公开(公告)号：US20110251188A1

公开(公告)日：2011-10-13

申请号：US13128381

申请日：2009-10-25

申请人： Zhichao Zhang ,  Guiye Wu ,  Ting Song ,  Feibo Xie

发明人： Zhichao Zhang ,  Guiye Wu ,  Ting Song ,  Feibo Xie

IPC分类号： A61K31/541 ,  A61P35/00 ,  A61K31/403 ,  C08B37/16 ,  C07D209/94 ,  C07D417/10

CPC分类号： C07D209/70 ,  A61K31/403 ,  A61K31/54 ,  C07D405/12 ,  C07D409/12 ,  C08B37/0015

摘要： The present invention relates to acenaphtho heterocyclic compounds, cyclodextrin inclusion compounds and complexes thereof, and their uses in manufacturing the inhibitors of BH3 analogue, Bcl-2 family proteins. The acenaphtho heterocyclic compounds are obtained by introducing oxo-, thio-, carbonyl, ester or acyl in the 3-, 4- and 6-position of 8-oxo-8H-acenaphtho[1,2-b]pyrrole-9-carbonitrile, or further substituting 9-cyano with carboxyl, ester or amide. The compounds can simulate BH3-only protein, competitively binding and antagonizing Bcl-2, Bel-XL and Mcl-1 proteins in vitro or intracellular, to induce cell apoptosis. The cyclodextrin inclusion compounds and complexes can improve the effects. Therefore, they all can be used in the manufactures of anticancer compounds.

摘要翻译： 本发明涉及苊萘杂环化合物，环糊精包合物及其复合物，以及它们在制备BH3类似物Bcl-2家族蛋白抑制剂中的应用。 通过在8-氧代-8H-苊并[1,2-b]吡咯-9-腈的3-，4-和6-位引入氧代，硫代，羰基，酯或酰基，得到苊并杂环化合物 或进一步用羧基，酯或酰胺代替9-氰基。 该化合物可以模拟BH3蛋白，体外或细胞内竞争性结合和拮抗Bcl-2，Bel-XL和Mcl-1蛋白，诱导细胞凋亡。 环糊精包合物和配合物可以改善效果。 因此，它们都可用于抗癌化合物的制造。

公开(公告)号：US20100245360A1

公开(公告)日：2010-09-30

申请号：US12415538

申请日：2009-03-31

申请人： Ting Song ,  Vincent B. Ho

发明人： Ting Song ,  Vincent B. Ho

IPC分类号： G06T11/20

CPC分类号： G06T11/206 ,  A61B5/02007 ,  A61B6/00 ,  A61B6/469 ,  G06T7/246 ,  G06T7/66 ,  G06T11/203 ,  G06T11/40 ,  G06T2207/10016 ,  G06T2207/10076 ,  G06T2207/10088 ,  G06T2207/10132 ,  G06T2207/30048 ,  G06T2207/30241

摘要： A system and method for center point trajectory mapping includes a computer readable storage medium having stored thereon a computer program comprises instructions, which when executed by a computer, cause the computer to acquire a first plurality of images, each image comprising a masked portion. The instructions also cause the computer to locate a center point of the masked portion in each of the plurality of images and to plot a map based on variances in position of the center points from each other. The instructions further cause the computer to display the map on a display.

摘要翻译： 用于中心点轨迹映射的系统和方法包括其上存储有计算机程序的计算机可读存储介质，其包括指令，当由计算机执行时，指令使计算机获取第一多个图像，每个图像包括掩蔽部分。 指令还使得计算机在多个图像的每一个中定位掩蔽部分的中心点，并且基于中心点彼此位置的方差绘制地图。 这些说明进一步导致计算机在显示屏上显示地图。

公开(公告)号：US20110075902A1

公开(公告)日：2011-03-31

申请号：US12961159

申请日：2010-12-06

申请人： Ting Song ,  Vincent B. Ho

发明人： Ting Song ,  Vincent B. Ho

IPC分类号： G06K9/00 ,  G06T11/20

CPC分类号： A61B6/00 ,  A61B5/02007 ,  A61B5/742 ,  A61B6/469 ,  G06T7/0016 ,  G06T7/246 ,  G06T7/66 ,  G06T11/206 ,  G06T2200/24 ,  G06T2207/10072 ,  G06T2207/10132 ,  G06T2207/30048

摘要： A computer implemented method of mapping of multiple regional center point trajectory movements of cavity walls is provided in which images are acquired and a region-of-interest is identified in each of the images. The region-of-interest is divided into a plurality of distinct regions and a regional center point for each of the regions is located in the images. For each regional center point, a center point trajectory is determined based on variances in position of the center points from each other in the images. The center point trajectory of each regional center point is decomposed into radial and circumferential components so as to isolate radial component of the center point trajectory for each regional center point in each of the images and radial motion versus time curves are displayed for each regional center point based on the determined radial component for each regional center point in each of the images.

摘要翻译： 提供了一种映射空腔壁的多个区域中心点轨迹运动的计算机实现方法，其中获取图像，并且在每个图像中识别感兴趣区域。 感兴趣区域被分成多个不同的区域，并且每个区域的区域中心点位于图像中。 对于每个区域中心点，基于图像中的彼此的中心点的位置的方差确定中心点轨迹。 每个区域中心点的中心点轨迹被分解成径向和圆周分量，以便隔离每个图像中每个区域中心点的中心点轨迹的径向分量，并且针对每个区域中心点显示径向运动与时间曲线 基于每个图像中每个区域中心点的确定的径向分量。

公开(公告)号：US08659603B2

公开(公告)日：2014-02-25

申请号：US12415538

申请日：2009-03-31

申请人： Ting Song ,  Vincent B. Ho

发明人： Ting Song ,  Vincent B. Ho

IPC分类号： G06T11/20 ,  G06T11/40

CPC分类号： G06T11/206 ,  A61B5/02007 ,  A61B6/00 ,  A61B6/469 ,  G06T7/246 ,  G06T7/66 ,  G06T11/203 ,  G06T11/40 ,  G06T2207/10016 ,  G06T2207/10076 ,  G06T2207/10088 ,  G06T2207/10132 ,  G06T2207/30048 ,  G06T2207/30241

摘要： A system and method for center point trajectory mapping includes a computer readable storage medium having stored thereon a computer program comprises instructions, which when executed by a computer, cause the computer to acquire a first plurality of images, each image comprising a masked portion. The instructions also cause the computer to locate a center point of the masked portion in each of the plurality of images and to plot a map based on variances in position of the center points from each other. The instructions further cause the computer to display the map on a display.

摘要翻译： 用于中心点轨迹映射的系统和方法包括其上存储有计算机程序的计算机可读存储介质，其包括指令，当由计算机执行时，指令使计算机获取第一多个图像，每个图像包括掩蔽部分。 指令还使得计算机在多个图像的每一个中定位掩蔽部分的中心点，并且基于中心点彼此位置的方差绘制地图。 这些说明进一步导致计算机在显示屏上显示地图。

公开(公告)号：US20120008833A1

公开(公告)日：2012-01-12

申请号：US12833428

申请日：2010-07-09

申请人： Ting Song ,  Vincent B. Ho

发明人： Ting Song ,  Vincent B. Ho

IPC分类号： G06K9/00

CPC分类号： G06T7/0016 ,  G06T2207/10072 ,  G06T2207/10116 ,  G06T2207/10132 ,  G06T2207/20104 ,  G06T2207/30048

摘要： A system and method for center point trajectory mapping includes a computer readable storage medium having stored thereon a computer program comprises instructions, which when executed by a computer, cause the computer to obtain a first plurality of images, each image comprising an unmasked portion and a masked portion, and to calculate a center curve in the unmasked portion in each of the first plurality of images. The instructions further cause the computer to calculate a displacement of the center curve in each of the first plurality of images from a reference center curve, plot a map based on the calculated displacements, and display the map on a display.

摘要翻译： 用于中心点轨迹映射的系统和方法包括其上存储有计算机程序的计算机可读存储介质，包括指令，当由计算机执行时，指令使计算机获得第一多个图像，每个图像包括未屏蔽部分和 并且计算第一多个图像中的每一个中的未屏蔽部分中的中心曲线。 指令还使得计算机从参考中心曲线计算第一多个图像中的每一个中的中心曲线的位移，基于计算的位移绘制地图，并在显示器上显示地图。

公开(公告)号：US07889490B2

公开(公告)日：2011-02-15

申请号：US12545273

申请日：2009-08-21

申请人： Shyn-Ren Chen ,  Tsai-Kuei Cheng ,  Shi-Feng Wang ,  Ji-Peng Xu ,  Yong-Hua Chen ,  Li-Hong Huang ,  Ting Song ,  Chia-Nan Chien ,  Banks Chen

发明人： Shyn-Ren Chen ,  Tsai-Kuei Cheng ,  Shi-Feng Wang ,  Ji-Peng Xu ,  Yong-Hua Chen ,  Li-Hong Huang ,  Ting Song ,  Chia-Nan Chien ,  Banks Chen

IPC分类号： G06F1/16

CPC分类号： G06F1/183 ,  H05K7/1457 ,  H05K7/1492

摘要： A sever including a chassis, at least one first tray, at least one second tray, a power supply module, multiple input/output interface circuit boards, and multiple mother boards is provided. The first and second trays are slidably disposed in the chassis, and the first and second trays can be drawn out of the chassis in opposite directions. The power supply module is disposed on a bottom plate of the chassis. The input/output interface circuit boards are disposed on the first tray, respectively. The power supply module is located between two input/output interface circuit boards. Each input/output interface circuit board has multiple input/output interfaces. The mother boards are disposed on the second trays, respectively. The input/output interface circuit boards and the power supply module are correspondingly electrically connected to the mother boards.

摘要翻译： 提供包括机箱，至少一个第一托盘，至少一个第二托盘，电源模块，多个输入/输出接口电路板和多个母板的服务器。 第一和第二托盘可滑动地设置在底盘中，并且第一和第二托盘可以在相反的方向被拉出底盘。 电源模块设置在底盘的底板上。 输入/输出接口电路板分别设置在第一托盘上。 电源模块位于两个输入/输出接口电路板之间。 每个输入/输出接口电路板有多个输入/输出接口。 母板分别设置在第二个托盘上。 输入/输出接口电路板和电源模块相应地电连接到母板。

公开(公告)号：US08014144B2

公开(公告)日：2011-09-06

申请号：US12542725

申请日：2009-08-18

申请人： Tsai-Kuei Cheng ,  Yong-Liang Hu ,  Ji-Peng Xu ,  Shi-Feng Wang ,  Shyn-Ren Chen ,  Chia-Nan Chien ,  Banks Chen ,  Ting Song ,  Ling-Yi Zhang

发明人： Tsai-Kuei Cheng ,  Yong-Liang Hu ,  Ji-Peng Xu ,  Shi-Feng Wang ,  Shyn-Ren Chen ,  Chia-Nan Chien ,  Banks Chen ,  Ting Song ,  Ling-Yi Zhang

IPC分类号： G06F1/16

CPC分类号： G06F1/187

摘要： A server device with a storage array module is provided. The server device includes a chassis, a motherboard module, and a storage array module. The motherboard module and the storage array module are disposed in the chassis. The storage array module includes a first tray removably disposed in the chassis, a hard disk back panel fixed to a bottom of the first tray, and several hard disks hot-pluggably disposed in the first tray. The hard disk back panel is electrically connected to the motherboard module, and the hard disks are electrically connected to the hard disk back panel and driven to move into/out the chassis with the first tray.

摘要翻译： 提供了具有存储阵列模块的服务器设备。 服务器设备包括机箱，主板模块和存储阵列模块。 主板模块和存储阵列模块设置在底盘中。 存储阵列模块包括可移除地布置在底盘中的第一托盘，固定到第一托盘的底部的硬盘后面板和可热插拔地设置在第一托盘中的几个硬盘。 硬盘后面板电连接到主板模块，并且硬盘电连接到硬盘后面板并被驱动以与第一托盘移入/移出机箱。

公开(公告)号：US20100265650A1

公开(公告)日：2010-10-21

申请号：US12545273

申请日：2009-08-21

申请人： SHYN-REN CHEN ,  Tsai-Kuei Cheng ,  Shi-Feng Wang ,  Ji-Peng Xu ,  Yong-Hua Chen ,  Li-Hong Huang ,  Ting Song ,  Chia-Nan Chien ,  Banks Chen

发明人： SHYN-REN CHEN ,  Tsai-Kuei Cheng ,  Shi-Feng Wang ,  Ji-Peng Xu ,  Yong-Hua Chen ,  Li-Hong Huang ,  Ting Song ,  Chia-Nan Chien ,  Banks Chen

IPC分类号： G06F1/16

CPC分类号： G06F1/183 ,  H05K7/1457 ,  H05K7/1492

摘要： A sever including a chassis, at least one first tray, at least one second tray, a power supply module, multiple input/output interface circuit boards, and multiple mother boards is provided. The first and second trays are slidably disposed in the chassis, and the first and second trays can be drawn out of the chassis in opposite directions. The power supply module is disposed on a bottom plate of the chassis. The input/output interface circuit boards are disposed on the first tray, respectively. The power supply module is located between two input/output interface circuit boards. Each input/output interface circuit board has multiple input/output interfaces. The mother boards are disposed on the second trays, respectively. The input/output interface circuit boards and the power supply module are correspondingly electrically connected to the mother boards.

摘要翻译： 提供包括机箱，至少一个第一托盘，至少一个第二托盘，电源模块，多个输入/输出接口电路板和多个母板的服务器。 第一和第二托盘可滑动地设置在底盘中，并且第一和第二托盘可以在相反的方向被拉出底盘。 电源模块设置在底盘的底板上。 输入/输出接口电路板分别设置在第一托盘上。 电源模块位于两个输入/输出接口电路板之间。 每个输入/输出接口电路板有多个输入/输出接口。 母板分别设置在第二个托盘上。 输入/输出接口电路板和电源模块相应地电连接到母板。

公开(公告)号：US08487933B2

公开(公告)日：2013-07-16

申请号：US12961159

申请日：2010-12-06

申请人： Ting Song ,  Vincent B. Ho

发明人： Ting Song ,  Vincent B. Ho

IPC分类号： G06T11/20 ,  G06K9/00

CPC分类号： A61B6/00 ,  A61B5/02007 ,  A61B5/742 ,  A61B6/469 ,  G06T7/0016 ,  G06T7/246 ,  G06T7/66 ,  G06T11/206 ,  G06T2200/24 ,  G06T2207/10072 ,  G06T2207/10132 ,  G06T2207/30048

摘要： A computer implemented method of mapping of multiple regional center point trajectory movements of cavity walls is provided in which images are acquired and a region-of-interest is identified in each of the images. The region-of-interest is divided into a plurality of distinct regions and a regional center point for each of the regions is located in the images. For each regional center point, a center point trajectory is determined based on variances in position of the center points from each other in the images. The center point trajectory of each regional center point is decomposed into radial and circumferential components so as to isolate radial component of the center point trajectory for each regional center point in each of the images and radial motion versus time curves are displayed for each regional center point based on the determined radial component for each regional center point in each of the images.

摘要翻译： 提供了一种映射空腔壁的多个区域中心点轨迹运动的计算机实现方法，其中获取图像，并且在每个图像中识别感兴趣区域。 感兴趣区域被分成多个不同的区域，并且每个区域的区域中心点位于图像中。 对于每个区域中心点，基于图像中的彼此的中心点的位置的方差确定中心点轨迹。 每个区域中心点的中心点轨迹被分解成径向和圆周分量，以便隔离每个图像中每个区域中心点的中心点轨迹的径向分量，并且针对每个区域中心点显示径向运动与时间曲线 基于每个图像中每个区域中心点的确定的径向分量。

公开(公告)号：US20130090946A1

公开(公告)日：2013-04-11

申请号：US13253853

申请日：2011-10-05

申请人： Thomas Kwok-Fah Foo ,  Robert David Darrow ,  Kenji Suzuki ,  Sandeep Narendra Gupta ,  Rakesh Mullick ,  Vivek Vaidya ,  Xiaodong Tao ,  Ting Song

发明人： Thomas Kwok-Fah Foo ,  Robert David Darrow ,  Kenji Suzuki ,  Sandeep Narendra Gupta ,  Rakesh Mullick ,  Vivek Vaidya ,  Xiaodong Tao ,  Ting Song

IPC分类号： G06Q50/24

CPC分类号： G06Q10/06 ,  G06Q50/22

摘要： An imaging workflow system includes a workstation for acquiring patient information and requesting a patient scan. The request for a patient scan includes scan information for performing the scan. A registration module receives the scan information and the patient information. The registration module automatically schedules the patient scan based on the scan information and the patient information. The registration module determines an imaging protocol based on the patient information and the scan information. An imaging module within an imaging system receives the imaging protocol. The imaging module automatically sets scan parameters based on the imaging protocol. The imaging system scans the patient based on the scan parameters to acquire image data. A user interface controls the patient scan. The user interface includes a display to display images generated from the acquired image data.

摘要翻译： 成像工作流系统包括用于获取患者信息并请求病人扫描的工作站。 患者扫描的请求包括用于执行扫描的扫描信息。 注册模块接收扫描信息和患者信息。 注册模块根据扫描信息和患者信息自动安排患者扫描。 注册模块基于患者信息和扫描信息来确定成像协议。 成像系统内的成像模块接收成像协议。 成像模块根据成像协议自动设置扫描参数。 成像系统基于扫描参数扫描患者以获取图像数据。 用户界面控制病人扫描。 用户界面包括用于显示从所获取的图像数据生成的图像的显示器。