公开(公告)号：US20060078010A1

公开(公告)日：2006-04-13

申请号：US11017654

申请日：2004-12-22

申请人： Young Kim ,  Eun Nam ,  Kyoung Cho ,  Bo Kim ,  Myung Oh

发明人： Young Kim ,  Eun Nam ,  Kyoung Cho ,  Bo Kim ,  Myung Oh

IPC分类号： H01S3/098

CPC分类号： H01S3/067 ,  H01S3/0675 ,  H01S3/07 ,  H01S3/0809 ,  H01S3/082 ,  H01S3/1055

摘要： Provided is a millimeter-wave band frequency optical oscillator that can be used as an oscillation frequency signal source for a millimeter-wave forwarded to wireless subscribers from a base station of a millimeter-wave wireless subscriber communication system for a next generation (e.g., fifth generation) ultra-high speed wireless internet service. A pair of an optical fiber amplifier and an optical fiber grating mirror is connected to each of input/output ports of a loop mirror in parallel, so that a dual mode laser resonator is formed which can make simultaneous oscillation in two laser modes suitable for each wavelength. Accordingly, it is possible to obtain a light source that is modulated to a ultra-high frequency (over 60 GHz) by a beat phenomenon between the two laser modes.

摘要翻译： 提供了一种毫米波段频率光学振荡器，其可以用作从用于下一代的毫米波无线用户通信系统的基站转发到无线用户的毫米波的振荡频率信号源（例如，第五 一代）超高速无线互联网服务。 一对光纤放大器和光纤光栅反射镜并联连接到环形反射镜的每个输入/输出端口，从而形成双模式激光谐振器，其可以在适合于每个激光模式的两种激光模式中同时振荡 波长。 因此，可以通过两种激光模式之间的拍子现象来获得被调制到超高频（超过60GHz）的光源。

公开(公告)号：US20070123697A1

公开(公告)日：2007-05-31

申请号：US10581597

申请日：2004-12-04

申请人： Ji Sook Park ,  Jong Chung ,  Min Baek ,  Jee Ahn ,  Ki Kim ,  Hyung Park ,  Dong Lee ,  Myung Oh

发明人： Ji Sook Park ,  Jong Chung ,  Min Baek ,  Jee Ahn ,  Ki Kim ,  Hyung Park ,  Dong Lee ,  Myung Oh

IPC分类号： C07K14/56

CPC分类号： C07K14/565 ,  C12P21/02

摘要： Provided is a process for purifying human interferon beta from a recombinant human interferon beta-containing culture comprising performing affinity chromatography and cation exchange chromatography, wherein the affinity chromatography includes: adsorbing the interferon beta-containing culture to an equilibrated affinity chromatography column, followed by washing with an equilibration buffer solution; washing the column with a washing buffer solution A of pH 6.5-7.5 containing 30-60 wt % of propylene glycol and a washing buffer solution B of pH 6.5-7.5 containing 10-30 wt % of propylene glycol and 1-2M NaCl; and eluting a human interferon beta-containing fraction with a buffer solution of pH 6.5-7.5 containing 40-60 wt % of propylene glycol and 1-2M NaCl.

摘要翻译： 提供了一种从重组人类干扰素β的培养物中纯化人类干扰素β的方法，包括进行亲和层析和阳离子交换层析，其中亲和层析包括：将含干扰素β的培养物吸附到平衡的亲和色谱柱上，然后洗涤 用平衡缓冲溶液; 用含有30-60重量％丙二醇的pH 6.5-7.5的洗涤缓冲溶液A和pH6.5-7.5的洗涤缓冲液B洗涤柱子，其中含有10-30重量％的丙二醇和1-2M的NaCl; 并用含有40-60重量％丙二醇和1-2M NaCl的pH 6.5-7.5的缓冲溶液洗脱人类含有干扰素β的级分。

公开(公告)号：US20070093649A1

公开(公告)日：2007-04-26

申请号：US10581602

申请日：2004-12-04

申请人： Ji Sook Park ,  Min Baek ,  Jee Ahn ,  Ki Kim ,  Hyung Park ,  Dong Lee ,  Myung Oh

发明人： Ji Sook Park ,  Min Baek ,  Jee Ahn ,  Ki Kim ,  Hyung Park ,  Dong Lee ,  Myung Oh

IPC分类号： C07K14/56

CPC分类号： C07K14/565 ,  C07K5/06139

摘要： Provided is a process for purifying human interferon beta from a recombinant human interferon beta-containing culture comprising performing affinity chromatography and reversed-phase high-performance liquid chromatography (RP-HPLC), wherein the affinity chromatography includes: adsorbing the interferon beta-containing culture to an equilibrated affinity chromatography column, followed by washing with an equilibration buffer solution; washing the column with a washing buffer solution A of pH 6.5-7.5 containing 30-60 wt % of propylene glycol and a washing buffer solution B of pH 6.5-7.5 containing 10-30 wt % of propylene glycol and 1-2M NaCl; and eluting a human interferon beta-containing fraction with a buffer solution of pH 6.5-7.5 containing 40-60 wt % of propylene glycol and 1-2M NaCl.

摘要翻译： 提供了一种从重组人类干扰素β培养物中纯化人类干扰素β的方法，包括进行亲和层析和反相高效液相色谱（RP-HPLC），其中亲和层析包括：吸附含有干扰素β的培养物 平衡的亲和层析柱，然后用平衡缓冲液洗涤; 用含有30-60重量％丙二醇的pH 6.5-7.5的洗涤缓冲溶液A和pH6.5-7.5的洗涤缓冲液B洗涤柱子，其中含有10-30重量％的丙二醇和1-2M的NaCl; 并用含有40-60重量％丙二醇和1-2M NaCl的pH 6.5-7.5的缓冲溶液洗脱人类含有干扰素β的级分。