摘要:
In a prefilled syringe including an elastic seal member to be pierced with a needle for use to eject a protein pharmaceutical preparation therefrom, the elastic seal member ensures smooth and reliable piercing thereof with the needle while reliably preventing an active substance of the protein pharmaceutical preparation from being adsorbed thereon. When a protective film (3) is laminated to a top surface of a seal body (2) of an elastic material, the protective film (3) is stretched to a greater extent by a recess (4) provided in the top surface. Further, the piercing portion to be pierced with the needle is provided in a bottom of the recess (4). Thus, the protective film (3) is formed as locally having a smaller thickness in the piercing portion.
摘要:
In a prefilled syringe including an elastic seal member to be pierced with a needle for use to eject a protein pharmaceutical preparation therefrom, the elastic seal member ensures smooth and reliable piercing thereof with the needle while reliably preventing an active substance of the protein pharmaceutical preparation from being adsorbed thereon. When a protective film (3) is laminated to a top surface of a seal body (2) of an elastic material, the protective film (3) is stretched to a greater extent by a recess (4) provided in the top surface. Further, the piercing portion to be pierced with the needle is provided in a bottom of the recess (4). Thus, the protective film (3) is formed as locally having a smaller thickness in the piercing portion.
摘要:
A method and an apparatus for producing a container packing filler are provided, which ensure that a net can be correctly and speedily rolled up into a bulk or ball shape. A stretchable tubular net (N) is fitted around a columnar support member (6). Then, a distal portion of the net is forcibly folded radially outward or inward by a plurality of roller belts (30) disposed circumferentially of the net (N), while the roller belts (30) are moved toward a net proximal side axially of the net (N), whereby the net (N) is rolled up radially outward or inward with the distal portion thereof being forcibly folded by circular rotation and axial movement of the roller belts (30) to form an annular roll portion (C).
摘要:
The present invention provides an infusion vessel, which is capable of separately containing a drug and a infusion liquid in a sterile manner and mixing the drug with the infusion liquid in a sterile manner by a simple operation for use, while ensuring the sterility of a connector thereof. The infusion vessel according to the present invention comprises a bag (2) for containing a infusion liquid, a two-mouth vial (3) for containing a drug, and a joint (4) connecting the bag and the vial. A lower mouth portion (33) of the vial (3) is sealed with a rubber plug (7). The joint (4) is air-tightly connected to a liquid outlet port (21) provided in a bottom portion of the bag (2), and extends downward. The joint (4) has an opening (46) for communication between the inside and the outside thereof. An O-ring (6) and an intermediate rubber plug (5) are respectively attached to the joint (4) above and below the opening (46), and fitted in the upper mouth portion (32) of the vial (3) in an axially movable manner.
摘要:
A filter-equipped container which, particularly in a small-sized eyedrop bottle or the like, is capable of accurate dropping while preventing bubbles from being involved when a contents liquid is to be delivered through a delivery port. To solve such problem, a plug body 12 disposed in the mouth of a bottle 10 is provided with a delivery passage for delivering contents liquid received in the bottle 10, the delivery passage being provided with a filter 25. The filter 25 is composed of a filter film 25a for filtering bacteria to prevent the latter from permeating from upstream to downstream as seen in the direction of delivery, and a contents liquid holding member 25b of porous material that has microscopic pores, disposed upstream of the filter film 25a, the contents liquid holding member 25b being in planar contact with the filter film 25a.
摘要:
A discharging container with a filter capable of sucking content liquid remaining on the downstream side of the filter to the upstream side of the filter, capable of accurately dripping the content liquid while avoiding an air lock state, and manufacturable at reduce cost, particularly in an instillation vial, comprising a bottle formed by laminating an inner layer separable from an outer layer on the inner surface of the outer layer and a plug body fitted to the mouth part of the bottle. A discharging passage for discharging the content liquid stored in the body part of the inner layer is formed in the plug body, and the filter is installed in the discharging passage. The inner layer has a restoring property to expand so that a pressure difference between an internal negative pressure and the atmospheric pressure is increased larger than filtration resistance of the filter, a negative pressure is produced in the inner layer by the recovering property of the inner layer, and the liquid remaining on the secondary side of the filter is sucked to the primary side of the filter.
摘要:
A surgical operation training device 13 comprises a simulation body 83 subjected to a predetermined treatment during surgical operation training, a holder 84 for holding the simulation body 83 from below, a support 85 for supporting the holder 84 workably, a wire 86 for coupling the holder 84 with the support 85, and a control unit 71 for controlling operation of the holder 84. The wire 86 is formed of a shape memory material which can contract from an original shape when a current flows through the wire. The control unit 71 comprises a drive signal generating means 114 for supplying a current to the wire 86 at a predetermined timing and for performing operation control on the holder 84 with a change in the shape of the wire 86 by varying the supply state of current to the wire 86.
摘要:
A container packing filler (1) includes an annular roll portion (3) formed by folding one of axially opposite end portions of a stretchable tubular net (2) radially outward and rolling the net (2) toward the other end portion of the net (2), and a rigid holder portion (4) provided at the other end portion of the net (2). The holder portion (4) has a necessary and sufficient axial length and a maximum width (W) greater than the diameter (R) of a center hole (5) of the annular roll portion (3) so that, when the holder portion (4) of the packing filler (1) is squeezed into the center hole (5) of the annular roll portion (3), the annular roll portion (3) is expanded from the inside thereof by the holder portion (4) and layers of the annular roll portion (3) are unitarily rolled inward. Therefore, the bulging of only the outermost layer of the annular roll portion is prevented which may otherwise occur when the holder portion is squeezed. Thus, the packing filler provides a sufficient cushioning effect, and prevents inadvertent scattering of tablets or the like.
摘要:
This invention provides a filter-equipped container which, particularly in a small-sized eyedrop bottle or the like, is capable of accurate dropping while preventing bubbles from being involved when a contents liquid is to be delivered through a delivery port. To solve such problem, a plug body 12 disposed in the mouth of a bottle 10 is provided with a delivery passage for delivering contents liquid received in the bottle 10, the delivery passage being provided with a filter 25. The filter 25 is composed of a filter film 25a for filtering bacteria to prevent the latter from permeating from upstream to downstream as seen in the direction of delivery, and a contents liquid holding member 25b of porous material disposed upstream of the filter film 25a, the contents liquid holding member 25b being in planar contact with the filter film 25a.
摘要:
The present invention provides a discharging container whose main part is a squeeze-bottle adapted for use as eyedroppers and transparent to such a degree as required. This container has to perfectly shut off ambient air and bacteria not to flowing into a liquid content of the container so as to keep it sterilized even after unsealed for use. The discharging container has a laminated bottle 2, and a stopper 3 attached to a finish 2a of the laminated bottle, the bottle being composed of an outer layer 21 and an inner layer 22 delaminating from the outer layer 21. A vent hole 4 is formed in the outer layer so as to introduce ambient air in between the outer and inner layers 21, 22. A discharging passage 10 is formed in the stopper 3 so as to exude through it a liquid content inside the inner layer 22, and the stopper further has a check valve 8 and a filter 7 disposed on the downstream side of the valve.