公开(公告)号：US07157529B2

公开(公告)日：2007-01-02

申请号：US10862724

申请日：2004-06-07

申请人： William H. Campbell ,  Yung K. Kim ,  Charles E. Skinner

发明人： William H. Campbell ,  Yung K. Kim ,  Charles E. Skinner

IPC分类号： C08F283/12

CPC分类号： C08G83/003 ,  B01J20/3204 ,  B01J20/3219 ,  B01J20/3257 ,  B01J20/3272 ,  B01J20/328 ,  B01J20/3289 ,  C07K1/22 ,  C08L101/005 ,  Y10T428/2991 ,  Y10T428/2995 ,  Y10T428/2998

摘要： Multi-layered macromolecules wherein the layers are covalently bonded together and wherein the macromolecules are covalently bonded to solid particulate substrates, methods for the preparation of such compositions, and methods for their uses in a multitude of end use applications ranging from the purification of waste chemical and metal process streams to the separation and identification of proteins, peptides, and oligionucleotides.

公开(公告)号：US08323502B2

公开(公告)日：2012-12-04

申请号：US13374574

申请日：2011-12-31

申请人： Charles E. Skinner ,  William Henry Campbell ,  Yung K. Kim

发明人： Charles E. Skinner ,  William Henry Campbell ,  Yung K. Kim

IPC分类号： B01D15/08

CPC分类号： C08G83/003 ,  B01J20/3204 ,  B01J20/3219 ,  B01J20/3257 ,  B01J20/3272 ,  B01J20/328 ,  B01J20/3289 ,  C07K1/22 ,  C08L101/005 ,  Y10T428/2991 ,  Y10T428/2995 ,  Y10T428/2998

摘要： Multi-layered macromolecules wherein the layers are covalently bonded together and wherein the macromolecules are covalently bonded to solid particulate substrates, methods for the preparation of such compositions, and methods for their uses in a multitude of end use applications ranging from the purification of waste chemical and metal process streams to the separation and identification of proteins, peptides, and oligionucleotides.

公开(公告)号：US20040224157A1

公开(公告)日：2004-11-11

申请号：US10862724

申请日：2004-06-07

申请人： Diazem Corporation

发明人： William Henry Campbell ,  Yung K. Kim ,  Charles E. Skinner

IPC分类号： C08L031/00

CPC分类号： C08G83/003 ,  B01J20/3204 ,  B01J20/3219 ,  B01J20/3257 ,  B01J20/3272 ,  B01J20/328 ,  B01J20/3289 ,  C07K1/22 ,  C08L101/005 ,  Y10T428/2991 ,  Y10T428/2995 ,  Y10T428/2998

摘要： Multi-layered macromolecules wherein the layers are covalently bonded together and wherein the macromolecules are covalently bonded to solid particulate substrates, methods for the preparation of such compositions, and methods for their uses in a multitude of end use applications ranging from the purification of waste chemical and metal process streams to the separation and identification of proteins, peptides, and oligionucleotides.

公开(公告)号：US08114294B2

公开(公告)日：2012-02-14

申请号：US12151150

申请日：2008-05-02

申请人： Charles E. Skinner ,  William Henry Campbell ,  Yung K. Kim

发明人： Charles E. Skinner ,  William Henry Campbell ,  Yung K. Kim

IPC分类号： B01D15/08

CPC分类号： C08G83/003 ,  B01J20/3204 ,  B01J20/3219 ,  B01J20/3257 ,  B01J20/3272 ,  B01J20/328 ,  B01J20/3289 ,  C07K1/22 ,  C08L101/005 ,  Y10T428/2991 ,  Y10T428/2995 ,  Y10T428/2998

摘要： Multi-layered macromolecules wherein the layers are covalently bonded together and wherein the macromolecules are covalently bonded to solid particulate substrates, methods for the preparation of such compositions, and methods for their uses in a multitude of end use applications ranging from the purification of waste chemical and metal process streams to the separation and identification of proteins, peptides, and oligionucleotides.

摘要翻译： 多层大分子，其中这些层共价键合在一起，并且其中大分子共价键合到固体颗粒基质上，制备这种组合物的方法，以及用于多种终端应用的方法，从废化学品的纯化 和金属工艺流分离和鉴定蛋白质，肽和寡聚核苷酸。

公开(公告)号：US20070077431A1

公开(公告)日：2007-04-05

申请号：US11598360

申请日：2006-11-13

申请人： Charles Skinner ,  William Campbell ,  Yung Kim

发明人： Charles Skinner ,  William Campbell ,  Yung Kim

IPC分类号： B32B1/00

CPC分类号： C08G83/003 ,  B01J20/3204 ,  B01J20/3219 ,  B01J20/3257 ,  B01J20/3272 ,  B01J20/328 ,  B01J20/3289 ,  C07K1/22 ,  C08L101/005 ,  Y10T428/2991 ,  Y10T428/2995 ,  Y10T428/2998

摘要： Multi-layered macromolecules wherein the layers are covalently bonded together and wherein the macromolecules are covalently bonded to solid particulate substrates, methods for the preparation of such compositions, and methods for their uses in a multitude of end use applications ranging from the purification of waste chemical and metal process streams to the separation and identification of proteins, peptides, and oligionucleotides.

摘要翻译： 多层大分子，其中这些层共价键合在一起，并且其中大分子共价键合到固体颗粒基质上，制备这种组合物的方法，以及用于多种终端应用的方法，从废化学品的纯化 和金属工艺流分离和鉴定蛋白质，肽和寡聚核苷酸。

公开(公告)号：US20060237365A1

公开(公告)日：2006-10-26

申请号：US11475316

申请日：2006-06-27

申请人： Yung Kim ,  David Karpovich ,  William Campbell ,  Ling Yang

发明人： Yung Kim ,  David Karpovich ,  William Campbell ,  Ling Yang

IPC分类号： C02F1/42

CPC分类号： C08G83/005 ,  A61K8/84 ,  A61Q19/00 ,  B01J20/26 ,  B01J20/28033 ,  B01J20/285 ,  B01J20/286 ,  B01J20/3242 ,  B01J20/3265 ,  B01J20/3268 ,  B01J20/328 ,  B01J45/00 ,  C08G83/002 ,  C09D201/005

摘要： The present invention provides a silicone derivatized macromolecule that is supported on a particulate support or a separation membrane and method for making that composition. The silicon-derivatized macromolecule can also be combined with chiral ligands or chelated metals. The applications for the silicone derivatized macromolecule variety including use in HPLC separations, in purification process and in personal care formulations.

公开(公告)号：US5922449A

公开(公告)日：1999-07-13

申请号：US964663

申请日：1997-11-05

申请人： Anthony Revis

发明人： Anthony Revis

IPC分类号： B01D15/08 ,  B01J20/286 ,  B01J20/32 ,  B01J20/22

CPC分类号： B01J20/286 ,  B01J20/06 ,  B01J20/08 ,  B01J20/103 ,  B01J20/28019 ,  B01J20/28057 ,  B01J20/28078 ,  B01J20/28083 ,  B01J20/3092 ,  B01J20/3204 ,  B01J20/3217 ,  B01J20/3227 ,  B01J20/3246 ,  B01J20/3257 ,  B01J20/3259 ,  B01J20/3261 ,  B01J20/3263 ,  B01J20/3285 ,  B01J2220/54 ,  B01J2220/58 ,  Y10T428/249955 ,  Y10T428/249956 ,  Y10T428/2995 ,  Y10T428/31663

摘要： A bonded phase material useful with a chromatographic separation process. The bonded phase material includes a hydroxyl bearing porous material, a first controlled stoichiometric amount of a first interactive silane covalently bonded to the surface of the hydroxyl bearing porous material and at least one additional interactive silane covalently bonded to the surface of the hydroxyl bearing porous material to provide the porous material with a gradient of functionality of varied polarity creates a unique overall polarity which is not obtainable by the separate interactive silanes themselves. The method of silating the porous material includes sequential application of controlled stoichiometric amounts of the interactive silanes.

摘要翻译： 用于色谱分离过程的键合相材料。 键合相材料包括含羟基的多孔材料，第一受控化学计量量的共价键合到含羟基的多孔材料的表面上的第一相互作用的硅烷和至少一种共价结合到含羟基的多孔材料的表面的另外的相互作用的硅氧烷 为了提供具有不同极性的功能梯度的多孔材料产生独特的总体极性，其不能由单独的交互硅烷本身获得。 硅化多孔材料的方法包括顺序施加受控化学计量的相互作用的硅烷。