公开(公告)号：US07897161B2

公开(公告)日：2011-03-01

申请号：US10516657

申请日：2002-11-12

申请人： Hajime Yamada ,  Akira Yamada

发明人： Hajime Yamada ,  Akira Yamada

IPC分类号： A61K8/00

CPC分类号： A61K47/36 ,  A61K31/56 ,  A61K47/26 ,  A61K47/40 ,  A61K47/6951 ,  B82Y5/00

摘要： An external medicine for treating dermatitis wherein an adrenocortical steroid is included by a cyclodextrin; and 0.025 to 0.5% by weight of the adrenocortical steroid, 0.2 to 30% by weight of the cyclodextrin, and 0.5 to 55% by weight of dextran or pullulan are dissolved in an aqueous solution containing polysaccharide; and 0.5 to 55% by weight of xyloglucan, trehalose, laminaran, krestin, and pectin are blended. Grape sugar, mutan, lentinan, sodium chloride, and potassium chloride are comprised in the medicine. The medicine has a higher cure effect on atopic dermatitis and psoriasis vulgaris.

摘要翻译： 一种治疗皮炎的外用药物，其中由环糊精包括肾上腺皮质类固醇; 和0.025〜0.5重量％的肾上腺皮质类固醇，0.2〜30重量％的环糊精和0.5〜55重量％的葡聚糖或支链淀粉溶解于含有多糖的水溶液中; 并配合0.5〜55重量％的木葡聚糖，海藻糖，层流蛋白，克雷斯汀和果胶。 葡萄糖，变应素，香菇多糖，氯化钠和氯化钾包含在药物中。 该药对特应性皮炎和寻常型牛皮癣具有较高的治疗效果。

公开(公告)号：US5885978A

公开(公告)日：1999-03-23

申请号：US626963

申请日：1996-04-03

申请人： Hajime Yamada ,  Akira Yamada

发明人： Hajime Yamada ,  Akira Yamada

IPC分类号： A61K9/08 ,  A61K31/00 ,  A61K31/57 ,  A61K31/573 ,  A61K47/36 ,  A61K47/40 ,  A61K47/48 ,  A61P17/00 ,  A61P29/00 ,  A61K31/56

CPC分类号： B82Y5/00 ,  A61K47/48969

摘要： The present invention provides an external therapeutic composition for dermatitis comprising an aqueous solution including a therapeutically effective amount of an adrenal cortical steroid, a cyclodextrin, polysaccharides, and a carrier such as water, prepared by clathrating the adrenal cortical steroid in the cyclodextrin using a homomixer to form a clathrate, and adding the clathrate to an aqueous solution of polysaccharides, while being stirred uniformly, to dissolve the clathrate in the aqueous solution, as well as a method for the treatment of dermatitis in a mammalian subject, which comprises administering to said subject a therapeupically effective amount of the external therapeutic composition for dermatitis described above. The external therapeutic composition for dermatitis according to the present invention is extremely safe and can cure dermatitis such as an atopic dermatitis or the like without side effects.

摘要翻译： 本发明提供了一种外用皮炎治疗组合物，其包含水溶液，其包含治疗有效量的肾上腺皮质类固醇，环糊精，多糖和载体如水，其通过使用均质混合器将环糊精中的肾上腺皮质类固醇包合在环糊精中 以形成包合物，并且在均匀搅拌的同时将包合物加入到多糖的水溶液中，以将包合物溶解在水溶液中，以及在哺乳动物受试者中治疗皮炎的方法，其包括对所述 服用有效量的上述皮炎外用治疗组合物。 根据本发明的用于皮炎的外用治疗组合物是非常安全的，可以治疗诸如特应性皮炎等的皮炎而没有副作用。

公开(公告)号：US5505847A

公开(公告)日：1996-04-09

申请号：US337744

申请日：1994-11-14

申请人： Hajime Yamada ,  Akira Yamada

发明人： Hajime Yamada ,  Akira Yamada

IPC分类号： A47K3/00 ,  A61H33/00 ,  A61H33/04 ,  B01D35/027 ,  C02F1/46

CPC分类号： A61H33/04 ,  A61H2033/0037 ,  A61H2033/048

摘要： The present invention is a bath which circulates and recycles a multiple mineral solution. The solution is released from the bathtub, filtered at the hair collector and the filtration device, sterilized at the electrolytic sterilizer, and returned to the tub. Non-metallic pipe is used along the circulation route. The electrolytic sterilizer employs several electrode panels which are placed perpendicular to the direction of flow of the solution. The filtration device features a rubber lining in the portions which come into contact with the solution, and has inside of it a dish onto which is lain filter sand. With the use of this invention, it becomes possible to repeatedly use and reuse a highly viscous solution containing multiple minerals as the recycling fluid, jams become infrequent, the filtration and reverse cleansing procedures become less time consuming, and the solution can be effectively sterilized.

摘要翻译： 本发明是一种使多种矿物质溶液循环和循环的浴。 溶液从浴缸中释放，在收集器和过滤装置处过滤，在电解消毒器处灭菌，并返回到桶中。 沿循环路线使用非金属管。 电解消毒器采用几个垂直于溶液流动方向放置的电极板。 过滤装置在与溶液接触的部分中具有橡胶衬里，并且在其内部具有用于过滤砂的盘。 通过使用本发明，可以重复使用和再利用含有多种矿物质的高粘度溶液作为再循环液，堵塞变得不频繁，过滤和反向清洗程序变得更加耗时，并且可以有效地消毒溶液。

公开(公告)号：US20210128437A1

公开(公告)日：2021-05-06

申请号：US16493482

申请日：2018-03-28

申请人： CAC CORPORATION

发明人： Kiyoko YAMADA ,  Kenji MATSUSHITA

IPC分类号： A61K8/60 ,  A61K31/7004 ,  A61Q17/00 ,  A61K8/04

摘要： An agent for enhancing the skin barrier that can enhance skin barrier functions is provided. The agent for enhancing the skin barrier, including at least one of a monosaccharide and a sugar alcohol, in which a pH is 4.0 to 7.0 is provided.

公开(公告)号：US20050203900A1

公开(公告)日：2005-09-15

申请号：US11074322

申请日：2005-03-07

申请人： Takahiro Nakamura ,  Yoichi Inagaki

发明人： Takahiro Nakamura ,  Yoichi Inagaki

IPC分类号： G06F17/30

CPC分类号： G06F16/334

摘要： A method and system for retrieving information from a set of documents using one retrieval keyword or more is capable of remarkably increasing the relevance ratio of a retrieval result. The system includes a category dictionary for storing category information containing morphemes included in the documents in a hierarchical structure, a morpheme-ID array produced by converting the set of documents into a set of fixed-length IDs in accordance with the morphemes while maintaining order information of the morphemes, and a retrieval part for retrieving a morpheme ID from the morpheme-ID array. The retrieval part retrieves a morpheme ID of the retrieval word and of any morpheme co-occurring with the retrieval word and having category information which matches retrieval-category information.

摘要翻译： 使用一个检索关键字或更多的检索关键词从一组文档中检索信息的方法和系统能够显着增加检索结果的相关性比例。 该系统包括用于存储包含在分层结构中的文档中的词素的类别信息的类别字典，通过根据语素将文档集合转换成一组固定长度的ID而产生的语素ID阵列，同时保持订单信息 的语素，以及用于从语素ID数组中检索语素ID的检索部分。 检索部分检索检索词和与检索词共同发生的任何语素的语素ID，并具有与检索类别信息相匹配的类别信息。