公开(公告)号：US4062976A

公开(公告)日：1977-12-13

申请号：US641730

申请日：1975-12-18

申请人： Edwin B. Michaels

发明人： Edwin B. Michaels

IPC分类号： A01N33/24 ,  A01N37/20 ,  A01N37/44 ,  A01N37/46 ,  A01N41/04 ,  A61K8/40 ,  A61K8/44 ,  A61K31/195 ,  A61K31/205 ,  A61Q5/02 ,  A61Q15/00 ,  A61Q19/10 ,  C11D1/75 ,  C11D1/94 ,  C11D3/00 ,  C11D3/48

CPC分类号： A61K8/40 ,  A01N33/24 ,  A01N37/20 ,  A01N37/44 ,  A01N37/46 ,  A01N41/04 ,  A61K31/205 ,  A61K8/44 ,  A61Q15/00 ,  A61Q17/005 ,  A61Q19/10 ,  A61Q5/02 ,  C11D1/75 ,  C11D1/94 ,  C11D3/0068 ,  C11D3/48

摘要： There is provided an antimicrobial composition of low toxicity having enhanced gram positive and gram negative activity and consists essentially of:A. An alkylsubstituted alanine (0.1 part - 40.0 parts, by weight),B. an alkyl-N,N-dimethylamine oxide, an alkyl-N,N-dihydroxyethylamine or an acylamido t-amine oxide (0.1 part - 40.0 parts, by weight), andC. a protonating agent, such as hydrochloric acid, acetic acid or citric acid, in an amount sufficient to adjust the pH of the overall composition to about 5.5 or below.The composition exhibits skin degerming, cleansing, and deodorizing properties and, particularly, its use exhibits long term inhibition of body odor.

摘要翻译： 提供了具有增强的革兰氏阳性和革兰氏阴性活性的低毒性的抗微生物组合物，其基本上由以下组成：

公开(公告)号：US4183952A

公开(公告)日：1980-01-15

申请号：US641729

申请日：1975-12-18

申请人： Edwin B. Michaels

发明人： Edwin B. Michaels

IPC分类号： A01N33/24 ,  A01N37/20 ,  A01N37/44 ,  A01N37/46 ,  A01N41/04 ,  A61K8/40 ,  A61K8/44 ,  A61K31/205 ,  A61Q5/02 ,  A61Q15/00 ,  A61Q19/10 ,  C11D1/75 ,  C11D1/94 ,  C11D3/00 ,  C11D3/48

CPC分类号： A61K8/40 ,  A01N33/24 ,  A01N37/20 ,  A01N37/44 ,  A01N37/46 ,  A01N41/04 ,  A61K31/205 ,  A61K8/44 ,  A61Q15/00 ,  A61Q17/005 ,  A61Q19/10 ,  A61Q5/02 ,  C11D1/75 ,  C11D1/94 ,  C11D3/0068 ,  C11D3/48

摘要： There is provided an antimicrobial composition of low toxicity having enhanced gram positive and gram negative activity and consists essentially of:(a) an alkyl-N-sulfobetaine (0.1 part-40.0 parts, by weight),(b) an alkyl-N,N-dimethylamine oxide, an alkyl-N,N-dihydroxyethylamine oxide, or an acylamido t-amine oxide (0.1 part-40.0 parts, by weight), and(c) a protonating agent, such as hydrochloric acid, acetic acid, in an amount sufficient to adjust the pH of the overall composition to about 5.5 or below.The composition exhibits skin degerming, cleansing, and deodorizing properties and, particularly, its use exhibits long term inhibition of body odor.

摘要翻译： 提供了具有增强的革兰氏阳性和革兰氏阴性活性的低毒性的抗微生物组合物，其基本上由以下组成：（a）烷基-N-磺基甜菜碱（0.1份-40.0份重量），（b）烷基-N， N-二甲基氧化胺，烷基-N，N-二羟基乙基胺氧化物或酰基酰胺基叔胺氧化物（0.1重量份〜40.0重量份），和（c）质子化剂如盐酸，乙酸， 足以将总体组合物的pH调节至约5.5或更低的量。 该组合物表现出皮肤脱皮，清洁和除臭特性，特别是其使用表现出长期抑制身体的气味。

公开(公告)号：US4107328A

公开(公告)日：1978-08-15

申请号：US800898

申请日：1977-05-26

申请人： Edwin B. Michaels

发明人： Edwin B. Michaels

IPC分类号： A01N33/24 ,  A01N37/20 ,  A01N37/44 ,  A01N37/46 ,  A01N41/04 ,  A61K8/40 ,  A61K8/44 ,  A61K31/205 ,  A61Q5/02 ,  A61Q15/00 ,  A61Q19/10 ,  C11D1/75 ,  C11D1/94 ,  C11D3/00 ,  C11D3/48 ,  A01N9/20

CPC分类号： A61K8/40 ,  A01N33/24 ,  A01N37/20 ,  A01N37/44 ,  A01N37/46 ,  A01N41/04 ,  A61K31/205 ,  A61K8/44 ,  A61Q15/00 ,  A61Q17/005 ,  A61Q19/10 ,  A61Q5/02 ,  C11D1/75 ,  C11D1/94 ,  C11D3/0068 ,  C11D3/48

摘要： There are provided antimicrobial compositions of the low toxicity having enhanced activity against gram positive and gram negative bacteria as well as fungi or protozoa and consists essentially of:(a) an alkyl-N-betaine in amounts up to 40 parts, by weight,(b) an alkyl-N,N-dimethylamine oxide, an alkyl-N,N-dihydroxy-ethylamine oxide, or an acylamido t-amine oxide in amounts up to 40 parts, by weight, and(c) a protonating agent, such as hydrochloric acid, acetic acid or citric acid in an amount sufficient to adjust the pH of the overall composition to from about 4.0 to about 5.5.The composition exhibits skin degerming, cleansing, and deodorizing properties and, particularly, its use exhibits long term inhibition of body odor.

摘要翻译： 提供了低毒性的抗微生物组合物，其对革兰氏阳性和革兰氏阴性细菌以及真菌或原生动物具有增强的活性，并且基本上由以下组成：

公开(公告)号：US4075350A

公开(公告)日：1978-02-21

申请号：US641728

申请日：1975-12-18

申请人： Edwin B. Michaels

发明人： Edwin B. Michaels

IPC分类号： A01N33/24 ,  A01N37/20 ,  A01N37/44 ,  A01N37/46 ,  A01N41/04 ,  A61K8/40 ,  A61K8/44 ,  A61K31/205 ,  A61Q5/02 ,  A61Q15/00 ,  A61Q19/10 ,  C11D1/75 ,  C11D1/94 ,  C11D3/00 ,  C11D3/48 ,  A61K31/13

CPC分类号： A61K8/40 ,  A01N33/24 ,  A01N37/20 ,  A01N37/44 ,  A01N37/46 ,  A01N41/04 ,  A61K31/205 ,  A61K8/44 ,  A61Q15/00 ,  A61Q17/005 ,  A61Q19/10 ,  A61Q5/02 ,  C11D1/75 ,  C11D1/94 ,  C11D3/0068 ,  C11D3/48

摘要： There is provided an antimicrobial composition of low toxicity having enhanced gram positive and gram negative activity and comprises:(a) an acyl-N-betaine (0.1 part - 40.0 parts, by weight),(b) an alkyl-N,N-dimethylamine oxide, an alkyl-N,N-dihydroxyethylamine oxide, or an acylamido t-amine oxide (0.1 part - 40.0 parts, by weight), and(c) a protonating agent, such as hydrochloric acid, acetic acid or citric acid in an amount sufficient to adjust the pH of the overall composition to about 5.5 or below.The composition exhibits deodorizing properties and, particularly, its use exhibits long term inhibition of body odor.

公开(公告)号：US4145436A

公开(公告)日：1979-03-20

申请号：US849031

申请日：1977-11-07

申请人： Edwin B. Michaels

发明人： Edwin B. Michaels

IPC分类号： A61K8/40 ,  A61K8/42 ,  A61K8/49 ,  A61K31/415 ,  A61Q15/00 ,  A61Q17/00

CPC分类号： A61Q15/00 ,  A61K31/415 ,  A61K8/40 ,  A61K8/42 ,  A61K8/4946 ,  A61Q17/005

摘要： There are provided antimicrobial compositions of the low toxicity having enhanced activity against gram positive and gram negative bacteria as well as fungi or protozoa and consists essentially of: (a) an alkylimidazolium betaine in amounts up to 40 parts, by weight, and (b) an alkyl-N,N-dimethylamine oxide, an alkyl-N,N-dihydroxyethylamine oxide, or an acrylamido t-amine oxide in amounts up to 40 parts, by weight. The composition exhibits skin degerming, cleansing, and deodorizing properties and, particularly, its use exhibits long term inhibition of body odor.