公开(公告)号：US06617569B2

公开(公告)日：2003-09-09

申请号：US09860643

申请日：2001-05-21

申请人： Yoshihito Narita ,  Tsutomu Inoue ,  Susumu Teruyama ,  Toshiharu Saiki ,  Shuji Mononobe ,  Motoichi Ohtsu

发明人： Yoshihito Narita ,  Tsutomu Inoue ,  Susumu Teruyama ,  Toshiharu Saiki ,  Shuji Mononobe ,  Motoichi Ohtsu

IPC分类号： H01J516

CPC分类号： G01Q60/22

摘要： A probe opening forming apparatus 139 comprising: light detecting means 140 for detecting a quantity of a light transmitted from a tip portion of the probe through a light of the source 116, which is on contact with the tip portion of the probe; storage means 142 for previously storing information about relation of the quantity of the light transmitted from the tip portion of the probe and the size of the opening; calculating means 144 for obtaining the value of the light quantity for obtaining an opening having a desirable size based on the information stored in the storage means 142; and pressing control means 126 for controlling the press of the tip portion of the probe against the light detecting means through the pressing means 114 such that a light quantity detected by the light detecting means 140 is equal to the light quantity calculated from the calculating means 144.

摘要翻译： 探针开口形成装置139，包括：光检测装置140，用于通过与探针的尖端部分接触的源116的光来检测从探针的末端部分透射的光量; 存储装置142，用于预先存储关于从探头的尖端部分传播的光量与开口尺寸的关系的信息; 计算装置144，用于基于存储在存储装置142中的信息获得用于获得具有期望尺寸的开口的光量的值; 以及按压控制装置126，用于通过按压装置114控制探针的顶端部分对光检测装置的按压，使得由光检测装置140检测的光量等于从计算装置144计算的光量 。

公开(公告)号：US06803558B2

公开(公告)日：2004-10-12

申请号：US10796089

申请日：2004-03-10

申请人： Tsutomu Inoue ,  Fuminori Sato ,  Yoshihito Narita

发明人： Tsutomu Inoue ,  Fuminori Sato ,  Yoshihito Narita

IPC分类号： H01J4014

CPC分类号： G01Q60/22

摘要： An opening fabricating apparatus for creating an opening with desired dimensions at a mask tip of a near-field optical microscope, and a near-field optical microscope using the same are provided. The apparatus comprising: a light source 116; reflection means 140; light detection means 124; press means 128, 130 pressing a probe tip against said reflection means; storage means 142; calculation means 144 figuring out the quantity of light of the reflected light for the acquisition of said opening with desired dimensions from the calibration information stored in said storage means; and press control means 126 controlling pressing of said probe tip against said reflection means so as to allow the quantity of light of said reflected light to become equal to the quantity figured out by said calculation means. The probe opening fabricating apparatus is capable of readily fabricating an opening of desired dimensions with a high reproducibility.

公开(公告)号：US20060238758A1

公开(公告)日：2006-10-26

申请号：US11398096

申请日：2006-04-05

申请人： Tsutomu Inoue ,  Fuminori Sato ,  Yoshihito Narita ,  Mutsumi Senuma

发明人： Tsutomu Inoue ,  Fuminori Sato ,  Yoshihito Narita ,  Mutsumi Senuma

IPC分类号： G01J4/00

CPC分类号： G01J4/00 ,  G01N21/21 ,  G01Q30/02 ,  G01Q60/22

摘要： A near-field polarized-light measurement apparatus 10 comprises a near-field probe 14, an analyzer 18, a detector 22, and an analyzer-rotating unit 20. The near-field probe 14 has at a tip thereof an opening smaller than the wavelength of light used for measurement and generates linearly polarized near-field light from the opening and irradiates a sample with the near-field light. The detector 22 detects light transmitted through the sample via the analyzer 18. The analyzer-rotating unit 20 rotates the analyzer 18 about an optical axis to vary the angle of a transmission axis thereof. And optical rotation of the sample is measured by rotating the analyzer 18 with the analyzer-rotating unit 20.

摘要翻译： 近场偏振光测量装置10包括近场探针14，分析器18，检测器22和分析仪旋转单元20。 近场探头14在其前端处具有小于用于测量的光的波长的开口，并且从该开口产生线偏振的近场光，并用近场光照射样本。 检测器22通过分析器18检测透过样品的光。 分析器旋转单元20使分析器18围绕光轴旋转，以改变其透射轴的角度。 通过用分析器旋转单元20旋转分析器18来测量样品的旋光度。

公开(公告)号：US06812449B2

公开(公告)日：2004-11-02

申请号：US10796088

申请日：2004-03-10

申请人： Tsutomu Inoue ,  Fuminori Sato ,  Yoshihito Narita

发明人： Tsutomu Inoue ,  Fuminori Sato ,  Yoshihito Narita

IPC分类号： H01J4014

CPC分类号： G01Q60/22

摘要： An opening fabricating apparatus for creating an opening with desired dimensions at a mask tip of a near-field optical microscope, and a near-field optical microscope using the same are provided. The apparatus comprising: a light source 116; reflection means 140, light detection means 124; press means 128, 130 pressing a probe tip against said reflection means; storage means 142; calculation means 144 figuring out the quantity of light of the reflected light for the acquisition of said opening with desired dimensions from the calibration information stored in said storage means; and press control means 126 controlling pressing of said probe tip against said reflection means so as to allow the quantity of light of said reflected light to become equal to the quantity figured out by said calculation means. The probe opening fabricating apparatus is capable of readily fabricating an opening of desired dimensions with a high reproducibility.

摘要翻译： 提供了一种用于在近场光学显微镜的掩模尖端处产生具有期望尺寸的开口的开口制造装置和使用其的近场光学显微镜。 该装置包括：光源116; 反射装置140，光检测装置124; 按压装置128,130将探针尖端压靠在所述反射装置上; 存储装置142; 计算装置144根据存储在所述存储装置中的校准信息计算用于从所述开口获取所需开口的反射光的光量; 以及按压控制装置126，控制所述探头尖靠在所述反射装置上，以便使所述反射光的光量等于由所述计算装置计算出的量。 探头开口制造装置能够以高再现性容易地制造所需尺寸的开口。

公开(公告)号：US06784414B2

公开(公告)日：2004-08-31

申请号：US10208749

申请日：2002-08-01

申请人： Tsutomu Inoue ,  Fuminori Sato ,  Yoshihito Narita

发明人： Tsutomu Inoue ,  Fuminori Sato ,  Yoshihito Narita

IPC分类号： H01J4014

CPC分类号： G01Q60/22

摘要： An opening fabricating apparatus for creating an opening with desired dimensions at a mask tip of a near-field optical microscope, and a near-field optical microscope using the same are provided. The apparatus comprising: a light source 116; reflection means 140; light detection means 124; press means 128, 130 pressing a probe tip against said reflection means; storage means 142; calculation means 144 figuring out the quantity of light of the reflected light for the acquisition of said opening with desired dimensions from the calibration information stored in said storage means; and press control means 126 controlling pressing of said probe tip against said reflection means so as to allow the quantity of light of said reflected light to become equal to the quantity figured out by said calculation means. The probe opening fabricating apparatus is capable of readily fabricating an opening of desired dimensions with a high reproducibility.

公开(公告)号：US07586606B2

公开(公告)日：2009-09-08

申请号：US11398096

申请日：2006-04-05

申请人： Tsutomu Inoue ,  Fuminori Sato ,  Yoshihito Narita ,  Mutsumi Senuma

发明人： Tsutomu Inoue ,  Fuminori Sato ,  Yoshihito Narita ,  Mutsumi Senuma

IPC分类号： G01J4/00

CPC分类号： G01J4/00 ,  G01N21/21 ,  G01Q30/02 ,  G01Q60/22

摘要： A near-field polarized-light measurement apparatus 10 comprises a near-field probe 14, an analyzer 18, a detector 22, and an analyzer-rotating unit 20. The near-field probe 14 has at a tip thereof an opening smaller than the wavelength of light used for measurement and generates linearly polarized near-field light from the opening and irradiates a sample with the near-field light. The detector 22 detects light transmitted through the sample via the analyzer 18. The analyzer-rotating unit 20 rotates the analyzer 18 about an optical axis to vary the angle of a transmission axis thereof. And optical rotation of the sample is measured by rotating the analyzer 18 with the analyzer-rotating unit 20.

摘要翻译： 近场偏振光测量装置10包括近场探针14，分析器18，检测器22和分析器旋转单元20.近场探针14的尖端处具有小于 用于测量的光的波长，并从该开口产生线偏振的近场光，并用近场光照射样本。 检测器22通过分析器18检测透过样品的光。分析器旋转单元20使分析器18围绕光轴旋转，以改变其透射轴的角度。 通过用分析器旋转单元20旋转分析器18来测量样品的旋光度。

公开(公告)号：US06813402B2

公开(公告)日：2004-11-02

申请号：US10076302

申请日：2002-02-19

申请人： Yoshihito Narita ,  Tsutomu Inoue

发明人： Yoshihito Narita ,  Tsutomu Inoue

IPC分类号： G02B612

CPC分类号： G01Q60/22 ,  G02B6/241 ,  G02B6/245 ,  Y10S977/862

摘要： It is an object of the present invention to provide a probe that may correspond to various styles of measurement when used in microscopes and that is also applicable to recording devices and an optical head using the same, as well as to provide a method for manufacturing such a probe in a simple and costless manner; for achieving such objects, the method for manufacturing a multiple optical path array type probe according to the present invention is arranged in that in a light guiding material including a substrate that functions as a clad and a light guiding path formed of a component that functions as a core for guiding light or as a waveguide, the light guiding material includes a plurality of light guiding paths aligned to be parallel to each other within the substrate that functions as a clad, and tip end portions of the light guiding paths are sharpened through chemical etching of an end surface that is orthogonal to the plurality of light guiding paths.

摘要翻译： 本发明的目的是提供一种探针，其可以对应于在显微镜中使用时的各种测量方式，并且也可应用于记录装置和使用其的光学头，以及提供用于制造这样的方法 以简单而无成本的方式进行探索; 为了实现这些目的，根据本发明的多光路阵列型探针的制造方法的特征在于，在具有作为包层的基板的导光材料和由作为包层的部件形成的导光路径 用于引导光或作为波导的芯，所述导光材料包括在所述基板内彼此平行排列的多个导光路径，所述导光路径用作包层，并且所述导光路径的末端部分通过化学 蚀刻与多个导光路径正交的端面。

公开(公告)号：US06777656B2

公开(公告)日：2004-08-17

申请号：US10238627

申请日：2002-09-11

申请人： Yoshihito Narita ,  Fuminori Sato ,  Tohru Sakamaki ,  Tsutomu Inoue ,  Shigeyuki Kimura ,  Norihito Hujiwara

发明人： Yoshihito Narita ,  Fuminori Sato ,  Tohru Sakamaki ,  Tsutomu Inoue ,  Shigeyuki Kimura ,  Norihito Hujiwara

IPC分类号： G02B704

CPC分类号： G01J3/28 ,  G01Q60/22

摘要： The near-field spectrometer 10 comprises a Z-axis scanner 18, 20 for bringing a sample 24 and the tip of a probe 12 close to each other at a predetermined distance within a near-field 26 region when obtaining near-field spectral information and separating them from each other at a predetermined distance outside a near-field 26 region when obtaining back ground spectral information, and a data processor 22 for obtaining the true near-field spectral information free from the background by subtracting the background spectral information from the near-field spectral information, characterized in that a background information collector, during the separation of the sample 24 and the tip of the probe 12 at a predetermined distance outside the near-field 26 region, obtains the background spectral information for the corresponding portion to be measured.

摘要翻译： 近场光谱仪10包括Z轴扫描器18,20，用于当获得近场光谱信息时，使样本24和探针12的尖端以近场26区域内的预定距离彼此靠近， 当获得背景光谱信息时，在近场26区域外的预定距离处彼此分离它们;以及数据处理器22，用于通过从近处获得背景光谱信息来从背景中获得没有背景的真实近场光谱信息 场地光谱信息，其特征在于，背景信息采集器在样品24和探针12的尖端在远场26区域外的预定距离分离期间获得用于相应部分的背景光谱信息 测量。

公开(公告)号：US20120184587A1

公开(公告)日：2012-07-19

申请号：US13499190

申请日：2010-09-29

申请人： Seiichi Kobashi ,  Junichiro Uda ,  Sachiho Miyata ,  Tsutomu Inoue ,  Naoki Ashizawa ,  Koji Matsumoto ,  Tetsuya Taniguchi ,  Takashi Iwanaga ,  Osamu Nagata

发明人： Seiichi Kobashi ,  Junichiro Uda ,  Sachiho Miyata ,  Tsutomu Inoue ,  Naoki Ashizawa ,  Koji Matsumoto ,  Tetsuya Taniguchi ,  Takashi Iwanaga ,  Osamu Nagata

IPC分类号： A61K31/428 ,  C07D417/10 ,  A61P7/00 ,  A61P3/04 ,  A61P19/06 ,  A61P3/10 ,  A61P9/12 ,  A61P9/10 ,  A61P7/02 ,  C07D277/62 ,  A61P3/06

CPC分类号： C07D277/62 ,  C07D417/02 ,  C07D417/10

摘要： Disclosed are a novel compound and a pharmaceutical product, each having a remarkable uricosuric effect. Specifically disclosed are: a novel phenol derivative represented by general formula (1) that is shown in FIG. 1; a pharmaceutically acceptable salt thereof; a hydrate of the derivative or the salt; and a solvate of the derivative or the salt. (In the formula, R1 and R2 may be the same or different and each represents a lower alkyl group, a lower alkenyl group, a lower alkynyl group, a lower alkoxy group, a haloalkyl group, a haloalkoxy group, an alkylsulfanyl group, an alkylsulfinyl group, an alkylsulfonyl group, a lower alkyl-substituted carbamoyl group, a saturated nitrogen-containing heterocyclic N-carbonyl group, a halogen atom, a cyano group or a hydrogen atom; R3 represents a lower alkyl group, a haloalkyl group, a halogen atom, a hydroxy group or a hydrogen atom; and X represents a sulfur atom, an —S(═O)— group or an —S(═O)2— group.)

摘要翻译： 公开了一种新型化合物和药物，其具有显着的尿酸营养作用。 具体公开的是：图1所示的通式（1）表示的新型苯酚衍生物。 1; 其药学上可接受的盐; 衍生物或盐的水合物; 和衍生物或盐的溶剂化物。 （式中，R 1，R 2可以相同或不同，表示低级烷基，低级烯基，低级炔基，低级烷氧基，卤代烷基，卤代烷氧基，烷基硫烷基， 烷基亚磺酰基，烷基磺酰基，低级烷基取代氨基甲酰基，饱和含氮杂环N-羰基，卤素原子，氰基或氢原子; R3表示低级烷基，卤代烷基， 卤素原子，羟基或氢原子; X表示硫原子，-S（= O） - 基或-S（= O）2 - 基）。

公开(公告)号：US08207379B2

公开(公告)日：2012-06-26

申请号：US12936496

申请日：2009-04-03

申请人： Masaya Akashi ,  Tsutomu Inoue

发明人： Masaya Akashi ,  Tsutomu Inoue

IPC分类号： C07C209/00 ,  C07F15/00

CPC分类号： C07F9/5022 ,  B01J31/1815 ,  B01J31/2409 ,  B01J2231/643 ,  B01J2531/0205 ,  B01J2531/0244 ,  B01J2531/821 ,  C07B53/00 ,  C07B2200/07 ,  C07C213/00 ,  C07C231/18 ,  C07F9/65517 ,  C07F15/0053 ,  C07F17/02 ,  C07C233/73

摘要： A novel ruthenium compound that is useful as an asymmetric reduction catalyst for carbonyl compounds. The ruthenium compound of the present invention is represented by a formula (I): (Ru(X)2(Pxx)[R1R2C(NH2)—R3R4C(NH2)] (I)), and when this compound is used as an asymmetric reduction catalyst, an optically active aminoalcohol compound can be produced from an α-aminoketone, and particularly a compound represented by formula (IV), with high stereoselectivity and high yield.

摘要翻译： 一种可用作羰基化合物不对称还原催化剂的新型钌化合物。 本发明的钌化合物由式（I）表示：（Ru（X）2（Pxx）[R1R2C（NH2）-R3R4C（NH2）]（I）），当该化合物用作不对称 可以由α-氨基酮，特别是式（IV）表示的化合物以高立体选择性和高产率制备光学活性氨基醇化合物。