摘要:
Disclosed are a novel compound and a pharmaceutical product, each having a remarkable uricosuric effect. Specifically disclosed are: a novel phenol derivative represented by general formula (1) that is shown in FIG. 1; a pharmaceutically acceptable salt thereof; a hydrate of the derivative or the salt; and a solvate of the derivative or the salt. (In the formula, R1 and R2 may be the same or different and each represents a lower alkyl group, a lower alkenyl group, a lower alkynyl group, a lower alkoxy group, a haloalkyl group, a haloalkoxy group, an alkylsulfanyl group, an alkylsulfinyl group, an alkylsulfonyl group, a lower alkyl-substituted carbamoyl group, a saturated nitrogen-containing heterocyclic N-carbonyl group, a halogen atom, a cyano group or a hydrogen atom; R3 represents a lower alkyl group, a haloalkyl group, a halogen atom, a hydroxy group or a hydrogen atom; and X represents a sulfur atom, an —S(═O)— group or an —S(═O)2— group.)
摘要:
Disclosed are a novel compound and a pharmaceutical product, each having a remarkable uricosuric effect. Specifically disclosed are: a novel phenol derivative represented by general formula (1) that is shown in FIG. 1; a pharmaceutically acceptable salt thereof; a hydrate of the derivative or the salt; and a solvate of the derivative or the salt. (In the formula, R1 and R2 may be the same or different and each represents a lower alkyl group, a lower alkenyl group, a lower alkynyl group, a lower alkoxy group, a haloalkyl group, a haloalkoxy group, an alkylsulfanyl group, an alkylsulfinyl group, an alkylsulfonyl group, a lower alkyl-substituted carbamoyl group, a saturated nitrogen-containing heterocyclic N-carbonyl group, a halogen atom, a cyano group or a hydrogen atom; R3 represents a lower alkyl group, a haloalkyl group, a halogen atom, a hydroxy group or a hydrogen atom; and X represents a sulfur atom, an —S(═O)— group or an —S(═O)2— group.)
摘要:
A novel 1,2,4-triazole compound which is useful as a therapeutic agent for hyperuricemia and gout due to hyperuricemia is provided. A compound is represented by the following general formula (1): wherein R2 represents an unsubstituted or substituted pyridyl group, R1 represents a similar pyridyl group, a pyridine-N-oxide group corresponding to these pyridyl groups, or a phenyl group, and R3 represents hydrogen or a lower alkyl group substituted with pivaloyloxy group and R3 bonds to a nitrogen atom in the ring. A process for production of a compound by reacting a nitrile and a hydrazide, and a therapeutic agent, particularly a xanthine oxidase inhibitor are also provided.
摘要:
A novel 1,2,4-triazole compound which is useful as a therapeutic agent for hyperuricemia and gout due to hyperuricemia is provided. A compound is represented by the following general formula (1): wherein R2 represents an unsubstituted or substituted pyridyl group, R1 represents a similar pyridyl group, a pyridine-N-oxide group corresponding to these pyridyl groups, or a phenyl group, and R3 represents hydrogen or a lower alkyl group substituted with pivaloyloxy group and R3 bonds to a nitrogen atom in the ring. A process for production of a compound by reacting a nitrile and a hydrazide, and a therapeutic agent, particularly a xanthine oxidase inhibitor are also provided.
摘要:
An example of an optical disc apparatus includes a top case and a bottom case. The top case includes a tab extending downward from one end of the top case. The tab includes a protrusion protruding inward. The bottom case includes a lower-side folded portion formed by folding inward an upper end of one side surface of the bottom case. The lower-side folded portion includes a cantilever spring. The cantilever spring includes a spring portion extending in a vertical direction and a curved portion formed by folding inward an upper part of the spring portion. The protrusion comes into contact with the curved portion when the top case is being affixed to the bottom case and is in contact with the spring portion under a state where the top case is affixed to the bottom case.
摘要:
Provided are compounds having an excellent hypoglycemic action and a β cell- or pancreas-protecting action or a pharmaceutically acceptable salt thereof, and a pharmaceutical composition having an excellent therapeutic effect and/or prophylactic effect on type 1 diabetes, type 2 diabetes, and the like, which cause an increase in the blood sugar level due to abnormal sugar metabolism. A compound represented by general formula (I), or a pharmaceutically acceptable salt thereof, is disclosed.
摘要:
A server (3) includes a server communication unit (302) for communicating with a portable terminal (1) and a home appliance (2), a position-determining unit (304) for acquiring information on a position of the terminal (1) during communication, an initial screen storage (305) for storing different position conditions and a collection of screen information defining respective content of initial screens corresponding to the conditions, and an activation unit (306). If position information obtained based on the information on the position acquired through the position-determining unit (304) corresponds to any position condition of the different position conditions, the unit (306) retrieves screen information defining content of an initial screen corresponding to the position condition from the storage (305) to provide the terminal (1) with the information.
摘要:
A magnetic recording medium includes a recording layer having a granular structure in which magnetic particles are dispersed within a non-magnetic base, and a non-magnetic material embedded in grooves of patterns formed on the recording layer. The magnetic particles have an inverted truncated cone shape with a diameter larger in an upper region of the recording layer than in a lower region of the recording layer.
摘要:
An optical disc drive including a conductive plate provided on a front surface of a disc tray. The conductive plate includes a structure of a hook portion at two places on the right and left and a structure of a pressure bar spring on the side end, in which the conductive plate is fixed using hook holes provided on the disc tray and the pressure bar spring presses and grounds a cabinet with the disc tray loaded in the inside of the cabinet.
摘要:
Provided is a wavelength selective switch which includes: at least one input port; a dispersive portion for dispersing wavelength-multiplexed light input from the input port into wavelength-demultiplexed lights; a condenser element for condensing the wavelength-demultiplexed lights dispersed by the dispersive portion; a deflection portion having deflection elements for deflecting, for each wavelength-demultiplexed light condensed by the condenser element; at least one output port for outputting the wavelength-demultiplexed lights deflected by the deflection portion. A light-condensing position shift compensating element is disposed in an optical path between the input port and the dispersive portion or in the dispersive portion, for compensating light-condensing position shift of the wavelength-demultiplexed lights relative to the deflection element, light-condensing position shift being generated based on the arrangement of the input ports.