公开(公告)号：US07943663B2

公开(公告)日：2011-05-17

申请号：US11992196

申请日：2006-09-29

申请人： Yukihiro Aoshima ,  Masaaki Nakai ,  Kenji Katano ,  Asako Okada

发明人： Yukihiro Aoshima ,  Masaaki Nakai ,  Kenji Katano ,  Asako Okada

IPC分类号： A61K31/36

CPC分类号： B01D11/0407 ,  B01D9/0013 ,  B01D9/0022 ,  C07B53/00 ,  C07B61/00 ,  C07B63/00 ,  C07D493/04

摘要： To provide a process and an apparatus by means of which a composition that contains episesamin in a concentration greater than 50 wt % on the basis of the sum weight of sesamin and episesamin can be produced conveniently and at high yield.There are provided a process and an apparatus which comprise the step of applying epimerization to sesamin or a sesamin-containing composition so that at least part of the sesamin is converted to episesamin and the step of selectively crystallizing episesamin by recrystallization and by means of which a composition that contains episesamin in a concentration greater than 50 wt % can be produced conveniently and at high yield.

摘要翻译： 为了提供方法和装置，通过该方法和装置，可以方便地且高产率地制备基于芝麻素和表芝麻素的总重量含有浓度大于50重量％的表芝麻素的组合物。 提供了一种方法和装置，其包括将差向异构化施加于芝麻素或含芝麻素的组合物，使得至少部分芝麻素转化为异芝麻素，以及通过重结晶选择性结晶异芝素的步骤， 含有浓度大于50wt％的表芝麻素的组合物可以方便地且高产率地制备。

公开(公告)号：US20090163583A1

公开(公告)日：2009-06-25

申请号：US11992196

申请日：2006-09-29

申请人： Yukihiro Aoshima ,  Masaaki Nakai ,  Kenji Katano ,  Asako Okada

发明人： Yukihiro Aoshima ,  Masaaki Nakai ,  Kenji Katano ,  Asako Okada

IPC分类号： A61K31/341 ,  B01J19/00

CPC分类号： B01D11/0407 ,  B01D9/0013 ,  B01D9/0022 ,  C07B53/00 ,  C07B61/00 ,  C07B63/00 ,  C07D493/04

摘要： To provide a process and an apparatus by means of which a composition that contains episesamin in a concentration greater than 50 wt % on the basis of the sum weight of sesamin and episesamin can be produced conveniently and at high yield.There are provided a process and an apparatus which comprise the step of applying epimerization to sesamin or a sesamin-containing composition so that at least part of the sesamin is converted to episesamin and the step of selectively crystallizing episesamin by recrystallization and by means of which a composition that contains episesamin in a concentration greater than 50 wt % can be produced conveniently and at high yield.

摘要翻译： 为了提供方法和装置，通过该方法和装置，可以方便地且高产率地制备基于芝麻素和表芝麻素的总重量含有浓度大于50重量％的表芝麻素的组合物。 提供了一种方法和装置，其包括将差向异构化施加于芝麻素或含芝麻素的组合物，使得至少部分芝麻素转化为异芝麻素，以及通过重结晶选择性结晶异芝素的步骤， 含有浓度大于50wt％的表芝麻素的组合物可以方便地且高产率地制备。

公开(公告)号：US20110104360A1

公开(公告)日：2011-05-05

申请号：US12745292

申请日：2008-12-17

申请人： Eiichiro Ono ,  Asako Okada ,  Yuko Fukui

发明人： Eiichiro Ono ,  Asako Okada ,  Yuko Fukui

IPC分类号： C12N15/63 ,  C12N9/02 ,  C07H21/04 ,  C12N5/10 ,  A01H5/00 ,  C12P21/02 ,  C12P1/00 ,  C12N15/82 ,  C07D493/04 ,  C12P17/18 ,  A23L1/305

CPC分类号： C12P17/181 ,  A23L33/18 ,  C07D493/04 ,  C12N9/0004 ,  C12N9/0071 ,  C12N15/8255

摘要： The invention provides an enzyme having a lignan-hydroxylating activity, particularly an enzyme capable of catalyzing the reaction of transferring a hydroxyl group to a lignan, an enzyme capable of catalyzing the hydroxylation of piperitol to 9-hydroxylpiperitol or pinoresinol to 9-hydroxylpinoresinol. The invention provides a polypeptide having a lignan-hydroxylating activity; a polynucleotide encoding the same; a vector or transformant comprising the polynucleotide; a method for producing a polypeptide having a lignan-hydroxylating activity which comprises using the transformant; and so on. The transformant wherein the polynucleotide is expressibly introduced is useful for the hydroxylation of a lignan or for the production of a product using the same in the food sector and a variety of industry sectors.

摘要翻译： 本发明提供了具有木酚素羟化活性的酶，特别是能够催化将羟基转移到木脂素的反应的酶，能够催化胡椒醇羟基化为9-羟基哌啶醇或者尖晶石酚至9-羟基苯甲醇的酶。 本发明提供了具有木酚素羟化活性的多肽; 编码该多核苷酸的多核苷酸; 包含所述多核苷酸的载体或转化体; 一种生产具有木酚素羟化活性的多肽的方法，其包括使用所述转化体; 等等。 其中可表达引入的多核苷酸的转化体可用于木质素的羟基化或用于在食品部门和各种工业部门中使用其的产品的生产。

公开(公告)号：US08288613B2

公开(公告)日：2012-10-16

申请号：US12745292

申请日：2008-12-17

申请人： Eiichiro Ono ,  Asako Okada ,  Yuko Fukui

发明人： Eiichiro Ono ,  Asako Okada ,  Yuko Fukui

IPC分类号： C12N15/82 ,  C12N15/52 ,  C12N15/63 ,  C12N9/00 ,  C12N15/29 ,  C12P19/04 ,  C12P21/02

CPC分类号： C12P17/181 ,  A23L33/18 ,  C07D493/04 ,  C12N9/0004 ,  C12N9/0071 ,  C12N15/8255

摘要： The invention provides an enzyme having a lignan-hydroxylating activity, particularly an enzyme capable of catalyzing the reaction of transferring a hydroxyl group to a lignan, an enzyme capable of catalyzing the hydroxylation of piperitol to 9-hydroxylpiperitol or pinoresinol to 9-hydroxylpinoresinol. The invention provides a polypeptide having a lignan-hydroxylating activity; a polynucleotide encoding the same; a vector or transformant comprising the polynucleotide; a method for producing a polypeptide having a lignan-hydroxylating activity which comprises using the transformant; and so on. The transformant wherein the polynucleotide is expressibly introduced is useful for the hydroxylation of a lignan or for the production of a product using the same in the food sector and a variety of industry sectors.

摘要翻译： 本发明提供了具有木酚素羟化活性的酶，特别是能够催化将羟基转移到木脂素的反应的酶，能够催化胡椒醇羟基化为9-羟基哌啶醇或者尖晶石酚到9-羟基苯甲醇的酶。 本发明提供了具有木酚素羟化活性的多肽; 编码该多核苷酸的多核苷酸; 包含所述多核苷酸的载体或转化体; 一种生产具有木酚素羟化活性的多肽的方法，其包括使用所述转化体; 等等。 其中可表达引入的多核苷酸的转化体可用于木质素的羟基化或用于在食品部门和各种工业部门中使用其的产品的生产。