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公开(公告)号:US20210178011A1
公开(公告)日:2021-06-17
申请号:US17179013
申请日:2021-02-18
申请人: Z-Medica, LLC
发明人: Dina Dubey , Denny Lo
摘要: Hemostatic devices for promoting blood clotting can include a substrate (e.g., gauze, textile, sponge, sponge matrix, one or more fibers, etc.), a hemostatic material disposed thereon such as kaolin clay, and a binder material such as crosslinked calcium alginate with a high guluronate monomer molar percentage disposed on the substrate to substantially retain the hemostatic material material. When the device is used to treat a bleeding wound, at least a portion of the clay material comes into contact with blood to accelerate clotting. Moreover, when exposed to blood, the binder has low solubility and retains a majority of the clay material on the gauze. A bandage that can be applied to a bleeding wound to promote blood clotting includes a flexible substrate and a gauze substrate mounted thereon.
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公开(公告)号:US11559601B2
公开(公告)日:2023-01-24
申请号:US17179013
申请日:2021-02-18
申请人: Z-Medica, LLC
发明人: Dina Dubey , Denny Lo
摘要: Hemostatic devices for promoting blood clotting can include a substrate (e.g., gauze, textile, sponge, sponge matrix, one or more fibers, etc.), a hemostatic material disposed thereon such as kaolin clay, and a binder material such as crosslinked calcium alginate with a high guluronate monomer molar percentage disposed on the substrate to substantially retain the hemostatic material material. When the device is used to treat a bleeding wound, at least a portion of the clay material comes into contact with blood to accelerate clotting. Moreover, when exposed to blood, the binder has low solubility and retains a majority of the clay material on the gauze. A bandage that can be applied to a bleeding wound to promote blood clotting includes a flexible substrate and a gauze substrate mounted thereon.
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公开(公告)号:US20160193380A1
公开(公告)日:2016-07-07
申请号:US15071520
申请日:2016-03-16
申请人: Z-MEDICA , LLC
发明人: Dina Dubey , Denny Lo
CPC分类号: A61L15/28 , A61L15/18 , A61L15/44 , A61L15/46 , A61L2300/102 , A61L2300/104 , A61L2300/402 , A61L2300/404 , A61L2300/406 , A61L2300/41 , A61L2300/418 , A61L2300/432 , A61L2400/04 , A61L2420/02 , A61L2420/04 , A61L2420/08 , C08L5/04
摘要: Hemostatic devices for promoting blood clotting can include a substrate (e.g., gauze, textile, sponge, sponge matrix, one or more fibers, etc.), a hemostatic material disposed thereon such as kaolin clay, and a binder material such as crosslinked calcium alginate with a high guluronate monomer molar percentage disposed on the substrate to substantially retain the hemostatic material material. When the device is used to treat a bleeding wound, at least a portion of the clay material comes into contact with blood to accelerate clotting. Moreover, when exposed to blood, the binder has low solubility and retains a majority of the clay material on the gauze. A bandage that can be applied to a bleeding wound to promote blood clotting includes a flexible substrate and a gauze substrate mounted thereon.
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公开(公告)号:US09072806B2
公开(公告)日:2015-07-07
申请号:US13922115
申请日:2013-06-19
申请人: Z-Medica, LLC
发明人: Denny Lo , Dina Dubey
CPC分类号: A61L15/28 , A61L15/18 , A61L15/44 , A61L15/46 , A61L2300/102 , A61L2300/104 , A61L2300/402 , A61L2300/404 , A61L2300/406 , A61L2300/41 , A61L2300/418 , A61L2300/432 , A61L2400/04 , A61L2420/02 , A61L2420/04 , A61L2420/08 , C08L5/04
摘要: Hemostatic devices for promoting blood clotting can include a substrate (e.g., gauze, textile, sponge, sponge matrix, one or more fibers, etc.), a hemostatic material disposed thereon such as kaolin clay, and a binder material such as crosslinked calcium alginate with a high guluronate monomer molar percentage disposed on the substrate to substantially retain the hemostatic material material. When the device is used to treat a bleeding wound, at least a portion of the clay material comes into contact with blood to accelerate clotting. Moreover, when exposed to blood, the binder has low solubility and retains a majority of the clay material on the gauze. A bandage that can be applied to a bleeding wound to promote blood clotting includes a flexible substrate and a gauze substrate mounted thereon.
摘要翻译: 用于促进血液凝固的止血装置可以包括底物(例如纱布,纺织品,海绵,海绵基质,一种或多种纤维等),设置在其上的止血材料如高岭土,以及粘合剂材料,例如交联的藻酸钙 其具有设置在基底上的高古罗糖醛酸单体摩尔百分数以基本上保持止血材料。 当该装置用于治疗出血的伤口时,至少一部分粘土材料与血液接触以加速凝血。 此外,当暴露于血液时,粘合剂具有低溶解度并将大部分粘土材料保留在纱布上。 可以应用于流血伤口以促进血液凝固的绷带包括安装在其上的柔性基底和纱布基底。
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公开(公告)号:US10960100B2
公开(公告)日:2021-03-30
申请号:US15429935
申请日:2017-02-10
申请人: Z-Medica, LLC
发明人: Dina Dubey , Denny Lo
摘要: Hemostatic devices for promoting blood clotting can include a substrate (e.g., gauze, textile, sponge, sponge matrix, one or more fibers, etc.), a hemostatic material disposed thereon such as kaolin clay, and a binder material such as crosslinked calcium alginate with a high guluronate monomer molar percentage disposed on the substrate to substantially retain the hemostatic material. When the device is used to treat a bleeding wound, at least a portion of the clay material comes into contact with blood to accelerate clotting. Moreover, when exposed to blood, the binder has low solubility and retains a majority of the clay material on the gauze. A bandage that can be applied to a bleeding wound to promote blood clotting includes a flexible substrate and a gauze substrate mounted thereon.
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公开(公告)号:US09603964B2
公开(公告)日:2017-03-28
申请号:US15071520
申请日:2016-03-16
申请人: Z-MEDICA, LLC
发明人: Dina Dubey , Denny Lo
CPC分类号: A61L15/28 , A61L15/18 , A61L15/44 , A61L15/46 , A61L2300/102 , A61L2300/104 , A61L2300/402 , A61L2300/404 , A61L2300/406 , A61L2300/41 , A61L2300/418 , A61L2300/432 , A61L2400/04 , A61L2420/02 , A61L2420/04 , A61L2420/08 , C08L5/04
摘要: Hemostatic devices for promoting blood clotting can include a substrate (e.g., gauze, textile, sponge, sponge matrix, one or more fibers, etc.), a hemostatic material disposed thereon such as kaolin clay, and a binder material such as crosslinked calcium alginate with a high guluronate monomer molar percentage disposed on the substrate to substantially retain the hemostatic material material. When the device is used to treat a bleeding wound, at least a portion of the clay material comes into contact with blood to accelerate clotting. Moreover, when exposed to blood, the binder has low solubility and retains a majority of the clay material on the gauze. A bandage that can be applied to a bleeding wound to promote blood clotting includes a flexible substrate and a gauze substrate mounted thereon.
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公开(公告)号:US20230149592A1
公开(公告)日:2023-05-18
申请号:US18158039
申请日:2023-01-23
申请人: Z-Medica, LLC
发明人: Dina Dubey , Denny Lo
CPC分类号: A61L15/28 , A61L15/44 , A61L15/46 , A61L15/18 , A61L2400/04 , A61L2300/102 , A61L2300/418 , A61L2420/02 , A61L2420/04 , A61L2300/104 , A61L2300/402 , A61L2300/404 , A61L2300/406 , A61L2300/41 , A61L2300/432 , A61L2420/08
摘要: Hemostatic devices for promoting blood clotting can include a substrate (e.g., gauze, textile, sponge, sponge matrix, one or more fibers, etc.), a hemostatic material disposed thereon such as kaolin clay, and a binder material such as crosslinked calcium alginate with a high guluronate monomer molar percentage disposed on the substrate to substantially retain the hemostatic material material. When the device is used to treat a bleeding wound, at least a portion of the clay material comes into contact with blood to accelerate clotting. Moreover, when exposed to blood, the binder has low solubility and retains a majority of the clay material on the gauze. A bandage that can be applied to a bleeding wound to promote blood clotting includes a flexible substrate and a gauze substrate mounted thereon.
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公开(公告)号:US20170151365A1
公开(公告)日:2017-06-01
申请号:US15429935
申请日:2017-02-10
申请人: Z-Medica, LLC
发明人: Dina Dubey , Denny Lo
CPC分类号: A61L15/28 , A61L15/18 , A61L15/44 , A61L15/46 , A61L2300/102 , A61L2300/104 , A61L2300/402 , A61L2300/404 , A61L2300/406 , A61L2300/41 , A61L2300/418 , A61L2300/432 , A61L2400/04 , A61L2420/02 , A61L2420/04 , A61L2420/08 , C08L5/04
摘要: Hemostatic devices for promoting blood clotting can include a substrate (e.g., gauze, textile, sponge, sponge matrix, one or more fibers, etc.), a hemostatic material disposed thereon such as kaolin clay, and a binder material such as crosslinked calcium alginate with a high guluronate monomer molar percentage disposed on the substrate to substantially retain the hemostatic material. When the device is used to treat a bleeding wound, at least a portion of the clay material comes into contact with blood to accelerate clotting. Moreover, when exposed to blood, the binder has low solubility and retains a majority of the clay material on the gauze. A bandage that can be applied to a bleeding wound to promote blood clotting includes a flexible substrate and a gauze substrate mounted thereon.
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公开(公告)号:US09352066B2
公开(公告)日:2016-05-31
申请号:US14720142
申请日:2015-05-22
申请人: Z-Medica, LLC
发明人: Dina Dubey , Denny Lo
CPC分类号: A61L15/28 , A61L15/18 , A61L15/44 , A61L15/46 , A61L2300/102 , A61L2300/104 , A61L2300/402 , A61L2300/404 , A61L2300/406 , A61L2300/41 , A61L2300/418 , A61L2300/432 , A61L2400/04 , A61L2420/02 , A61L2420/04 , A61L2420/08 , C08L5/04
摘要: Hemostatic devices for promoting blood clotting can include a substrate (e.g., gauze, textile, sponge, sponge matrix, one or more fibers, etc.), a hemostatic material disposed thereon such as kaolin clay, and a binder material such as crosslinked calcium alginate with a high guluronate monomer molar percentage disposed on the substrate to substantially retain the hemostatic material. When the device is used to treat a bleeding wound, at least a portion of the clay material comes into contact with blood to accelerate clotting. Moreover, when exposed to blood, the binder has low solubility and retains a majority of the clay material on the gauze. A bandage that can be applied to a bleeding wound to promote blood clotting includes a flexible substrate and a gauze substrate mounted thereon.
摘要翻译: 用于促进血液凝固的止血装置可以包括底物(例如纱布,纺织品,海绵,海绵基质,一种或多种纤维等),设置在其上的止血材料如高岭土,以及粘合剂材料,例如交联的藻酸钙 其具有设置在基底上的高古罗糖醛酸单体摩尔百分数以基本上保持止血材料。 当该装置用于治疗出血的伤口时,至少一部分粘土材料与血液接触以加速凝血。 此外,当暴露于血液时,粘合剂具有低溶解度并将大部分粘土材料保留在纱布上。 可以应用于流血伤口以促进血液凝固的绷带包括安装在其上的柔性基底和纱布基底。
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公开(公告)号:US20150250918A1
公开(公告)日:2015-09-10
申请号:US14720142
申请日:2015-05-22
申请人: Z-Medica, LLC
发明人: Dina Dubey , Denny Lo
CPC分类号: A61L15/28 , A61L15/18 , A61L15/44 , A61L15/46 , A61L2300/102 , A61L2300/104 , A61L2300/402 , A61L2300/404 , A61L2300/406 , A61L2300/41 , A61L2300/418 , A61L2300/432 , A61L2400/04 , A61L2420/02 , A61L2420/04 , A61L2420/08 , C08L5/04
摘要: Hemostatic devices for promoting blood clotting can include a substrate (e.g., gauze, textile, sponge, sponge matrix, one or more fibers, etc.), a hemostatic material disposed thereon such as kaolin clay, and a binder material such as crosslinked calcium alginate with a high guluronate monomer molar percentage disposed on the substrate to substantially retain the hemostatic material. When the device is used to treat a bleeding wound, at least a portion of the clay material comes into contact with blood to accelerate clotting. Moreover, when exposed to blood, the binder has low solubility and retains a majority of the clay material on the gauze. A bandage that can be applied to a bleeding wound to promote blood clotting includes a flexible substrate and a gauze substrate mounted thereon.
摘要翻译: 用于促进血液凝固的止血装置可以包括底物(例如纱布,纺织品,海绵,海绵基质,一种或多种纤维等),设置在其上的止血材料如高岭土,以及粘合剂材料,例如交联的藻酸钙 其具有设置在基底上的高古罗糖醛酸单体摩尔百分数以基本上保持止血材料。 当该装置用于治疗出血的伤口时,至少一部分粘土材料与血液接触以加速凝血。 此外,当暴露于血液时,粘合剂具有低溶解度并将大部分粘土材料保留在纱布上。 可以应用于流血伤口以促进血液凝固的绷带包括安装在其上的柔性基底和纱布基底。
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