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公开(公告)号：US4737139A
公开(公告)日：1988-04-12
申请号：US12411
申请日：1987-02-09
CPC分类号： A61M1/3627 , A61M1/325 , A61M1/3632 , Y10S128/03
摘要： A unitary device for the treatment and collection of blood from two different sources during a surgical procedure comprises a hollow housing made of a rigid, preferably transparent, material, first and second blood inlets in the housing, a first blood treatment element inside the housing comprising a layer of porous defoaming material and a layer of non-woven depth filter material, and a second blood treatment element inside the housing comprising a layer of porous defoaming material and free of any depth filter material. The novel device also includes internal walls for providing two blood flow paths therein, one through the first inlet, the first blood treatment element, a blood collection reservoir defined within the device and a treated blood outlet in the bottom wall of the housing, and the other through the second inlet, the second blood treatment element, the blood collection reservoir and the blood outlet. The latter blood flow path bypasses at least the depth filter material layer of the first blood treatment element. In typical use in an extracorporeal flow circuit, cardiotomy blood is introduced to the first inlet, venous return blood is introduced to the second inlet and the common blood outlet is connected to an extracorporeal blood pump. As a result, passage of the relatively clean venous return blood through a depth filter material is avoided.
摘要翻译： 用于在外科手术过程中用于处理和收集来自两种不同来源的血液的单一装置包括由刚性的，优选透明的材料制成的中空壳体，所述壳体中的第一和第二进血口，所述壳体内部的第一血液处理元件包括 一层多孔消泡材料和一层非织造深度过滤材料，以及第二血液处理元件，其内部包括多层消泡材料层并且没有任何深度过滤材料。 该新颖装置还包括用于在其中提供两个血液流动通道的内壁，一个穿过第一入口，第一血液处理元件，限定在该装置内的采血池，以及在该壳体的底壁中的经处理的血液出口， 其他通过第二入口，第二血液处理元件，采血池和血液出口。 后一血液流路至少绕过第一血液处理元件的深度过滤材料层。 在体外流路的典型用途中，将心脏切开血液引入第一入口，将静脉回流血液引入第二入口，共同血液出口连接到体外血泵。 结果，避免了相对干净的静脉血回流通过深度过滤材料。
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公开(公告)号：US4407777A
公开(公告)日：1983-10-04
申请号：US285797
申请日：1981-07-22
CPC分类号： A61M1/32 , A61M1/325 , A61M1/369 , Y10S128/03 , Y10S261/28
摘要： A blood oxygenator for one time use and discard in medical procedures. The blood oxygenator has a unitary transparent sealed vessel with first and second blood treating stages arranged for series flow. The first stage receives an inflow of blood and oxygen and it has integrated oxygenating and heat exchanging elements that include a plurality of vertical ribs and flutes internested to provide upright thin-film blood and oxygen flow channels. These ribs and flutes surround, by a common wall, a heat exchanger with upright channels for counter-directional coolant flow relative to the blood and oxygen flow. The second stage has integrated blood degassing and defoaming elements including a vertical perforated wall surrounded by a porous foam member with a surrounding reservoir of outflowing degassed and defoamed blood and a vent for free oxygen gas.
摘要翻译： 血液充氧器一次性用于医疗程序。 血液充氧器具有单一的透明密封容器，其具有排列成串联流动的第一和第二血液处理级。 第一阶段接收血液和氧气的流入，并且其具有整合的氧化和热交换元件，其包括多个垂直肋和槽纹，以提供直立的薄膜血液和氧气流动通道。 这些肋和沟槽通过公共壁围绕具有用于相对于血液和氧气流动的相反方向冷却剂流动的直立通道的热交换器。 第二阶段包括血液脱气和消泡元件，包括由多孔泡沫构件包围的垂直穿孔壁和周围的流出脱气和消泡血液的储存器和用于游离氧气的排气口。
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公开(公告)号：US4372914A
公开(公告)日：1983-02-08
申请号：US257885
申请日：1981-04-27
申请人： Donald A. Raible
发明人： Donald A. Raible
CPC分类号： A61M1/32 , A61M1/325 , A61M1/369 , Y10S128/03 , Y10S261/28
摘要： A blood oxygenating device having an oxygenating chamber and a heat exchange chamber. The oxygenating chamber consists of a bubbler chamber and a mixing chamber. Oxygen is introduced into the bubbler chamber through a porous diffusion means situated near the inlet of the bubbler chamber. Bubbles pass from the bubbler chamber into a mixing chamber which is provided with a plurality of secondary flow-producing deflectors to promote secondary flow of blood bubbles passing therethrough. The secondary flow results in a highly efficient oxygen-carbon dioxide transfer. The blood bubbles are then passed through a heat exchange chamber and a defoaming means prior to exiting the oxygenating device.
摘要翻译： 一种具有氧合室和热交换室的血液充氧装置。 氧合室由起泡室和混合室组成。 通过位于起泡器入口附近的多孔扩散装置将氧气引入起泡室中。 气泡从起泡室进入混合室，该混合室设置有多个二次流产生偏转器，以促进通过其中的血液二次流动。 二次流动导致高效的氧 - 二氧化碳转移。 然后在离开氧合装置之前，血液气泡通过热交换室和消泡装置。
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公开(公告)号：US4297318A
公开(公告)日：1981-10-27
申请号：US54268
申请日：1979-07-02
申请人： Donald A. Raible
发明人： Donald A. Raible
CPC分类号： A61M1/32 , A61M1/325 , A61M1/369 , Y10S128/03 , Y10S261/28
摘要： A blood oxygenating device comprising an oxygenating chamber and a heat exchange chamber, the oxygenating chamber comprising a bubbler chamber and a mixing chamber. Oxygen is introduced into the bubbler chamber through a porous diffusion means situated near the inlet of the bubbler chamber. Bubbles pass from the bubbler chamber into the mixing chamber which is provided with a plurality of secondary flow-producing deflectors to promote secondary flow and rotation of blood bubbles passing therethrough. The secondary flow results in a highly efficient oxygen-carbon dioxide transfer. The blood bubbles are then passed through a heat exchange chamber and a defoaming means prior to exiting the oxygenating device.In a preferred version, blood and oxygen-rich gas are admitted at the top of the device and caused to flow substantially downwardly through a tortuous path which causes at least a portion of the blood bubbles to rotate. During the course of downward flow, the blood-gas-bubble mixture passes around a heat exchange device, which preferably is convoluted, helically wound tubing so as to form the tortuous path, to bring the blood to a desired temperature. The oxygenator is equipped with a defoaming means such that the blood bubbles are converted back into liquid blood, which is then returned to the patient. Vent means are provided for removal of carbon dioxide and other vent gases. Means for promoting secondary flow in the blood are preferably provided in the upward region of the oxygenator.
摘要翻译： 一种包含氧合室和热交换室的血液充氧装置，所述充氧室包括起泡室和混合室。 通过位于起泡器入口附近的多孔扩散装置将氧气引入起泡室中。 气泡从起泡室进入混合室，混合室设有多个二次流产生偏转器，以促进通过其中的血液二次流动和旋转。 二次流动导致高效的氧 - 二氧化碳转移。 然后在离开氧合装置之前，血液气泡通过热交换室和消泡装置。 在优选的方案中，血液和富氧气体在装置的顶部进入，并使其大致向下流过通过弯曲的路径，这导致至少一部分血液气泡旋转。 在向下流动的过程中，血液 - 气体 - 气泡混合物绕过热交换装置，该热交换装置优选是回旋的，螺旋形缠绕的管道以形成曲折路径，以使血液达到所需温度。 氧合器配备有消泡装置，使得血液气泡被转换成液体血液，然后将其返回到患者体内。 提供排气装置用于去除二氧化碳和其他排放气体。 用于促进血液中二次流动的方法优选设置在氧合器的向上区域中。
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公开(公告)号：US4208193A
公开(公告)日：1980-06-17
申请号：US959113
申请日：1978-11-09
申请人： John M. Munsch , Ludwig Wolf, Jr.
发明人： John M. Munsch , Ludwig Wolf, Jr.
CPC分类号： A61M1/3627 , A61M1/325
摘要： A blood reservoir comprises a rigid casing and a perforated tubular member positioned within the casing and extending between the edges thereof. An inlet aperture is at a position at the upper end of the reservoir in communication with the bore of the tubular member while an outlet aperture is positioned adjacent the bottom of the casing exterior to the tubular member. The bore of the tubular member contains first blood-defoaming means, and the tubular member carries a blood filter. In accordance with this invention, second blood defoaming means are positioned about the exterior of the tubular member to dissipate the fine bubbles without interference from the larger bubbles, which have been previously removed by passage through the first blood defoaming means.
摘要翻译： 血液贮存器包括刚性壳体和定位在壳体内并在其边缘之间延伸的多孔管状构件。 入口孔位于储存器的上端处与管状构件的孔连通的位置，同时出口孔邻近管状构件外部的壳体的底部定位。 管状构件的孔包含第一血液消泡装置，并且管状构件携带血液过滤器。 根据本发明，第二血液消泡装置围绕管状构件的外部定位，以消散细小气泡，而不受来自通过第一血液消泡装置的先前去除的较大气泡的干扰。
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公开(公告)号：US4205042A
公开(公告)日：1980-05-27
申请号：US918359
申请日：1978-06-23
CPC分类号： A61M1/32 , A61M1/325 , A61M1/3624 , A61M39/10 , A61M1/369 , A61M2205/3389 , A61M5/40 , Y10S128/03
摘要： A blood oxygenator with an oxygen filter in the oxygen inlet chamber, featuring in a particular aspect elevating the filter above the diffuser plug of the oxygenator.
摘要翻译： 在氧气进气室中具有氧气过滤器的血氧饱和器，其特征在于使过氧化物在氧合器的扩散器塞上方升高。
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公开(公告)号：US3993461A
公开(公告)日：1976-11-23
申请号：US531018
申请日：1974-12-09
CPC分类号： A61M1/3627 , A61M1/325 , B01D19/02
摘要： A reservoir for the collection, purification, and storage of blood during surgical procedures which comprises a hollow blood storage casing having a hollow, perforated member within said casing extending from end-to-end thereof. Blood defoaming means and a filter are carried by the hollow member, so that the blood defoamer and filter are noncollapsible, and extend the entire length of the chamber within the casing, with one of the ports communicating with the interior of the hollow member, so that blood passes through the perforations of the hollow member and defoamer-filter means.
摘要翻译： 一种用于在外科手术过程中收集，净化和储存血液的储存器，其包括在所述外壳内具有中空的穿孔构件的空心血液储存壳体，其从端到端延伸。 血液消泡装置和过滤器由中空构件承载，使得消泡剂和过滤器不可拆卸，并且在壳体内延伸室的整个长度，其中一个端口与中空构件的内部连通，因此 血液通过中空构件和消泡剂过滤装置的穿孔。
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公开(公告)号：US3827860A
公开(公告)日：1974-08-06
申请号：US26304972
申请日：1972-06-15
发明人： BURLIS N
CPC分类号： A61M1/32 , A61M1/325 , Y10S128/03 , Y10S261/28
摘要： A BUBBLE OXYGENATION DEVICE WHICH INCLUDES A CYLINDRICAL OXYGENATORR CHAMBER CONNECTED IN SERIES WITH A DEFOAMING CHAMBER AD A SETTLING CHAMBER, AND AN OXYGEN DISPERSER MEMBER FOR DELIVERING OXYGEN AND VENOUS BLOOD TO THE OXYGENATOR CHAMBER, THE DISPERSER MEMBER BEING SLIDABLE IN THE OXYGENATOR TO CONTROL THE OXYGENATION CAPACITY THEREOF.
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公开(公告)号：US3256883A
公开(公告)日：1966-06-21
申请号：US30075763
申请日：1963-08-08
申请人： DE WALL RICHARD A
发明人： DE WALL RICHARD A
IPC分类号： A61M1/32
CPC分类号： A61M1/32 , A61M1/325 , Y10S261/28
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公开(公告)号：US3175555A
公开(公告)日：1965-03-30
申请号：US22542362
申请日：1962-09-21
申请人： ABBOTT LAB
发明人： LING WILFRED C
IPC分类号： A61M1/32
CPC分类号： A61M1/32 , A61M1/325 , Y10S128/03
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