Spirocyclic isoxazoline parasiticidal combinations
    3.
    发明授权
    Spirocyclic isoxazoline parasiticidal combinations 有权
    螺环异恶唑啉杀虫剂组合

    公开(公告)号:US09226928B2

    公开(公告)日:2016-01-05

    申请号:US14426264

    申请日:2013-09-04

    摘要: The present invention relates to a novel antiparasitic composition comprising an effective amount of a) a Formula (1) compound, wherein R1a, R1b, R1c, R2, R3, R4, and n are as defined herein, stereoisomer thereof, or a pharmaceutical or veterinary acceptable salt thereof, b) a macrocyclic lactone or derivative thereof and c) optionally, at least one additional veterinary agent, and further comprising at least one veterinary or pharmaceutical acceptable carrier; and a method of treating an animal with a parasitic infection, by administering an effective amount of said composition to the animal in need thereof.

    摘要翻译: 本发明涉及一种新的抗寄生虫剂组合物,其包含有效量的a)式(1)化合物,其中R1a,R1b,R1c,R2,R3,R4和n如本文所定义,其立体异构体,或药物或 兽医学可接受的盐,b)大环内酯或其衍生物,和c)任选的至少一种另外的兽药,并且还包含至少一种兽药或药学上可接受的载体; 以及通过向有需要的动物施用有效量的所述组合物来治疗具有寄生虫感染的动物的方法。

    LONG-ACTING SPIRO-ISOXAZOLINE ANTIPARASITIC COMPOSITIONS
    4.
    发明申请
    LONG-ACTING SPIRO-ISOXAZOLINE ANTIPARASITIC COMPOSITIONS 审中-公开
    长效螺旋 - 异山梨醇抗坏血酸组合物

    公开(公告)号:US20160081986A1

    公开(公告)日:2016-03-24

    申请号:US14888972

    申请日:2014-05-19

    摘要: The invention describes a long-acting composition comprising a spiro-azetidine isoxazoline of Formula (1) or (2) wherein R1a, R1b, R1c and R2 are as described herein, and stereoisomers thereof. The composition is a veterinary composition and also comprises a glycol ether and at least one veterinarily acceptable solvent, and optionally, at least one precipitation inhibitor, antioxidant and additional veterinary agent, and any mixture thereof. The invention also includes a method of treating an animal with a parasitic infestation by administering the long-acting composition to the animal in need thereof.

    摘要翻译: 本发明描述了一种长效组合物,其包含式(1)或(2)的螺 - 氮杂环丁烷异恶唑啉,其中R1a,R1b,R1c和R2如本文所述,及其立体异构体。 该组合物是兽用组合物,还包含二醇醚和至少一种兽医学上可接受的溶剂,以及任选的至少一种沉淀抑制剂,抗氧化剂和另外的兽用药剂及其任何混合物。 本发明还包括通过向有需要的动物施用长效组合物来治疗具有寄生虫感染的动物的方法。