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1.发明申请Synthetic pentacyclic triterpenoids and derivatives of betulinic acid and betulin 审中-公开合成五环三萜类化合物和桦木酸和桦木醇的衍生物公开(公告)号：US20070232577A1
公开(公告)日：2007-10-04
申请号：US11728284
申请日：2007-03-23
申请人： Ze-Qi Xu , Ali Koohang , Aye Aye Mar , Nathan Majewski , David Eiznhamer , Michael Flavin
发明人： Ze-Qi Xu , Ali Koohang , Aye Aye Mar , Nathan Majewski , David Eiznhamer , Michael Flavin
CPC分类号： C07J53/00
摘要： The present invention comprises small molecule inhibitors of cell proliferative conditions, in particular cancer and conditions associated with cancer. For example, associated malignancies include ovarian cancer, cervical cancer, breast cancer, colorectal cancer, and glioblastomas, among others. Accordingly, the compounds of the present invention are useful for treating, preventing, and/or inhibiting these diseases. Thus, the present invention also comprising pharmaceutical formulations comprising the compounds and methods of using the compounds and formulations to inhibit cancer and treat, prevent, or inhibit the foregoing diseases.
摘要翻译： 本发明包括细胞增殖状态的特别是癌症和与癌症有关的病症的小分子抑制剂。 例如，相关的恶性肿瘤包括卵巢癌，子宫颈癌，乳腺癌，结肠直肠癌和成胶质细胞瘤等。 因此，本发明的化合物可用于治疗，预防和/或抑制这些疾病。 因此，本发明还包括包含该化合物的药物制剂和使用该化合物和制剂抑制癌症并治疗，预防或抑制前述疾病的方法。
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2.发明申请Lupane-Type Triterpenoids Modified at 30-Position and Analogues Thereof 审中-公开Lupane型三萜类化合物在30位修饰及其类似物公开(公告)号：US20090062243A1
公开(公告)日：2009-03-05
申请号：US12171069
申请日：2008-07-10
申请人： Ali Koohang , Aye Aye Mar , Erika Szotek , Ze-Qi Xu , David A. Eiznhamer , Michael T. Flavin
发明人： Ali Koohang , Aye Aye Mar , Erika Szotek , Ze-Qi Xu , David A. Eiznhamer , Michael T. Flavin
CPC分类号： C07J53/00
摘要： The present invention comprises lupine-type triterpenoids that inhibit cell proliferations, in particular cancer and conditions associated with cancer. For example, associated malignancies include ovarian cancer, cervical cancer, breast cancer, colorectal cancer, and glioblastomas, among others. Accordingly, the compounds of the present invention are useful for treating, preventing, and/or inhibiting these diseases. Thus, the present invention also comprising pharmaceutical formulations comprising the compounds and methods of using the compounds and formulations to inhibit cancer and treat, prevent, or inhibit the foregoing diseases.
摘要翻译： 本发明包括抑制细胞增殖的羽扇蛋白型三萜类化合物，特别是与癌症相关的癌症和病症。 例如，相关的恶性肿瘤包括卵巢癌，子宫颈癌，乳腺癌，结肠直肠癌和成胶质细胞瘤等。 因此，本发明的化合物可用于治疗，预防和/或抑制这些疾病。 因此，本发明还包括包含该化合物的药物制剂和使用该化合物和制剂抑制癌症并治疗，预防或抑制前述疾病的方法。
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3.发明申请公开(公告)号：US20100144688A1
公开(公告)日：2010-06-10
申请号：US12634305
申请日：2009-12-09
申请人： Ali Koohang , Aye Aye Mar , Erika Szotek , Ze-Qi Xu , David A. Eiznhamer , Michael T. Flavin
发明人： Ali Koohang , Aye Aye Mar , Erika Szotek , Ze-Qi Xu , David A. Eiznhamer , Michael T. Flavin
摘要： The present invention comprises small molecule inhibitors of cell proliferative conditions, in particular cancer and conditions associated with cancer. For example, associated malignancies include ovarian cancer, cervical cancer, breast cancer, colorectal cancer, and glioblastomas, among others. Accordingly, the compounds of the present invention are useful for treating, preventing, and/or inhibiting these diseases. Thus, the present invention also comprises pharmaceutical formulations comprising the compounds and methods of using the compounds and formulations to inhibit cancer and treat, prevent, or inhibit the foregoing diseases.
摘要翻译： 本发明包括细胞增殖状态的特别是癌症和与癌症有关的病症的小分子抑制剂。 例如，相关的恶性肿瘤包括卵巢癌，子宫颈癌，乳腺癌，结肠直肠癌和成胶质细胞瘤等。 因此，本发明的化合物可用于治疗，预防和/或抑制这些疾病。 因此，本发明还包括包含该化合物的药物制剂以及使用该化合物和制剂抑制癌症并治疗，预防或抑制前述疾病的方法。
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