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![Derivatives of imidazo[1,2-a]pyridine-2-carboxamides, preparation method thereof and use of same in therapeutics](/abs-image/US/2010/04/27/US07704989B2/abs.jpg.150x150.jpg)
1.发明授权Derivatives of imidazo[1,2-a]pyridine-2-carboxamides, preparation method thereof and use of same in therapeutics 有权咪唑并[1,2-a]吡啶-2-甲酰胺的衍生物，其制备方法及其在治疗中的应用公开(公告)号：US07704989B2
公开(公告)日：2010-04-27
申请号：US12337007
申请日：2008-12-17
IPC分类号： A61K31/437 , C07D471/04 , A61P25/28
CPC分类号： C07D471/04
摘要： The present invention is related to a compound of formula (I): wherein R1, R2, R3, R4 and X are as defined herein, or an addition salt with an acid thereof, its pharmaceutical composition or use for treating or preventing diseases involving Nurr-1 nuclear receptors, also known as NR4A2, NOT, TINUR, RNR-1 and HZF3.
摘要翻译： 本发明涉及式（I）化合物：其中R1，R2，R3，R4和X如本文所定义，或其与酸的加成盐，其药物组合物或用于治疗或预防涉及Nurr的疾病的用途 -1核受体，也称为NR4A2，NOT，TINUR，RNR-1和HZF3。
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![Derivatives of imidazo[1,2-a]pyridine-2-carboxamides, preparation method thereof and use of same in therapeutics](/abs-image/US/2013/03/26/US08404848B2/abs.jpg.150x150.jpg)
2.发明授权Derivatives of imidazo[1,2-a]pyridine-2-carboxamides, preparation method thereof and use of same in therapeutics 有权咪唑并[1,2-a]吡啶-2-甲酰胺的衍生物，其制备方法及其在治疗中的应用公开(公告)号：US08404848B2
公开(公告)日：2013-03-26
申请号：US12711779
申请日：2010-02-24
IPC分类号： C07D471/04 , A61K31/437 , A61P25/28
CPC分类号： C07D471/04
摘要： The present invention is related to a compound of formula (I): wherein R1, R2, R3, R4 and X are as defined herein, or an addition salt with an acid thereof, its pharmaceutical composition or use for treating or preventing diseases involving Nurr-1 nuclear receptors, also known as NR4A2, NOT, TINUR, RNR-1 and HZF3.
摘要翻译： 本发明涉及式（I）化合物：其中R1，R2，R3，R4和X如本文所定义，或其与酸的加成盐，其药物组合物或用于治疗或预防涉及Nurr的疾病的用途 -1核受体，也称为NR4A2，NOT，TINUR，RNR-1和HZF3。
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![2-ARYL-6-PHENYLIMIDAZO[1,2-a]PYRIDINE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF](/abs-image/US/2009/10/08/US20090253735A1/abs.jpg.150x150.jpg)
3.发明申请2-ARYL-6-PHENYLIMIDAZO[1,2-a]PYRIDINE DERIVATIVES, PREPARATION THEREOF AND THERAPEUTIC USE THEREOF 有权2-亚芳基-6-苯基咪唑并[1,2-a]吡啶衍生物，其制备方法及其治疗用途公开(公告)号：US20090253735A1
公开(公告)日：2009-10-08
申请号：US12407449
申请日：2009-03-19
IPC分类号： A61K31/437 , C07D471/04 , A61P25/00 , A61P25/16 , A61P25/28
CPC分类号： C07D471/04
摘要： The present invention is related to a compound of formula (I) wherein R1, R2, R3 and R4 are as defined herein, or an addition salt of an cid thereof, the pharmaceutical composition and preparation thereof, and the therapeutic use thereof in the treatment or the prevention of diseases involving Nurr-1 nuclear receptors, also known as NR4A2, NOT, TINUR, RNR-1 and HZF3.
摘要翻译： 本发明涉及其中R 1，R 2，R 3和R 4如本文所定义的式（I）化合物或其酸的加成盐，其药物组合物及其制备及其在治疗中的治疗用途 或预防涉及Nurr-1核受体，也称为NR4A2，NOT，TINUR，RNR-1和HZF3的疾病。
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![2-aryl-6-phenylimidazo[1,2-a]pyridine derivatives, preparation thereof and therapeutic use thereof](/abs-image/US/2011/03/29/US07915284B2/abs.jpg.150x150.jpg)
4.发明授权2-aryl-6-phenylimidazo[1,2-a]pyridine derivatives, preparation thereof and therapeutic use thereof 有权2-芳基-6-苯基咪唑并[1,2-a]吡啶衍生物，其制备及其治疗用途公开(公告)号：US07915284B2
公开(公告)日：2011-03-29
申请号：US12407449
申请日：2009-03-19
IPC分类号： A61K31/437 , C07D471/04 , A61P25/00 , A61P25/16 , A61P25/28
CPC分类号： C07D471/04
摘要： The present invention is related to a compound of formula (I) wherein R1, R2, R3 and R4 are as defined herein, or an addition salt of an acid thereof, the pharmaceutical composition and preparation thereof, and the therapeutic use thereof in the treatment or the prevention of diseases involving Nurr-1 nuclear receptors, also known as NR4A2, NOT, TINUR, RNR-1 and HZF3.
摘要翻译： 本发明涉及其中R 1，R 2，R 3和R 4如本文所定义的式（I）化合物或其酸的加成盐，其药物组合物及其制备及其在治疗中的治疗用途 或预防涉及Nurr-1核受体，也称为NR4A2，NOT，TINUR，RNR-1和HZF3的疾病。
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