公开(公告)号：US10077336B2

公开(公告)日：2018-09-18

申请号：US13516426

申请日：2010-12-15

申请人： Maxim Peretolchin ,  Marta Reinoso Garcia ,  Holger Tuerk ,  Daniel Schoenfelder ,  Sophia Ebert

发明人： Maxim Peretolchin ,  Marta Reinoso Garcia ,  Holger Tuerk ,  Daniel Schoenfelder ,  Sophia Ebert

IPC分类号： C08G73/06 ,  C08G83/00 ,  C08G73/02 ,  C08G71/02 ,  C08G73/00 ,  C07D251/70 ,  C11D1/90 ,  C11D1/92 ,  C11D3/28 ,  C08L79/02 ,  C08L79/04 ,  C04B24/16 ,  C04B24/24 ,  C04B24/32 ,  C04B103/40

CPC分类号： C08G73/0273 ,  C04B24/166 ,  C04B24/243 ,  C04B24/32 ,  C04B2103/408 ,  C08G73/0644 ,  C08G83/005 ,  C08G83/006 ,  C08L79/02 ,  C08L79/04 ,  C11D1/90 ,  C11D1/92 ,  C11D3/28

摘要： The present invention relates to a method for producing amphiphilic functionalized highly branched melamine-polyamine polymers by condensing melamine and optionally a melamine derivate having at least one different amine having at least two primary amino groups and optionally also with urea and/or at least one urea derivative and/or with at least one at least difunctional diisocyanate or polyisocyanate and/or at least one carbolic acid having at least two carboxyl groups or at least one derivative thereof, optionally quaternizing a portion of the amino groups of the polymer thereby obtained, reacting the polymer thus obtained with at least one compound capable of undergoing a condensation or addition reaction with amino groups, and optionally quaternizing at least part of the amino groups of the polymer obtained in the first step. The invention further relates to the amphiphilic functionalized highly branched melamine-polyamine polymers that can be obtained by the method according to the invention, and to the use thereof as surface active agents.

公开(公告)号：US09714319B2

公开(公告)日：2017-07-25

申请号：US14615009

申请日：2015-02-05

申请人： Stratasys, Inc.

发明人： Jeffrey J. Cernohous ,  Garrett S. Van Gorden

IPC分类号： C04B28/04 ,  C08G63/60 ,  C08G63/08 ,  C08K5/00 ,  C08K5/10 ,  C08K5/14 ,  C08K5/3492 ,  C08L101/00 ,  C08L101/16 ,  C08G83/00 ,  C08K5/52 ,  C08K5/49

CPC分类号： C08G63/08 ,  C08G83/005 ,  C08G2261/132 ,  C08K5/0033 ,  C08K5/0066 ,  C08K5/10 ,  C08K5/14 ,  C08K5/34928 ,  C08K5/49 ,  C08K5/5205 ,  C08L101/005 ,  C08L101/16

摘要： Hyper-branched biodegradable polymers are produced by melt processing biodegradable polymers with a branching agent at temperatures that promote free radical reactions between the biodegradable polymer and the branching agent. The biodegradable compositions have an excellent balance of mechanical properties and are suitable for flame retardant applications.

公开(公告)号：US20170145127A1

公开(公告)日：2017-05-25

申请号：US15426863

申请日：2017-02-07

申请人： BRASKEM AMERICA, INC.

发明人： Jonas Alves FERNANDES

IPC分类号： C08F126/02 ,  C08F110/06

CPC分类号： C08F8/30 ,  C08F110/06 ,  C08F126/02 ,  C08G81/021 ,  C08G83/005 ,  C08F2500/08

摘要： This invention relates to a process for forming a long-chain branched polymer and a long-chain branched polymer resulting from the process. The process comprises reacting (a) a polyolefin base polymer with (b) a coupling agent comprising a polymeric coupling agent, optionally blended with a molecular coupling agent, the polymeric coupling agent being a modified polyolefin having a reactive coupling group at one or more terminal ends of the modified polyolefin chain, to couple the polyolefin base polymer (a) with the coupling agent (b) to form a long-chain branched polymer having a long-chain branching and/or higher surface energy relative to the polyolefin base polymer.

公开(公告)号：US09475894B2

公开(公告)日：2016-10-25

申请号：US14314756

申请日：2014-06-25

申请人： CHINA PETROLEUM & CHEMICAL CORPORATION ,  SINOPEC ZHONGYUAN OILFIELD SERVICE CORPORATION DRILLING ENGINEERING RESEARCH INSTITUTE

发明人： Zhonghua Wang

IPC分类号： C08F22/38 ,  C08F220/58 ,  C08F220/60 ,  C08F222/06

CPC分类号： C08G83/005 ,  C07C237/10 ,  C08F22/38 ,  C08F220/58 ,  C08F220/60 ,  C08F222/06 ,  C08F222/38 ,  C09K8/035 ,  C09K8/12

摘要： A dendritic polymer, a dendritic polymer monomer, and a hyperbranched copolymer are described. The dendritic polymer monomer has a structure denoted by Z′-(Q)n-Y, wherein Z′ represents a structure denoted by the following formula (a) and/or formula (b), Q represents a dendritic constitutional repeating unit of the dendritic polymer monomer, n represents the generation number of the dendritic polymer monomer, and is an integer within a range of 2-6, Y represents a group that contains SO3− or COO−, R14-R16 can be identical to or different from each other, and are H or C1-C5 alkyl respectively. The monomer can be used as a copolymerizable monomer for preparing a hyperbranched polymer applicable to oil fields, the obtained hyperbranched polymer can be used as an inhibiting filtrate reducer for drilling fluid, flocculating agent, encapsulating agent, heat-resistant and salinity-resistant polymer flooding agent, and thickening agent for fracturing liquid, etc.

摘要翻译： 描述了树枝状聚合物，树枝状聚合物单体和超支化共聚物。 树枝状聚合物单体具有由Z' - （Q）n Y表示的结构，其中Z'表示由下式（a）和/或式（b）表示的结构，Q表示树枝状聚合物的树枝状结构重复单元 单体，n表示树枝状聚合物单体的产生数，为2-6的整数，Y表示含有SO 3 - 或COO-的基团，R 14 -R 16可以相同或不同， 分别为H或C 1 -C 5烷基。 该单体可以用作制备适用于油田的超支化聚合物的可共聚单体，所获得的超支化聚合物可用作钻井液，絮凝剂，包封剂，耐热和耐盐性聚合物驱油的抑制滤液还原剂 粉剂，增稠剂等。

公开(公告)号：US09453113B2

公开(公告)日：2016-09-27

申请号：US14330360

申请日：2014-07-14

申请人： SINVENT AS

发明人： Ferdinand Männle ,  Christian Simon ,  Jest Beylich ,  Keith Redford ,  Britt Sommer ,  Einar Hinrichsen ,  Erik Andressen ,  Kjell Olafsen ,  Terje Didriksen

IPC分类号： C08G77/26 ,  C08G83/00 ,  C08G77/388 ,  C08G77/54 ,  C07F7/10

CPC分类号： C08G83/005 ,  C07F7/10 ,  C08G77/388 ,  C08G77/54

摘要： Polybranched organic/inorganic hybrid polymer and method for its manufacture. The hybrid polymer has the form of an inorganic core carrying organic branches. The core is first prepared by controlled hydrolysis and condensation of a silane with a structure: X—B—Si(—Y)3 in which X=NR1R2, while R1, R2 are chosen among hydrogen, alkyl and aryl, or R1, R2 are chosen among condensation products, addition products of one or more type of chemical substances such as acids, alcohols, phenols, amines, aldehydes or epoxides. B is a linkage group chosen among alkylene and arylene which may include oxygen, nitrogen, sulphur, phosphorous, silicon and boron. Y is chosen among hydrolyzable residues such as alkoxy, carboxyl, and halogen. The organic branches are developed by substituting N—H hydrogen atoms in the X—B group by reactions that are typical for primary and secondary amines, and/or by adding an acid that causes an addition to the N atoms of the X—B group in the core. Specific uses of the hybrid polymers are also indicated.

摘要翻译： 多分支有机/无机杂化聚合物及其制造方法。 杂化聚合物具有携带有机分支的无机核的形式。 首先通过控制水解和缩合具有X = NR1R2的结构的X-B-Si（-Y）3制备核心，而R1，R2选自氢，烷基和芳基，或R1，R2 选自缩合产物，一种或多种类型的化学物质如酸，醇，酚，胺，醛或环氧化物的加成产物。 B是选自亚烷基和亚芳基中的连接基团，其可以包括氧，氮，硫，磷，硅和硼。 Y选自可水解残基如烷氧基，羧基和卤素。 通过用于伯胺和仲胺典型的反应和/或通过加入引入X-B基团的N原子的酸来代替X-B基团中的N-H氢原子而开发有机分支 在核心。 还指出了混合聚合物的具体用途。

公开(公告)号：US09295734B2

公开(公告)日：2016-03-29

申请号：US14126803

申请日：2012-06-22

申请人： Eiichi Ozeki ,  Shunsaku Kimura ,  Akira Makino

发明人： Eiichi Ozeki ,  Shunsaku Kimura ,  Akira Makino

IPC分类号： A61K8/00 ,  A61K49/00 ,  A61K9/107 ,  B82Y40/00 ,  A61K47/34 ,  A61K9/51 ,  C08L101/00 ,  A61K49/12 ,  A61K47/48 ,  C08G83/00

CPC分类号： A61K49/0054 ,  A61K9/1075 ,  A61K9/5153 ,  A61K47/34 ,  A61K47/641 ,  A61K49/0002 ,  A61K49/0034 ,  A61K49/0082 ,  A61K49/124 ,  B82Y40/00 ,  C08G69/44 ,  C08G83/005 ,  C08G83/008 ,  C08L101/005 ,  Y10S424/16 ,  Y10T428/2982

摘要： Provided is a polymeric micelle pharmaceutical preparation that can increase the ratio of contrast at tumor site to background contrast in a short period of time after administration of a lactosome and can suppress the ABC phenomenon so that the lactosome can be administered more than once within a short span. A branched-type amphiphilic block polymer comprising: a multi-branched hydrophilic block comprising sarcosine; and a hydrophobic block comprising polylactic acid. The branched-type amphiphilic block polymer, wherein the number of branches of the hydrophilic block is 3. A molecular assembly comprising the branched-type amphiphilic block polymer. The molecular assembly further comprising a linear type amphiphilic block polymer.

摘要翻译： 提供了一种聚合物胶束药物制剂，其可以在施用乳糖体后在短时间内增加肿瘤部位的对比度与背景对比度的比例，并且可以抑制ABC现象，使得在短时间内可以多次施用 跨度。 一种支链型两亲嵌段聚合物，其包含：包含肌氨酸的多支链亲水嵌段; 和包含聚乳酸的疏水嵌段。 支链型两亲性嵌段聚合物，其中亲水嵌段的分支数为3.包含支链型两亲性嵌段聚合物的分子组合物。 分子组合还包含线性型两亲嵌段聚合物。

公开(公告)号：US20160039848A1

公开(公告)日：2016-02-11

申请号：US14773942

申请日：2014-01-31

申请人： SHIN-ETSU CHEMICAL CO., LTD.

发明人： Hatsuhiko HATTORI

IPC分类号： C07F7/08

CPC分类号： C07F7/0838 ,  C07C271/16 ,  C08F290/068 ,  C08G77/08 ,  C08G77/38 ,  C08G77/46 ,  C08G83/005

摘要： A symmetric hyperbranched type silicone-modified polymerizable compound contains a compound represented by the following general formula (1). A hyperbranched type silicone-modified polymerizable compound has flexibility at the branched skeleton itself than the conventional ones, and reactivity of a polymerizable functional group is good and it is positionally and sterically symmetric, while it has a highly branched structure having siloxane chains. [(RARB)2CHOCH2]2CHORCcRD  (1) RA represents a monovalent linear, branched or cyclic siloxane chain; RB represents a divalent hydrocarbonylene methylene ether group represented by —CH2CRb1Rb2(CRb3Rb4)n1OCH2—, each of Rb1, Rb2, Rb3 and Rb4 may be the same or different from each other and represents a hydrogen atom or a linear, branched or cyclic hydrocarbon group having 1 to 10 carbon atoms which may be bonded to each other, “n1” represents an integer selected from 0 to 10; RC, a divalent linking group; “c”, 0 or 1; and RD, an unsaturated polymerizable functional group.

摘要翻译： 对称的超支化型硅氧烷改性聚合性化合物含有下述通式（1）表示的化合物。 超支化型有机硅改性聚合性化合物在分支骨架本身具有比现有的柔软性，并且聚合性官能团的反应性良好且位置和空间对称，而具有高分支性的具有硅氧烷链的结构。 [（RARB）2CHOCH2] 2CHORCcRD（1）RA表示一价直链，支链或环状的硅氧烷链; RB表示由-CH 2 CRbR 1 R b2（CRb 3 R b 4）n 1 OCH 2 - 表示的二价亚烷基亚甲基醚基，Rb1，Rb2，Rb3和Rb4各自可以相同或不同，表示氢原子或直链，支链或环状烃基 可以相互结合的碳原子数1〜10，n1表示0〜10的整数， RC，二价连接基团; “c”，0或1; RD为不饱和聚合性官能团。

公开(公告)号：US20150361238A1

公开(公告)日：2015-12-17

申请号：US14646185

申请日：2013-11-21

申请人： YAMAGATA UNIVERSITY ,  NISSAN CHEMICAL INDUSTRIES, LTD.

发明人： Masataka SUGIMOTO ,  Motonobu MATSUYAMA

IPC分类号： C08J9/00

CPC分类号： C08J9/0061 ,  C08F220/24 ,  C08F222/1006 ,  C08G83/005 ,  C08J9/122 ,  C08J2201/032 ,  C08J2203/06 ,  C08J2203/08 ,  C08J2205/044 ,  C08J2205/046 ,  C08J2325/06 ,  C08J2325/12 ,  C08J2333/12 ,  C08J2333/16 ,  C08J2333/20 ,  C08J2400/202 ,  C08L25/06 ,  C08L33/12 ,  C08L33/16 ,  C08F2222/1013 ,  C08F212/36 ,  C08L33/14

摘要： A thermoplastic resin foam that is formed of a thermoplastic resin composition including 100 parts by mass of a thermoplastic resin and 0.001 to 30 parts by mass of a fluorine-containing highly branched polymer, wherein the fluorine-containing highly branched polymer is a fluorine-containing highly branched polymer that is obtained by polymerizing a monomer A having in a molecule two or more radical-polymerizable double bonds with a monomer B having in a molecule a fluoroalkyl group and at least one radical-polymerizable double bond, in presence of a polymerization initiator C in an amount of 5 to 200 mol % with respect to the number of moles of the monomer A; and a method for producing the foam.

摘要翻译： 由热塑性树脂100质量份和含氟高支链状聚合物0.001〜30质量份的热塑性树脂组合物形成的热塑性树脂发泡体，其中，含氟高支链状聚合物为含氟 在聚合引发剂的存在下，通过使分子内具有分子中具有2个以上自由基聚合性双键的单体A与分子内具有氟烷基和至少一个自由基聚合性双键的单体B聚合而得到的高支化聚合物 相对于单体A的摩尔数为5〜200摩尔％的C; 和泡沫体的制造方法。

公开(公告)号：US09186410B2

公开(公告)日：2015-11-17

申请号：US13581463

申请日：2011-03-01

申请人： Helen Burt ,  Donald Brooks ,  Jayachandran Kizhakkedathu ,  Richard Liggins ,  Dechi Guan ,  Lu Ye ,  Clement Mugabe ,  Alan So ,  Martin E. Gleave ,  John K. Jackson ,  Rajesh Kumar Kainthan

发明人： Helen Burt ,  Donald Brooks ,  Jayachandran Kizhakkedathu ,  Richard Liggins ,  Dechi Guan ,  Lu Ye ,  Clement Mugabe ,  Alan So ,  Martin E. Gleave ,  John K. Jackson ,  Rajesh Kumar Kainthan

IPC分类号： A61K33/24 ,  C07C217/00 ,  C07D207/46 ,  A61K47/10 ,  A61K9/51 ,  A61K47/34 ,  C08G65/34 ,  C08G65/48 ,  C08G83/00 ,  C08G65/333 ,  A61K9/00

CPC分类号： A61K47/10 ,  A61K9/0034 ,  A61K9/006 ,  A61K9/5146 ,  A61K31/337 ,  A61K31/407 ,  A61K33/24 ,  A61K47/34 ,  A61K47/60 ,  C08G65/33306 ,  C08G65/33337 ,  C08G65/34 ,  C08G65/48 ,  C08G83/005 ,  C08G83/006 ,  C08G2650/54

摘要： Herein are provided derivatized hyperbranched polyglycerols (“dHPGs”). The dHPG comprises a core comprising a hyperbranched polyglycerol derivatized with C1C20 alkyl chains and a shell comprising at least one hydrophilic substituent bound to hydroxyl groups of the core, wherein the hyperbranched polyglycerol comprises from about 1 to about 200 moles of the at least one hydrophilic substituent. The dHPGs are for use as agents for the delivery of a drug or other biologically active moiety to the urinary tract, the digestive tract, the airways, the vaginal cavity and cervix and the peritoneal cavity to treat indications such as cancer, which may be useful in the treatment of or the manufacture of a medicament, in the preparation, of a pharmaceutical composition for the treatment of cancer, as a pre-treatment or co-treatment to improve drug uptake in a tissue. Furthermore, there are provided methods of making dHPGs.

摘要翻译： 本文提供衍生的超支化聚甘油（“dHPG”）。 dHPG包含核心，其包含用C1C20烷基链衍生的超支化聚甘油和包含至少一个与核心羟基结合的亲水取代基的壳，其中超支化聚甘油包含约1至约200摩尔的至少一个亲水取代基 。 dHPG用作将药物或其他生物活性部分递送至尿路，消化道，气道，阴道腔和子宫颈以及腹膜腔以治疗诸如癌症的适应症的药剂，其可能是有用的 在制备中用于治疗癌症的药物组合物的治疗或制造中，作为用于改善组织中药物摄取的预处理或共处理。 此外，还提供了制造dHPG的方法。

公开(公告)号：US09181374B2

公开(公告)日：2015-11-10

申请号：US14353112

申请日：2012-08-14

申请人： Bibiao Jiang ,  Wenyan Huang ,  Hongjun Yang ,  Xiaoqiang Xue

发明人： Bibiao Jiang ,  Wenyan Huang ,  Hongjun Yang ,  Xiaoqiang Xue

IPC分类号： C08F220/30 ,  C08F12/08 ,  C08G83/00 ,  C08F220/28 ,  C08L101/00

CPC分类号： C08F220/30 ,  C08F12/08 ,  C08F220/28 ,  C08G83/005 ,  C08L101/005 ,  C08F4/34 ,  C08F212/08 ,  C08F220/18 ,  C08F2220/281 ,  C08F218/08 ,  C08F220/14

摘要： A polymer synthesis process wherein a vinyl monomer, such as styrene, toluene (benzene, xylene) as a solvent, is subjected to a self-initiated free radical polymerization at 60˜100° C. with a compound (methyl(meth)acrylate peroxide) as the initiator and the branched monomer containing both polymerizable double bond and peroxide bond. The degree of branching of the polymer can be adjusted by adjusting the molar ratio of the compound to polymerizable monomer. The process for preparing a branched polymer is carried out under the conditions of conventional free radical polymerization without the addition of the branched monomer and other assist initiators.

摘要翻译： 聚合物合成方法，其中乙烯基单体如苯乙烯，甲苯（苯，二甲苯）作为溶剂，在60〜100℃下用化合物（（甲基）丙烯酸甲酯过氧化物）进行自引发的自由基聚合 ）作为引发剂和含有可聚合双键和过氧化物键的支化单体。 可以通过调节化合物与可聚合单体的摩尔比来调节聚合物的支化度。 制备支化聚合物的方法在常规自由基聚合的条件下进行，而不加入支化单体和其它辅助引发剂。