , C07D487/00 , C07D487/04 , C07K5/083 , C07K5/08 , A61K38/20 , A61K38/21 , A61K45/06 , A61K31/13 , A61K31/4745 , A61K31/7056 , A61K38/00
CPC分类号： C07K5/0823 , A61K31/13 , A61K31/4745 , A61K31/7056 , A61K38/00 , A61K38/06 , A61K38/2013 , A61K38/204 , A61K38/2053 , A61K38/21 , A61K38/212 , A61K45/06 , C07D487/04 , C07K5/0804 , C07K5/0827 , A61K2300/00
摘要： Hepatitis C virus inhibitors having the general formula (I) are disclosed. Compositions comprising the compounds and methods for using the compounds to inhibit HCV are also disclosed.
摘要翻译： 公开了具有通式（I）的丙型肝炎病毒抑制剂。 还公开了包含化合物的组合物和使用该化合物抑制HCV的方法。
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公开(公告)号：US20100080770A1
公开(公告)日：2010-04-01
申请号：US12559179
申请日：2009-09-14
IPC分类号： A61K38/20 , A61K38/21 , A61K38/46 , A61K38/16 , A61K31/7088 , A61K31/407 , C07D498/08
CPC分类号： C07D498/08 , C07K5/0808 , C07K5/0821
摘要： Hepatitis C virus inhibitors having the general formula are disclosed. Compositions comprising the compounds and methods for using the compounds to inhibit HCV are also disclosed.
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公开(公告)号：US08835411B2
公开(公告)日：2014-09-16
申请号：US13312483
申请日：2011-12-06
申请人： Yasutsuga Ueda , Timothy P. Connolly , Barry L. Johnson , Chen Li , B. Narasimhulu Naidu , Manoj Patel , Kevin Peese , Margaret E. Sorenson , Michael A. Walker , Michael S. Bowsher , Rongti Li
发明人： Yasutsuga Ueda , Timothy P. Connolly , Barry L. Johnson , Chen Li , B. Narasimhulu Naidu , Manoj Patel , Kevin Peese , Margaret E. Sorenson , Michael A. Walker , Michael S. Bowsher , Rongti Li
IPC分类号： C07D519/00 , C07D487/08
CPC分类号： C07D487/08 , C07D519/00
摘要： The disclosure generally relates to the novel compounds of formula I, including their salts, which inhibit HIV integrase and prevent viral integration into human DNA. This action makes the compounds useful for treating HIV infection and AIDS. The invention also encompasses pharmaceutical compositions and methods for treating those infected with HIV.
摘要翻译： 本公开一般涉及式I的新化合物，包括其盐，其抑制HIV整合酶并防止病毒整合入人DNA。 这种作用使这些化合物可用于治疗艾滋病毒和艾滋病。 本发明还包括用于治疗感染HIV的那些的药物组合物和方法。
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公开(公告)号：US20130115190A1
公开(公告)日：2013-05-09
申请号：US13459403
申请日：2012-04-30
申请人： Sheldon Hiebert , Ramkumar Rajamani , Li-Qiang Sun , Eric Mull , Eric P. Gillis , Michael S. Bowsher , Qian Zhao , Nicholas A. Meanwell , Kishore V. Renduchintala , Kandhasamy Sarkunam , Pulicharla Nagalakshmi , P. V. K. Suresh Babu , Paul Michael Scola
发明人： Sheldon Hiebert , Ramkumar Rajamani , Li-Qiang Sun , Eric Mull , Eric P. Gillis , Michael S. Bowsher , Qian Zhao , Nicholas A. Meanwell , Kishore V. Renduchintala , Kandhasamy Sarkunam , Pulicharla Nagalakshmi , P. V. K. Suresh Babu , Paul Michael Scola
CPC分类号： C07K5/0823 , A61K31/13 , A61K31/4745 , A61K31/7056 , A61K38/00 , A61K38/06 , A61K38/2013 , A61K38/204 , A61K38/2053 , A61K38/21 , A61K38/212 , A61K45/06 , C07D487/04 , C07K5/0804 , C07K5/0827 , A61K2300/00
摘要： Hepatitis C virus inhibitors having the general formula (I) are disclosed. Compositions comprising the compounds and methods for using the compounds to inhibit HCV are also disclosed.
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