公开(公告)号：US08395768B2

公开(公告)日：2013-03-12

申请号：US12772161

申请日：2010-04-30

申请人： Zhiyong Li ,  David A. Fattal ,  Jingjing Li ,  R. Stanley Williams

发明人： Zhiyong Li ,  David A. Fattal ,  Jingjing Li ,  R. Stanley Williams

IPC分类号： G01J3/44

CPC分类号： G01J3/44 ,  G01J3/1895 ,  G01N21/658

摘要： A scattering spectroscopy apparatus, system and method employ guided mode resonance (GMR) and a GMR grating. The apparatus includes a GMR grating having a subwavelength grating, and an optical detector configured to receive a portion of a scattered signal produced by an interaction between an excitation signal and an analyte associated with a surface of the GMR grating. A propagation direction of the received portion of the scattered signal is substantially different from a propagation direction of a GMR-coupled portion of the excitation signal within the GMR grating. The system includes the apparatus and an optical source. The method includes exciting a GMR in a GMR grating, interacting a GMR-coupled portion of the excitation signal with an analyte to produce a scattered signal and detecting a portion of the scattered signal.

摘要翻译： 散射光谱装置，系统和方法采用导模共振（GMR）和GMR光栅。 该装置包括具有亚波长光栅的GMR光栅和配置成接收由激发信号与与GMR光栅的表面相关联的分析物之间的相互作用产生的散射信号的一部分的光学检测器。 散射信号的接收部分的传播方向与GMR光栅内的激励信号的GMR耦合部分的传播方向基本上不同。 该系统包括该装置和光源。 该方法包括激励GMR光栅中的GMR，将激发信号的GMR耦合部分与分析物相互作用以产生散射信号并检测散射信号的一部分。

公开(公告)号：US20110267611A1

公开(公告)日：2011-11-03

申请号：US12772161

申请日：2010-04-30

申请人： Zhiyong Li ,  David A. Fattal ,  Jingjing Li ,  R. Stanley Williams

发明人： Zhiyong Li ,  David A. Fattal ,  Jingjing Li ,  R. Stanley Williams

IPC分类号： G01J3/44 ,  G01J3/00

CPC分类号： G01J3/44 ,  G01J3/1895 ,  G01N21/658

摘要： A scattering spectroscopy apparatus, system and method employ guided mode resonance (GMR) and a GMR grating. The apparatus includes a GMR grating having a subwavelength grating, and an optical detector configured to receive a portion of a scattered signal produced by an interaction between an excitation signal and an analyte associated with a surface of the GMR grating. A propagation direction of the received portion of the scattered signal is substantially different from a propagation direction of a GMR-coupled portion of the excitation signal within the GMR grating. The system includes the apparatus and an optical source. The method includes exciting a GMR in a GMR grating, interacting a GMR-coupled portion of the excitation signal with an analyte to produce a scattered signal and detecting a portion of the scattered signal.

摘要翻译： 散射光谱装置，系统和方法采用导模共振（GMR）和GMR光栅。 该装置包括具有亚波长光栅的GMR光栅和配置成接收由激发信号与与GMR光栅的表面相关联的分析物之间的相互作用产生的散射信号的一部分的光学检测器。 散射信号的接收部分的传播方向与GMR光栅内的激励信号的GMR耦合部分的传播方向基本上不同。 该系统包括该装置和光源。 该方法包括激励GMR光栅中的GMR，将激发信号的GMR耦合部分与分析物相互作用以产生散射信号并检测散射信号的一部分。

公开(公告)号：US08542355B2

公开(公告)日：2013-09-24

申请号：US13383078

申请日：2009-07-08

申请人： David A. Fattal ,  Jingjing Li ,  Zhiyong Li ,  Shih-Yuan Wang

发明人： David A. Fattal ,  Jingjing Li ,  Zhiyong Li ,  Shih-Yuan Wang

IPC分类号： G01J3/44

CPC分类号： G01N21/658 ,  B82Y20/00

摘要： A light amplifying device for surface enhanced Raman spectroscopy is disclosed herein. The device includes a dielectric layer having two opposed surfaces. A refractive index of the dielectric layer is higher than a refractive index of a material or environment directly adjacent thereto. At least one opening is formed in one of the two opposed surfaces of the dielectric layer, and at least one nano-antenna is established on the one of the two opposed surfaces of the dielectric layer. A gain region is positioned in the dielectric layer or adjacent to another of the two opposed surfaces of the dielectric layer.

摘要翻译： 本文公开了一种用于表面增强拉曼光谱的光放大装置。 该装置包括具有两个相对表面的电介质层。 电介质层的折射率高于与其直接相邻的材料或环境的折射率。 至少一个开口形成在电介质层的两个相对表面之一中，并且至少一个纳米天线被建立在电介质层的两个相对表面之一上。 增益区域位于电介质层中或邻近电介质层的两个相对表面中的另一个。

公开(公告)号：US20120013903A1

公开(公告)日：2012-01-19

申请号：US13258391

申请日：2009-07-30

申请人： Huei Pei Kuo ,  Shih-Yuan Wang ,  David A. Fattal ,  Jingjing Li ,  Nobuhiko Kobayashi ,  Zhiyong Li

发明人： Huei Pei Kuo ,  Shih-Yuan Wang ,  David A. Fattal ,  Jingjing Li ,  Nobuhiko Kobayashi ,  Zhiyong Li

IPC分类号： G01J3/44 ,  B82Y20/00 ,  B82B1/00

CPC分类号： G01N21/658

摘要： Embodiments of the present invention are directed to systems for performing surface-enhanced Raman spectroscopy. In one embodiment, a system (100, 400, 600, 800, 900, 950) for performing Raman spectroscopy comprises a substrate (102) substantially transparent to a range of wavelengths of electromagnetic radiation and a plurality of nanowires (104, 602) disposed on a surface of the substrate. The nanowires are substantially transparent to the range of wavelengths of electromagnetic radiation. The system includes a material disposed on each of the nanowires. The electromagnetic radiation is transmitted within the substrate, into the nanowires, and emitted from the ends of the nanowires to produce enhanced Raman scattered light from molecules located on or in proximity to the material.

摘要翻译： 本发明的实施例涉及用于进行表面增强拉曼光谱的系统。 在一个实施例中，用于执行拉曼光谱的系统（100,400,600,800,900,950）包括对电磁辐射的波长范围基本上透明的基底（102）和设置的多个纳米线（104,602） 在基板的表面上。 纳米线对于电磁辐射的波长范围基本上是透明的。 该系统包括设置在每个纳米线上的材料。 电磁辐射在衬底内传输到纳米线中，并从纳米线的端部发射，以产生来自位于材料上或附近的分子的增强的拉曼散射光。

公开(公告)号：US08687186B2

公开(公告)日：2014-04-01

申请号：US13383387

申请日：2009-07-30

申请人： Shih-Yuan Wang ,  Jingjing Li ,  Huei Pei Kuo ,  David A. Fattal ,  Nobuhiko Kobayashi ,  Zhiyong Li

发明人： Shih-Yuan Wang ,  Jingjing Li ,  Huei Pei Kuo ,  David A. Fattal ,  Nobuhiko Kobayashi ,  Zhiyong Li

IPC分类号： G01J3/44

CPC分类号： G01N21/658 ,  B82Y15/00 ,  G01J3/44

摘要： Embodiments of the present invention are directed to nanowire-based systems for performing surface-enhanced Raman spectroscopy. In one embodiment, a system comprises a substrate having a surface and a plurality of tapered nanowires disposed on the surface. Each nanowire has a tapered end directed away from the surface. The system also includes a plurality of nanoparticles disposed near the tapered end of each nanowire. When each nanowire is illuminated with light of a pump wavelength, Raman excitation light is emitted from the tapered end of the nanowire to interact with the nanoparticles and produce enhanced Raman scattered light from molecules located in close proximity to the nanoparticles.

摘要翻译： 本发明的实施方案涉及用于进行表面增强拉曼光谱的基于纳米线的系统。 在一个实施例中，系统包括具有设置在表面上的表面和多个锥形纳米线的基板。 每个纳米线具有远离表面的锥形端。 该系统还包括设置在每个纳米线的锥形端附近的多个纳米颗粒。 当每个纳米线被泵浦波长的光照射时，拉曼激发光从纳米线的锥形端发射以与纳米颗粒相互作用，并从位于紧邻纳米颗粒的分子产生增强的拉曼散射光。

公开(公告)号：US20120113418A1

公开(公告)日：2012-05-10

申请号：US13383078

申请日：2009-07-08

申请人： David A. Fattal ,  Jingjing Li ,  Zhiyong Li ,  Shih-Yuan Wang

发明人： David A. Fattal ,  Jingjing Li ,  Zhiyong Li ,  Shih-Yuan Wang

IPC分类号： G01J3/44 ,  H01L21/20 ,  H01L33/06 ,  B82Y40/00 ,  B82Y99/00

CPC分类号： G01N21/658 ,  B82Y20/00

摘要： A light amplifying device for surface enhanced Raman spectroscopy is disclosed herein. The device includes a dielectric layer having two opposed surfaces. A refractive index of the dielectric layer is higher than a refractive index of a material or environment directly adjacent thereto. At least one opening is formed in one of the two opposed surfaces of the dielectric layer, and at least one nano-antenna is established on the one of the two opposed surfaces of the dielectric layer. A gain region is positioned in the dielectric layer or adjacent to another of the two opposed surfaces of the dielectric layer.

摘要翻译： 本文公开了一种用于表面增强拉曼光谱的光放大装置。 该装置包括具有两个相对表面的电介质层。 电介质层的折射率高于与其直接相邻的材料或环境的折射率。 至少一个开口形成在电介质层的两个相对表面之一中，并且至少一个纳米天线被建立在电介质层的两个相对表面之一上。 增益区域位于电介质层中或邻近电介质层的两个相对表面中的另一个。

公开(公告)号：US20120113419A1

公开(公告)日：2012-05-10

申请号：US13383387

申请日：2009-07-30

申请人： Shih-Yuan Wang ,  Jingjing Li ,  Huei Pei Kuo ,  David A. Fattal ,  Nobuhiko Kobayashi ,  Zhiyong Li

发明人： Shih-Yuan Wang ,  Jingjing Li ,  Huei Pei Kuo ,  David A. Fattal ,  Nobuhiko Kobayashi ,  Zhiyong Li

IPC分类号： G01J3/44 ,  B82Y99/00

CPC分类号： G01N21/658 ,  B82Y15/00 ,  G01J3/44

摘要： Embodiments of the present invention are directed to nanowire-based systems for performing surface-enhanced Raman spectroscopy. In one embodiment, a system comprises a substrate (102) having a surface and a plurality of tapered nanowires (104) disposed on the surface. Each nanowire has a tapered end directed away from the surface. The system also includes a plurality of nanoparticles (110) disposed near the tapered end of each nanowire. When each nanowire is illuminated with light of a pump wavelength, Raman excitation light is emitted from the tapered end of the nanowire to interact with the nanoparticles and produce enhanced Raman scattered light from molecules located in close proximity to the nanoparticles.

摘要翻译： 本发明的实施方案涉及用于进行表面增强拉曼光谱的基于纳米线的系统。 在一个实施例中，系统包括具有表面的基板（102）和设置在表面上的多个锥形纳米线（104）。 每个纳米线具有远离表面的锥形端。 该系统还包括在每个纳米线的锥形端附近设置的多个纳米颗粒（110）。 当每个纳米线被泵浦波长的光照射时，拉曼激发光从纳米线的锥形端发射以与纳米颗粒相互作用，并从位于紧邻纳米颗粒的分子产生增强的拉曼散射光。

公开(公告)号：US20120300202A1

公开(公告)日：2012-11-29

申请号：US13383385

申请日：2009-07-22

申请人： David A. Fattal ,  Jingjing Li ,  Zhiyong Li ,  Shih-Yuan Wang

发明人： David A. Fattal ,  Jingjing Li ,  Zhiyong Li ,  Shih-Yuan Wang

IPC分类号： G01J3/44 ,  B82Y15/00

CPC分类号： G01N21/658

摘要： An autonomous light amplifying device for surface enhanced Raman spectroscopy includes a dielectric layer, at least one laser cavity defined by at least one light confining mechanism formed in the dielectric layer, at least one nano-antenna established on the dielectric layer in proximity to the at least one laser cavity, and a gain region positioned in the dielectric layer or adjacent to the dielectric layer.

摘要翻译： 用于表面增强拉曼光谱的自主光放大装置包括电介质层，至少一个激光腔，其由形成在电介质层中的至少一个限光机构限定，至少一个在电介质层上建立的纳米天线邻近于 至少一个激光腔，以及位于所述介电层中或与所述电介质层相邻的增益区。

公开(公告)号：US20130188172A1

公开(公告)日：2013-07-25

申请号：US13877319

申请日：2010-10-11

申请人： Kai-Mei Camilla Fu ,  Paul Edward Barclay ,  David A. Fattal ,  Jingjing Li ,  Raymond G. Beausoleil

发明人： Kai-Mei Camilla Fu ,  Paul Edward Barclay ,  David A. Fattal ,  Jingjing Li ,  Raymond G. Beausoleil

IPC分类号： G01N21/03

CPC分类号： G01N21/0303 ,  B01L3/502715 ,  B01L2200/0668 ,  B01L2300/0816 ,  B01L2300/168 ,  G01N2015/1415

摘要： In one embodiment, an optical system includes a microfluidic chip assembly. The microfluidic chip assembly includes a first structure that provides a first wall of a fluid channel. A second structure provides a second wall of the fluid channel. The second structure includes a diffraction grating configured to provide, in the presence of incident light of a wavelength band of interest on a first surface of the second structure, a plurality of regions of high intensity light within the fluid channel.

摘要翻译： 在一个实施例中，光学系统包括微流体芯片组件。 微流体芯片组件包括提供流体通道的第一壁的第一结构。 第二结构提供了流体通道的第二壁。 第二结构包括衍射光栅，被配置成在存在感兴趣的波长带的入射光存在于第二结构的第一表面上时，在流体通道内提供高强度光的多个区域。

公开(公告)号：US08385000B2

公开(公告)日：2013-02-26

申请号：US13087776

申请日：2011-04-15

申请人： Jingjing Li ,  David A. Fattal ,  Marco Fiorentino ,  Raymond G. Beausoleil

发明人： Jingjing Li ,  David A. Fattal ,  Marco Fiorentino ,  Raymond G. Beausoleil

IPC分类号： G02B3/00

CPC分类号： G02B27/58 ,  G02B5/1809 ,  G02B5/1876 ,  G02B27/4238 ,  G02B27/425

摘要： A lens and a method of forming a lens are included. A lens can include a plurality of concentric rings formed from a dielectric material interleaved by a plurality of gaps separating the plurality of concentric rings.

摘要翻译： 包括透镜和形成透镜的方法。 透镜可以包括由隔离多个同心环的多个间隙交错的介电材料形成的多个同心环。