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公开(公告)号：US20220266053A1
公开(公告)日：2022-08-25
申请号：US17635571
申请日：2020-12-22
发明人： Takuya NANJO , Naoya ISHIBASHI
IPC分类号： A61N5/067
摘要： A phototherapy device includes a laser light source 8 for emitting laser light toward a target portion, a body part 5, an intake port 12 provided at a side surface of the body part 5, a discharge port 13 provided at the side surface of the body part 5 at an opposite side from the intake port 12, and an air supply device 14 for supplying air to be ejected from the intake port 12 to the inside of the body part 5, the intake port 12 configured so that an ejection direction FO of the air is toward the near side from a center of an emission area A of the laser light at the target portion T.
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公开(公告)号：US11344539B2
公开(公告)日：2022-05-31
申请号：US15998949
申请日：2017-02-17
申请人： NATIONAL UNIVERSITY CORPORATION TOTTORI UNIVERSITY , Takeshi Nishino , Ken Okamoto , Teijin Pharma Limited
发明人： Takeshi Nishino , Shinsuke Kato , Masako Kato , Hidenori Suzuki , Ken Okamoto
IPC分类号： A61K31/4439 , A61P25/28 , A61K9/00 , A61K31/426 , A61K31/427
摘要： The present invention provides a therapeutic agent or a prophylactic agent of dementia containing xanthine oxidase inhibitor such as a compound represented in formula (I), (II), (III) or (IV), or a pharmaceutically acceptable salt thereof as an active ingredient.
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公开(公告)号：US11338101B2
公开(公告)日：2022-05-24
申请号：US16497646
申请日：2018-03-19
发明人： Ryo Koizumi , Sadayoshi Matsumoto
IPC分类号： A61M16/00
摘要： An oxygen supply device supplying a user with an oxygen gas for inhalation acquires information of the user on percutaneous arterial oxygen saturation (SpO2) using a sensor unit, and calculates, from SpO2, the first moving average value and the second moving average value calculated over a time span longer than the first moving average in a control unit. The control unit calculates a Dip frequency during predetermined time from the SpO2 information, and when the calculated frequency is equal to or larger than the first threshold, the control unit switches the control from the control based on the first moving average value of SpO2 to the control based on the second moving average value.
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公开(公告)号：US11332459B2
公开(公告)日：2022-05-17
申请号：US16754349
申请日：2018-10-18
发明人： Michael D. Bartberger , Nagasree Chakka , Hua Gao , Angel Guzman-Perez , Daniel B. Horne , Zihao Hua , Madeleine Kieffer , Daniel C. H. Lin , Benjamin Charles Milgram , Jane Panteleev , Laurie Schenkel , John Stellwagen , Matthew Weiss , Ryan D. White , Wei Zhao
IPC分类号： C07D401/14 , A61K31/4545 , C07D401/04 , C07D403/04 , C07D413/14 , C07D471/04 , C07D471/10 , C07D498/04
摘要： The present invention relates to inhibitors of Transient Receptor Potential Channel 6 (TRPC6) protein activity. The present invention provides a compound of formula (I) or a pharmaceutically acceptable salt thereof, pharmaceutical compositions comprising a compound of the invention, a method for manufacturing compounds of the invention and therapeutic uses thereof.
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公开(公告)号：US20220001130A1
公开(公告)日：2022-01-06
申请号：US17293967
申请日：2019-11-14
发明人： Koichi SHINOHARA , Yuki YAMAURA
摘要： Provided is an oxygen concentration device, a control method, and a control program with which a start-up interval until a desired high-concentration oxygen gas can be supplied can be reduced. The oxygen concentration device includes a pressurized air supply unit for supplying pressurized air, an adsorption tube which concentrates oxygen in the pressurized air by adsorbing nitrogen in the supplied pressurized air to generate oxygen gas, an oxygen gas tank for storing oxygen gas, a flow rate adjustment unit which adjusts an oxygen gas flow rate to be output to the exterior from the oxygen gas tank, and a control unit which controls the flow rate adjustment unit so that the oxygen gas flow rate becomes a set flow rate and controls the pressurized air supply unit so that the pressurized air achieves a supply amount corresponding to the set flow rate.
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公开(公告)号：US20210380677A1
公开(公告)日：2021-12-09
申请号：US17122325
申请日：2020-12-15
发明人： Hiroshi Eguchi , Takashi Murakami , Naoko Namiki , Akira Tanokura , Jeanne E. Baker , Sophie Parmentier Batteur , Angela Marie Jablonski , Daniel Stephen Malashock , Carl Mieczkowski , Gopalan (Raghu) Raghunathan
摘要： The invention provides methods for using and compositions of humanized antibodies that bind tau protein that is phosphorylated at the serine at position 413.
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公开(公告)号：US20210379320A1
公开(公告)日：2021-12-09
申请号：US17287346
申请日：2019-09-25
发明人： Rei TAMIYA , Naoyuki IIDA , Shosaku MOTOHARA , Jun MATSUI
摘要： A nitric oxide administration device 1 includes a first flow path 101 including a first intake port 101a and an oxygen supply port 101b, an oxygen generation unit 100 which is arranged in the first flow path 101 and which generates concentrated oxygen from air introduced via the first intake port 101a, the generated concentrated oxygen being supplied via the oxygen supply port 101b, a second flow path 201 which is branched from the first flow path 101 and which includes an NO supply port 201b, and an NO generation unit 200 which is arranged in the second flow path 201 and which generates NO from gas distributed from the first flow path 101, the generated NO being supplied via the NO supply port 201b.
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公开(公告)号：US20210283355A1
公开(公告)日：2021-09-16
申请号：US16497646
申请日：2018-03-19
发明人： Ryo KOIZUMI , Sadayoshi MATSUMOTO
IPC分类号： A61M16/00
摘要： An oxygen supply device supplying a user with an oxygen gas for inhalation acquires information of the user on percutaneous arterial oxygen saturation (SpO2) using a sensor unit, and calculates, from SpO2, the first moving average value and the second moving average value calculated over a time span longer than the first moving average in a control unit. The control unit calculates a Dip frequency during predetermined time from the SpO2 information, and when the calculated frequency is equal to or larger than the first threshold, the control unit switches the control from the control based on the first moving average value of SpO2 to the control based on the second moving average value.
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公开(公告)号：US20210268308A1
公开(公告)日：2021-09-02
申请号：US17255208
申请日：2019-06-27
发明人： Naoya ISHIBASHI , Yuki KAWASE , Takuya NANJO , Takamitsu OKAYAMA
摘要： An object of the present invention is to provide a chair-type phototherapy device that enables a patient to perform light irradiation accurately targeted at a treatment site in a seated position on a chair and consequently achieves effective phototherapy even when the treatment site is in the back region that the patient is unable to see, for example, as in light irradiation for dysuria patients and patients with pain, and the patient performs light irradiation by himself/herself at home. The present invention provides a chair-type phototherapy device having a seat on which a patient is seated. The chair-type phototherapy device includes a radiation module configured to emit radiation light toward a living body, a drive module positioned behind the patient for moving the radiation module, and a fixing module fixing the drive module to the seat.
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公开(公告)号：US20210178014A1
公开(公告)日：2021-06-17
申请号：US17257500
申请日：2019-07-04
发明人： Tetsuya MOTOYOSHI , Ayuko YAMAGUCHI , Akitoshi OONO , Azusa MORI
IPC分类号： A61L24/04
摘要： The present invention is an endoscope hemostatic material comprising a sheet-like nonwoven fabric that is formed from a hydrophobic material that has a bulk density of 40 to 110 mg/cm3 and a film thickness of 400 to 1400 μm, and also an endoscope hemostatic material comprising a sheet-like nonwoven fabric that is formed from a hydrophobic material and that has an area density of 5.0 to 11.0 mg/cm3 and an average fiber diameter of 0.5 to 0.8 μm, either of which is suitable for treatment of bleeding through an endoscope.
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