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公开(公告)号:US20210379023A1
公开(公告)日:2021-12-09
申请号:US17392569
申请日:2021-08-03
申请人: Zoetis Services LLC
IPC分类号: A61K31/422 , A61K47/10 , A61K47/12 , A61K47/14 , A61K9/00 , A01N43/90 , A61K47/08 , A61K47/32 , A61K45/06 , A61K47/22
摘要: The invention describes a long-acting composition comprising a spiro-azetidine isoxazoline of Formula (1) or (2) wherein R1a, R1b, R1c and R2 are as described herein, and stereoisomers thereof. The composition is a veterinary composition and also comprises a glycol ether and at least one veterinarily acceptable solvent, and optionally, at least one precipitation inhibitor, antioxidant and additional veterinary agent, and any mixture thereof. The invention also includes a method of treating an animal with a parasitic infestation by administering the long-acting composition to the animal in need thereof.
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公开(公告)号:US20160083435A9
公开(公告)日:2016-03-24
申请号:US13864658
申请日:2013-04-17
发明人: Robert M. Lohse , Patrick F. M. Meeus , Jason J. Millership , Zhichang Xu , Richard Thomas Marconi , Christopher G. Earnhart
IPC分类号: C07K14/20
CPC分类号: C07K14/20 , A61K39/0225 , A61K2039/552 , A61K2039/55505 , A61K2039/70 , C07K2319/00
摘要: The instant invention provides an immunogenic composition comprising an antigenic fragment of OspA protein of Borrelia burgdorferi and a chimeric protein containing antigenic fragments of different phylotypes of OspC protein of Borrelia burgdorferi. Vaccines incorporating the immunogenic composition of the invention, as well as methods of preventing Lyme disease in dogs and/or protecting dogs from Lyme disease using the vaccines are also provided.
摘要翻译: 本发明提供了一种免疫原性组合物,其包含布氏疏螺旋体的OspA蛋白的抗原性片段和含有不同的布氏疏螺旋体OspC蛋白的不同致病型的抗原片段的嵌合蛋白质。 还提供了掺入本发明的免疫原性组合物的疫苗,以及使用疫苗在狗和/或使用莱姆病保护狗来预防莱姆病的方法。
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公开(公告)号:US09226928B2
公开(公告)日:2016-01-05
申请号:US14426264
申请日:2013-09-04
申请人: Zoetis Services LLC
IPC分类号: A61K31/506 , A61K31/365 , A61K31/422 , A01N43/90 , A61K31/505
CPC分类号: A61K31/506 , A01N43/90 , A61K31/365 , A61K31/422 , A61K31/505 , A01N37/40 , A01N43/54 , A01N47/20 , A01N47/34 , A01N51/00
摘要: The present invention relates to a novel antiparasitic composition comprising an effective amount of a) a Formula (1) compound, wherein R1a, R1b, R1c, R2, R3, R4, and n are as defined herein, stereoisomer thereof, or a pharmaceutical or veterinary acceptable salt thereof, b) a macrocyclic lactone or derivative thereof and c) optionally, at least one additional veterinary agent, and further comprising at least one veterinary or pharmaceutical acceptable carrier; and a method of treating an animal with a parasitic infection, by administering an effective amount of said composition to the animal in need thereof.
摘要翻译: 本发明涉及一种新的抗寄生虫剂组合物,其包含有效量的a)式(1)化合物,其中R1a,R1b,R1c,R2,R3,R4和n如本文所定义,其立体异构体,或药物或 兽医学可接受的盐,b)大环内酯或其衍生物,和c)任选的至少一种另外的兽药,并且还包含至少一种兽药或药学上可接受的载体; 以及通过向有需要的动物施用有效量的所述组合物来治疗具有寄生虫感染的动物的方法。
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公开(公告)号:US20160081986A1
公开(公告)日:2016-03-24
申请号:US14888972
申请日:2014-05-19
申请人: Zoetis Services LLC
CPC分类号: A61K31/422 , A01N43/90 , A61K9/0017 , A61K45/06 , A61K47/08 , A61K47/10 , A61K47/12 , A61K47/14 , A61K47/22 , A61K47/32 , A01N25/02
摘要: The invention describes a long-acting composition comprising a spiro-azetidine isoxazoline of Formula (1) or (2) wherein R1a, R1b, R1c and R2 are as described herein, and stereoisomers thereof. The composition is a veterinary composition and also comprises a glycol ether and at least one veterinarily acceptable solvent, and optionally, at least one precipitation inhibitor, antioxidant and additional veterinary agent, and any mixture thereof. The invention also includes a method of treating an animal with a parasitic infestation by administering the long-acting composition to the animal in need thereof.
摘要翻译: 本发明描述了一种长效组合物,其包含式(1)或(2)的螺 - 氮杂环丁烷异恶唑啉,其中R1a,R1b,R1c和R2如本文所述,及其立体异构体。 该组合物是兽用组合物,还包含二醇醚和至少一种兽医学上可接受的溶剂,以及任选的至少一种沉淀抑制剂,抗氧化剂和另外的兽用药剂及其任何混合物。 本发明还包括通过向有需要的动物施用长效组合物来治疗具有寄生虫感染的动物的方法。
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公开(公告)号:US20230414576A1
公开(公告)日:2023-12-28
申请号:US18462535
申请日:2023-09-07
申请人: Zoetis Services LLC
IPC分类号: A61K31/422 , A61K47/10 , A61K47/12 , A61K47/14 , A61K9/00 , A01N43/90 , A61K47/08 , A61K47/32 , A61K45/06 , A61K47/22
CPC分类号: A61K31/422 , A61K47/10 , A61K47/12 , A61K47/14 , A61K47/22 , A01N43/90 , A61K47/08 , A61K47/32 , A61K45/06 , A61K9/0017
摘要: The invention describes a long-acting composition comprising a spiro-azetidine isoxazoline of Formula (1) or (2)
wherein R1a, R1b, R1c and R2 are as described herein, and stereoisomers thereof. The composition is a veterinary composition and also comprises a glycol ether and at least one veterinarily acceptable solvent, and optionally, at least one precipitation inhibitor, antioxidant and additional veterinary agent, and any mixture thereof. The invention also includes a method of treating an animal with a parasitic infestation by administering the long-acting composition to the animal in need thereof.-
公开(公告)号:US09265771B2
公开(公告)日:2016-02-23
申请号:US14370239
申请日:2012-12-20
申请人: Zoetis Services LLC
IPC分类号: A61K31/546 , A61K45/06 , A61K31/43 , A61K31/65 , A61K31/7052
CPC分类号: A61K31/546 , A61K31/43 , A61K31/65 , A61K31/7052 , A61K45/06 , Y02A50/401 , A61K2300/00
摘要: The present invention provides a method for treating Lyme disease and/or a Borrelia infection in animals comprising administering to an animal in need thereof a therapeutically effective amount of cefovecin.
摘要翻译: 本发明提供了一种用于治疗动物中的莱姆病和/或疏螺旋体感染的方法,包括向有需要的动物施用治疗有效量的头孢维。。
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