公开(公告)号：US20230365503A1

公开(公告)日：2023-11-16

申请号：US18245552

申请日：2021-09-28

申请人： ZHUHAI UNITED LABORATORIES CO., LTD.

发明人： Peng LI ,  Xiaolin LI ,  Zhi LUO ,  Haiying HE ,  Guoping HU ,  Jian LI ,  Shuhui CHEN

IPC分类号： C07D213/73

CPC分类号： C07D213/73 ,  C07B2200/13

摘要： A crystal form of a pyridinylphenyl compound and a preparation method therefor. Use of the crystal form in the preparation of a medicament of treating related diseases is also comprised.

公开(公告)号：US20240217949A1

公开(公告)日：2024-07-04

申请号：US18429297

申请日：2024-01-31

申请人： ZHUHAI UNITED LABORATORIES CO., LTD.

发明人： Peng LI ,  Xiaolin LI ,  Zhi LUO ,  Haiying HE ,  Guoping HU ,  Jian LI ,  Shuhui CHEN

IPC分类号： C07D401/12 ,  A61K31/4412 ,  A61K31/4418 ,  A61K31/444 ,  A61P27/04 ,  C07D213/73 ,  C07D401/04 ,  C07D401/06

CPC分类号： C07D401/12 ,  A61K31/4412 ,  A61K31/4418 ,  A61K31/444 ,  A61P27/04 ,  C07D213/73 ,  C07D401/04 ,  C07D401/06

摘要： Provided is an aldehyde binder, specifically, disclosed is a compound as represented by formula (II) or a pharmaceutically acceptable salt.

公开(公告)号：US20210070754A1

公开(公告)日：2021-03-11

申请号：US16966112

申请日：2019-01-31

申请人： ZHUHAI UNITED LABORATORIES CO., LTD.

发明人： Weiwei MAO ,  Hao WU ,  Xuejian ZHENG ,  Guoping HU ,  Changqing WEI ,  Jian LI ,  Shuhui CHEN

IPC分类号： C07D471/04 ,  C07D513/04 ,  A61P19/02

摘要： Disclosed in the present application are a class of compounds as JAK inhibitors and use thereof in the preparation of medicaments for treating JAK and TYK2 related diseases. Specifically, a compound represented by formula (I), an isomer thereof or a pharmaceutically acceptable salt thereof is disclosed.

公开(公告)号：US20210155621A1

公开(公告)日：2021-05-27

申请号：US17263416

申请日：2019-08-23

申请人： Zhuhai United Laboratories Co., Ltd.

发明人： Weiwei MAO ,  Wenyuan QIAN ,  Xuejian ZHENG ,  Guoping HU ,  Changqing WEI ,  Jian LI ,  Shuhui CHEN

IPC分类号： C07D471/04 ,  A61P19/02

摘要： Disclosed are a [1,2,4]triazolo[1,5-a]pyridine compound as JAK inhibitor and an application thereof in preparing a drug for treating a disease related to JAK or/and TYK2. Specifically, the present invention relates to a compound represented by formula (I), or an isomer or pharmaceutically acceptable salt thereof. (I)