公开(公告)号：US20090258345A1

公开(公告)日：2009-10-15

申请号：US11576650

申请日：2006-02-25

申请人： Yeon-Su Lee ,  Sang-Hoon Kim ,  Choon-Ryoul Shin ,  Kyung-Hee Park

发明人： Yeon-Su Lee ,  Sang-Hoon Kim ,  Choon-Ryoul Shin ,  Kyung-Hee Park

IPC分类号： C12Q1/68 ,  C07K14/00 ,  G01N33/68 ,  C12Q1/02 ,  C12N15/11 ,  C40B40/08

CPC分类号： C07K14/4748 ,  G01N33/57419

摘要： Provided are an isolated nucleolar protein having an amino acid sequence of NCBI GenBank Accession No. XP_033371, a method of diagnosing colorectal cancer in an individual, including measuring an expression level of a protein having an amino acid sequence of NCBI GenBank Accession No. XP_033371 in the individual, and a polynucleotide for diagnosis or treatment of colorectal cancer including at least 10 contiguous nucleotides of a nucleotide sequence selected from the group consisting of nucleotide sequences of SEQ ID NOS: 1-5 and including a nucleotide at position 101 of the nucleotide sequence, or a complementary polynucleotide thereof.

摘要翻译： 提供了具有NCBI GenBank登录号XP_033371的氨基酸序列的分离的核仁蛋白，其是个体中诊断结肠直肠癌的方法，包括测定具有NCBI GenBank登录号XP_033371的氨基酸序列的蛋白质的表达水平在 个体和用于诊断或治疗结肠直肠癌的多核苷酸，包括选自SEQ ID NO：1-5的核苷酸序列的核苷酸序列的至少10个连续核苷酸，并且包含核苷酸序列的101位的核苷酸 ，或其互补多核苷酸。