公开(公告)号：US20230091250A1

公开(公告)日：2023-03-23

申请号：US17796613

申请日：2021-02-22

申请人： Zhuhai United Laboratories CO., LTD.

发明人： Weiwei MAO ,  Wenyuan QIAN ,  Changqing WEI ,  Liang FANG ,  Liwei MU ,  Shuhui CHEN

IPC分类号： C07D471/04 ,  A61P29/00 ,  A61P19/02

摘要： The present invention discloses the crystal forms as a JAK inhibitor and their application in the preparation of drugs for the treatment of JAK1 or/and TYK2 related diseases.

公开(公告)号：US20210070754A1

公开(公告)日：2021-03-11

申请号：US16966112

申请日：2019-01-31

申请人： ZHUHAI UNITED LABORATORIES CO., LTD.

发明人： Weiwei MAO ,  Hao WU ,  Xuejian ZHENG ,  Guoping HU ,  Changqing WEI ,  Jian LI ,  Shuhui CHEN

IPC分类号： C07D471/04 ,  C07D513/04 ,  A61P19/02

摘要： Disclosed in the present application are a class of compounds as JAK inhibitors and use thereof in the preparation of medicaments for treating JAK and TYK2 related diseases. Specifically, a compound represented by formula (I), an isomer thereof or a pharmaceutically acceptable salt thereof is disclosed.

公开(公告)号：US20210155621A1

公开(公告)日：2021-05-27

申请号：US17263416

申请日：2019-08-23

申请人： Zhuhai United Laboratories Co., Ltd.

发明人： Weiwei MAO ,  Wenyuan QIAN ,  Xuejian ZHENG ,  Guoping HU ,  Changqing WEI ,  Jian LI ,  Shuhui CHEN

IPC分类号： C07D471/04 ,  A61P19/02

摘要： Disclosed are a [1,2,4]triazolo[1,5-a]pyridine compound as JAK inhibitor and an application thereof in preparing a drug for treating a disease related to JAK or/and TYK2. Specifically, the present invention relates to a compound represented by formula (I), or an isomer or pharmaceutically acceptable salt thereof. (I)