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公开(公告)号：US07855271B2
公开(公告)日：2010-12-21
申请号：US11930080
申请日：2007-10-30
IPC分类号： C07K14/00
CPC分类号： C07K16/3015 , A61K35/12 , A61K38/00 , A61K39/00 , A61K2039/5154 , A61K2039/57 , C07K14/47 , C07K14/4748 , C07K2317/34 , C07K2319/00 , C12N9/00 , C12Q1/6886 , C12Q2600/156 , C12Q2600/158 , G01N33/57415 , G01N2500/00
摘要： Compositions and methods for the therapy and diagnosis of cancer, particularly breast cancer, are disclosed. Illustrative compositions comprise one or more breast tumor polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases, particularly breast cancer.
摘要翻译： 公开了用于治疗和诊断癌症，特别是乳腺癌的组合物和方法。 示例性组合物包含一种或多种乳腺肿瘤多肽，其免疫原性部分，编码该多肽的多核苷酸，表达此类多肽的抗原呈递细胞，以及对表达该多肽的细胞特异的T细胞。 所公开的组合物可用于例如疾病，特别是乳腺癌的诊断，预防和/或治疗。
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公开(公告)号：US07563880B2
公开(公告)日：2009-07-21
申请号：US10714389
申请日：2003-11-13
申请人： Davin C Dillon , Yuqiu Jiang
发明人： Davin C Dillon , Yuqiu Jiang
CPC分类号： C07K14/4748 , A61K38/00 , A61K39/00 , A61K2039/5154 , A61K2039/5156 , A61K2039/5158 , C07K14/47 , C07K2319/00 , G01N33/57415
摘要： Compositions and methods for the therapy and diagnosis of cancer, particularly breast cancer, are disclosed. Illustrative compositions comprise one or more breast tumor polypeptides, immunogenic portions thereof, polynucleotides that encode such polypeptides, antigen presenting cell that expresses such polypeptides, and T cells that are specific for cells expressing such polypeptides. The disclosed compositions are useful, for example, in the diagnosis, prevention and/or treatment of diseases, particularly breast cancer.
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