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    METHOD FOR MODIFYING RNA BINDING PROTIEN USING PPR MOTIF
    2.
    发明申请
    METHOD FOR MODIFYING RNA BINDING PROTIEN USING PPR MOTIF 审中-公开

    公开(公告)号：US20170260242A1

    公开(公告)日：2017-09-14

    申请号：US15326176

    申请日：2011-03-11

    申请人： Takahiro Nakamura ,  Keiko Kobayashi

    发明人： Takahiro Nakamura ,  Keiko Kobayashi

    IPC分类号： C07K14/415

    CPC分类号： C07K14/415

    摘要： The objects of the present invention are to identify the amino acids that play a principal role for the PPR motif to act as a RNA binding unit, as well as to provide a technology that regulates the RNA binding property thereof. The present invention provides a method for altering the RNA binding property of a PPR protein having one or more, preferably 2 or more, and more preferably 2-14 PPR motifs that consist of a polypeptide with a length of 30-38 amino acids, comprising a step of substituting one or more of the 1st, 4th, 8th, 9th, and 12th amino acids in the one or more PPR motifs with a different amino acid.

    Process for production of modified conjugated diene rubber, modified conjugated diene rubber, and rubber composition
    4.
    发明授权
    Process for production of modified conjugated diene rubber, modified conjugated diene rubber, and rubber composition 有权
    改性共轭二烯橡胶，改性共轭二烯橡胶，橡胶组合物的制造方法

    公开(公告)号：US09550840B2

    公开(公告)日：2017-01-24

    申请号：US13638767

    申请日：2011-03-30

    申请人： Takahiro Nakamura ,  Ryouji Tanaka

    发明人： Takahiro Nakamura ,  Ryouji Tanaka

    IPC分类号： C08C19/44 ,  B60C1/00 ,  C08K3/04 ,  C08K3/36 ,  C08L15/00 ,  C08K5/544

    CPC分类号： C08C19/44 ,  B60C1/00 ,  C08K3/04 ,  C08K3/36 ,  C08K5/544 ,  C08L15/00

    摘要： To provide a producing method of conjugated diene rubber which can be used as a starting material of cross-linked rubber which is used for such as tire tread and can enhance low fuel consumption performance.The method of producing modified conjugated diene rubber, comprising: a process step (a) wherein a conjugated diene polymer with an alkali metal or alkaline-earth metal active terminal, which polymer is obtained from polymerization of a conjugated diene compound or polymerization of a conjugated diene compound with an aromatic vinyl compound, is allowed to react with a hydrocarbyloxysilane compound having in its molecule at least one or more of each of the following functional groups (I): a hydrocarbyloxysilyl group and (II): a nitrogen-containing group formed by substituting one protective group for one hydrogen atom of a secondary amine, a tertiary amino group, an imino group, a pyridyl group to obtain a modified conjugated diene polymer with the functional group (II), and a process step (b) wherein the modified conjugated diene polymer produced in the process step (a) is mixed with an onium-forming agent.

    摘要翻译： 制备改性共轭二烯橡胶的方法包括：其中具有碱金属或碱土金属活性末端的共轭二烯聚合物的该方法步骤（a），该共聚物由共轭二烯化合物的聚合或共轭二烯化合物的聚合获得， 使具有芳族乙烯基化合物的二烯化合物与其分子中具有以下官能团（I）中的至少一种以上的烃氧基硅烷化合物反应：烃氧基甲硅烷基和（II）：形成的含氮基团 通过用一个保护基团取代仲胺，叔氨基，亚氨基，吡啶基的一个氢原子，得到具有官能团（II）的改性共轭二烯聚合物，以及工艺步骤（b），其中 在工艺步骤（a）中制备的改性共轭二烯聚合物与成鎓剂混合。

    TIME-DOMAIN SPECTROSCOPY AND TIME-DOMAIN SPECTROSCOPIC ANALYSIS SYSTEM
    6.
    发明申请
    TIME-DOMAIN SPECTROSCOPY AND TIME-DOMAIN SPECTROSCOPIC ANALYSIS SYSTEM 有权
    时域光谱和时域光谱分析系统

    公开(公告)号：US20150028211A1

    公开(公告)日：2015-01-29

    申请号：US14382802

    申请日：2012-03-30

    申请人： Takahiro Nakamura ,  Nobuhiro Shiramizu

    发明人： Takahiro Nakamura ,  Nobuhiro Shiramizu

    IPC分类号： G01N21/35

    CPC分类号： G01N21/3586 ,  G01N2201/06113

    摘要： The time-domain spectroscopy analysis system includes a splitter for splitting pulsed light entered, a variable delayer for delaying timing of a first part of the pulsed light split by the splitter, an electromagnetic wave generator for converting a second part of the pulsed light split by the splitter into an electromagnetic wave, a detector for detecting measurement data from a pulse having passed through a measurement object subjected to the electromagnetic wave emitted from the electromagnetic wave generator, and the pulse outputted from the variable delayer, and a comparator for detecting a phase difference between the pulsed light before being entered into the electromagnetic wave generator and the pulsed light outputted from the variable delayer, wherein a result obtained by the comparator is fed back to the variable delayer.

    摘要翻译： 时域光谱分析系统包括用于分离入射的脉冲光的分光器，用于延迟由分光器分离的脉冲光的第一部分的定时的可变延迟器，电磁波发生器，用于将分裂的脉冲光的第二部分转换成 分离器成为电磁波，检测器，用于检测来自经受从电磁波发生器发射的电磁波的测量对象的脉冲的测量数据和从可变延迟器输出的脉冲;以及比较器，用于检测相位 在进入电磁波发生器之前的脉冲光与从可变延迟器输出的脉冲光之间的差异，其中由比较器获得的结果被反馈给可变延迟器。

    Semiconductor device
    7.
    发明授权
    Semiconductor device 有权
    半导体器件

    公开(公告)号：US08917522B2

    公开(公告)日：2014-12-23

    申请号：US13576225

    申请日：2011-01-20

    申请人： Takahiro Nakamura ,  Haruei Kokuho ,  Takahiro Yamada ,  Koichi Kimura

    发明人： Takahiro Nakamura ,  Haruei Kokuho ,  Takahiro Yamada ,  Koichi Kimura

    IPC分类号： H01L25/16 ,  H01L23/528 ,  H05K1/02 ,  H01L25/18

    CPC分类号： H01L25/162 ,  H01L23/5286 ,  H01L25/18 ,  H01L2924/0002 ,  H05K1/0216 ,  H05K1/0227 ,  H05K1/0262 ,  H05K2201/10166 ,  H01L2924/00

    摘要： A semiconductor device that can suppress variation of GND potential of a control board and prevent malfunction of IC without restricting a mounting direction of the IC of the control board is provided. In a power module 10 as a semiconductor device in which an insulating board 31 having a power switching element 24 and a control board 22 having IC 50 for controlling the power switching element 24 are vertically provided in a case body 19, GND pins 61 are provided at both the sides of the IC 50, a GND pattern 51 to which the GND pins 61 of the IC 50 are connected is provided in the control board 22, and a GND loop breaking slit 70 as a breaking portion for breaking a GND loop formed by electrical connection of the IC 50, the GND pins 61 at both the sides of the IC 50 and the GND pattern 51 is provided to the GND pattern 51.

    摘要翻译： 提供一种可以抑制控制板的GND电位的变化并防止IC的故障而不限制控制板的IC的安装方向的半导体器件。 在作为半导体装置的功率模块10中，具有功率开关元件24的绝缘板31和具有用于控制功率开关元件24的IC 50的控制板22垂直设置在壳体主体19中，设置有GND引脚61 在IC 50的两侧，在控制板22上设置有连接有IC 50的GND引脚61的GND图形51，作为断开形成的GND环的断路部的GND环断路缝隙70 通过IC 50的电连接，将IC 50的两侧的GND引脚61和GND图案51提供给GND图案51。

    Housing member for use in disk drive apparatus, motor unit, disk drive apparatus, and method of manufacturing housing member
    9.
    发明授权
    Housing member for use in disk drive apparatus, motor unit, disk drive apparatus, and method of manufacturing housing member 有权
    用于磁盘驱动装置的壳体构件，电机单元，磁盘驱动装置以及制造壳体构件的方法

    公开(公告)号：US08358485B2

    公开(公告)日：2013-01-22

    申请号：US13423328

    申请日：2012-03-19

    申请人： Kiyofumi Inoue ,  Shozo Tagata ,  Takahiro Nakamura ,  Koji Baba ,  Toshikazu Himeno

    发明人： Kiyofumi Inoue ,  Shozo Tagata ,  Takahiro Nakamura ,  Koji Baba ,  Toshikazu Himeno

    IPC分类号： G11B17/02

    CPC分类号： G11B25/043 ,  Y10T29/49025

    摘要： A housing member for use in a disk drive apparatus includes a rectangular bottom portion and a side wall portion arranged to extend upward from an outer circumferential portion of the bottom portion. The side wall portion includes four outside surfaces including a first outside surface and a second outside surface perpendicular or substantially perpendicular to the first outside surface. The first outside surface includes a first cutting base region. The second outside surface includes a second cutting base region. The bottom portion includes a bearing fixing portion arranged to fix a bearing mechanism of a motor arranged to rotate a disk.

    摘要翻译： 用于盘驱动装置的壳体构件包括矩形底部和布置成从底部的外周部向上延伸的侧壁部。 侧壁部分包括四个外表面，其包括垂直于或基本垂直于第一外表面的第一外表面和第二外表面。 第一外表面包括第一切割基底区域。 第二外表面包括第二切割基底区域。 底部包括轴承固定部分，其布置成固定设置成使盘旋转的马达的轴承机构。

    EYE DROPS
    10.
    发明申请
    EYE DROPS 有权
    眼药水

    公开(公告)号：US20120165273A1

    公开(公告)日：2012-06-28

    申请号：US13394194

    申请日：2010-09-24

    申请人： Takahiro Nakamura ,  Yuichiro Nakada ,  Takashi Nagano ,  Masatsugu Nakamura

    发明人： Takahiro Nakamura ,  Yuichiro Nakada ,  Takashi Nagano ,  Masatsugu Nakamura

    IPC分类号： A61K38/07 ,  A61P27/02

    CPC分类号： A61K38/07 ,  A61K9/0048 ,  C07K5/1013 ,  C07K5/1016 ,  A61K2300/00

    摘要： An eyedrop containing a peptide having an amino acid sequence represented by Ser-Ser-Ser-Arg (“SSSR”), or a pharmacologically acceptable salt thereof; and a peptide having an amino acid sequence represented by Phe-Gly-Leu-Met-NH2 (“FGLM”), or a pharmacologically acceptable salt thereof. The concentration ratio between SSSR or a pharmacologically acceptable salt thereof and FGLM or a pharmacologically acceptable salt thereof is between 1/15 and 1/50. The concentration of SSSR or a pharmacologically acceptable salt thereof is between 0.001% and 0.3% (w/v) and the concentration of FGLM or a pharmacologically acceptable salt thereof is between 0.015% and 1.5% (w/V). The pH of the eye drop is maintained between 2.5 and 6.5.

    摘要翻译： 含有具有由Ser-Ser-Ser-Arg（“SSSR”）表示的氨基酸序列的肽或其药理学上可接受的盐的滴眼剂; 和具有由Phe-Gly-Leu-Met-NH 2（“FGLM”）表示的氨基酸序列的肽或其药理学上可接受的盐。 SSSR或其药理学上可接受的盐与FGLM或其药理学上可接受的盐之间的浓度比为1/15至1/50。 SSSR或其药理学上可接受的盐的浓度为0.001％至0.3％（w / v），并且FGLM或其药理学上可接受的盐的浓度为0.015％至1.5％（w / V）。 滴眼液的pH值保持在2.5至6.5之间。