公开(公告)号：US20090018485A1

公开(公告)日：2009-01-15

申请号：US12211295

申请日：2008-09-16

申请人： Yosef KRESPI ,  Ashutosh KACKER

发明人： Yosef KRESPI ,  Ashutosh KACKER

IPC分类号： A61N5/06

CPC分类号： A61N5/062 ,  A61B18/18 ,  A61B18/1815 ,  A61N5/0601 ,  A61N5/0624 ,  A61N2005/0606 ,  A61N2005/0607 ,  A61N2005/0644 ,  A61N2005/0654

摘要： Disclosed are methods and apparatus for safe, simple and effective broad-spectrum treatments of chronic rhinosinusitis and other common and less common infections of the sino-nasal tract which may implicate not only a wide range of bacterial species but also fungi and viruses. Electromagnetic radiative energy including visible, and optionally, thermal RF, microwave or other longer wavelengths, is applied to target internal surfaces of the sino-nasal tract to destroy or incapacitate superficial microorganisms without the use of antibiotics. The treatment can be controlled to permit regrowth of healthy microflora. A handheld energy applicator has a light output head receivable into, or engageable with, the treatment subject's nostril which may be provided with extensions to reach the sinuses. Useful embodiments of the invention include pretreatment of target sino-nasal surfaces with a photosensitizing agent such as an oxidizing agent or a complementary stain. For example methylene blue can be used with orange or red light. The combination treatment of photosensitizer and application of visual wavelength energy provides a flexible treatment regimen which enables low concentrations of stains to be employed, minimizing aesthetic problems.

摘要翻译： 公开了用于安全，简单和有效地广泛治疗慢性鼻鼻窦炎和其他常见且不太常见的中鼻道感染的方法和装置，其可能不仅涉及广泛的细菌种类，而且也可能涉及真菌和病毒。 将包括可见光和可选的RF，微波或其他较长波长的电磁辐射能量施加到中鼻道的目标内表面，以破坏或消除表面微生物而不使用抗生素。 可以控制治疗以允许健康微生物群落的再生长。 手持式能量施加器具有可以接收到治疗对象的鼻孔中或与受治疗者的鼻孔接合的光输出头，其可以设置有延伸部以达到鼻窦。 本发明的有用实施方案包括用光敏剂如氧化剂或互补染色剂预处理靶鼻鼻表面。 例如亚甲基蓝可以与橙色或红色的光一起使用。 光敏剂的组合治疗和视觉波长能量的应用提供了灵活的治疗方案，其使得能够使用低浓度的污渍，从而最小化审美问题。