公开(公告)号：US20170281943A1

公开(公告)日：2017-10-05

申请号：US15084189

申请日：2016-03-29

申请人： Warsaw Orthopedic, Inc

发明人： Tyler S. Stevenson ,  Richard L. Brown ,  Todd A. Kallmyer ,  Matthew M. Morrison ,  Sneha Saikia ,  Randal Schulhauser

IPC分类号： A61N1/36 ,  A61N1/378

CPC分类号： A61N1/36035 ,  A61N1/05 ,  A61N1/205 ,  A61N1/326 ,  A61N1/378 ,  A61N1/3787

摘要： A bone growth simulator system. A bioabsorbable electric circuit is encapsulated in a modified alginate known-time dissolving capsule having a rate of dissolving proportional to the thickness of the capsule. The electronic circuit is powered by a power source. The power source can be inside the capsule or outside the capsule, and can be bioabsorbable or at least biocompatible. An operational amplifier maintains constant current through the circuit. The current stimulates bone growth in bones adjacent to the circuit. The capsule and electric circuit dissolve after completion of the therapy.

公开(公告)号：US4553548A

公开(公告)日：1985-11-19

申请号：US524851

申请日：1983-08-19

申请人： Anthony J. Varrichio ,  Pat L. Gordon

发明人： Anthony J. Varrichio ,  Pat L. Gordon

IPC分类号： A61N1/08 ,  A61N1/36 ,  A61N1/00

CPC分类号： A61N1/36035 ,  A61N1/08

摘要： An interrogator for remotely interrogating an internal counter of a scoliosis treatment device. An internal counter of the treatment device is incremented for those periods of time in which the treatment level of the device is in excess of a compliance level. The interrogator communicates with the internal counter by means of two serial data lines. On one data line the interrogator generates a clock signal to the internal counter for incrementing the device and on the other data line the interrogator receives a pulse indicating the internal counter has overflowed. By incrementing the internal counter through a full cycle of its maximum count the counter will retain the count present when it is interrogated. Additionally, by counting the number of, clock counts comprising the period from the overflow signal to the end of a full cycle a duplication of the count in the remote internal counter can be stored in the interrogator and subsequently displayed.

摘要翻译： 用于远程询问脊柱侧弯治疗装置的内部计数器的询问器。 治疗装置的内部计数器在设备的治疗水平超过合规水平的那段时间内递增。 询问器通过两条串行数据线与内部计数器通信。 在一条数据线上，询问器产生一个时钟信号给内部计数器，用于递增器件，另一条数据线上，询问器接收一个指示内部计数器溢出的脉冲。 通过在其最大计数的整个周期内递增内部计数器，计数器将保留当询问时存在的计数。 此外，通过计数包括从溢出信号到完整周期结束的周期的时钟计数的数量，远程内部计数器中的计数的重复可以存储在询问器中并随后显示。

公开(公告)号：US4342317A

公开(公告)日：1982-08-03

申请号：US136310

申请日：1980-04-01

申请人： Jens Axelgaard

发明人： Jens Axelgaard

IPC分类号： A61N1/36

CPC分类号： A61N1/36035

摘要： This disclosure is directed to an improved method of correction of spinal curvature deficiencies such as scoliosis, lordosis, kyphosis and combinations thereof, utilizing transcutaneous, percutaneous or subcutaneous electrical muscle stimulation of certain target musculature. The improvements reside in the use first of techniques (preferably thermographic) to define pairs of non-overlapping sites of muscle contraction (when electrically stimulated by a predetermined electrical pulse pattern) which sites of muscle contraction surround the reference center or apex of the major curvature to be corrected. Following selection of the muscle sites, one supplies electrical muscle stimulation to each of the muscle sites to be contracted, on an alternating basis, the net effect of which is that the muscle sites jointly apply a corrective force on a constant basis while, at the same time, each said muscle site has a rest period between each stimulation period. Each muscle site is not affected by the electrical stimulation of the other site. The method for applying dual channel alternating stimulation of target muscle sites, which are non-overlapping during stimulation, results in a constant force being applied on the curvature to be reduced without the muscle fatigue which would normally be associated with stimulation of a single muscle site on a constant basis. It appears that the treatment using the above-described techniques of dualchannel alternating stimulation of separate muscle sites which are first carefully defined, as by thermographic mapping, is a substantially more efficient way of hastening reduction of scoliotic, and other spinal, curvature deficiencies.

摘要翻译： 本公开涉及一种利用经皮皮肤，皮下或皮下电刺激某些目标肌肉组织来矫正脊柱弯曲不足的改良方法，例如脊柱侧凸，脊柱前凸，脊柱后凸及其组合。 改进在于首先使用技术（优选热成像术）来定义肌肉收缩的非重叠位置对（当由预定的电脉冲图形电刺激时）肌肉收缩的位置围绕参考中心或主曲率的顶点 要纠正 在选择肌肉部位之后，一个供应肌肉肌肉的每一个肌肉部位，以交替的方式进行收缩，其净效果是肌肉部位在恒定的基础上联合应用矫正力，而在 同时，每个肌肉网站每个刺激期间都有休息期。 每个肌肉部位不受其他部位的电刺激的影响。 在刺激期间施加不重叠的靶肌肉部位的双通道交替刺激的方法导致在要减少的曲率上施加恒定的力，而不会产生通常与单个肌肉部位的刺激相关的肌肉疲劳 在不断的基础上。 看起来，使用上述技术的双通道交替刺激单独肌肉部位的技术首先被精心定义，如通过热成像测绘法，是加速脊柱侧凸和其他脊柱曲率缺陷减轻的一种更有效的方法。

公开(公告)号：US4026301A

公开(公告)日：1977-05-31

申请号：US569842

申请日：1975-04-21

申请人： Harry G. Friedman ,  Robert W. Wickham, Jr.

发明人： Harry G. Friedman ,  Robert W. Wickham, Jr.

IPC分类号： A61N1/04 ,  A61B17/70 ,  A61N1/05 ,  A61N1/32 ,  A61N1/36

CPC分类号： A61N1/36035 ,  A61B17/70

摘要： A system for the electrical treatment of spinal curvature through the exercise of selected spinal muscles. A probe having a blunt, muscle-penetrating tip is fitted with a sleeve such that its tip extends from the sleeve. A helical electrode is mounted on an elongated tool capable of imparting a rotational force to the electrode while allowing a disengagement with the electrode in the direction of its longitudinal axis. The probe is inserted in the paraspinal muscles and is removed while leaving the sleeve within the muscle. The electrode-tool assembly is inserted through the sleeve and the electrode secured in the paraspinal muscles by a rotational force applied to the tool. After electrode securement, the tool is withdrawn from the sleeve and the sleeve withdrawn from the muscle leaving the electrode secured within the muscle. Needle electrodes may be employed to stimulate the paraspinal muscles at several sites to establish those sites at which the induced muscle contraction provides maximum correction of the spinal curvature and the blunt probe tip may be provided with an electrode for muscle stimulation at varied penetration depths to establish the optimum depth for securement of the helical electrode.The electrodes are connected by leads to a receiver circuit implantable beneath the patient's skin and operable to receive RF modulated stimulation impulses transmitted through the skin. The impulses are developed by a patient operated RF transmitter with a cyclic on and off stimulation and rest periods so that stimulation of the muscles may take place while the patient relaxes or sleeps.

摘要翻译： 通过运动选择的脊髓肌肉进行脊柱弯曲的电疗治疗系统。 具有钝的肌肉穿透尖端的探针装配有套筒，使得其尖端从套筒延伸。 螺旋电极安装在能够向电极施加旋转力的细长工具上，同时允许电极沿其纵向轴线的方向脱离。 将探头插入椎旁肌肉中，并将其保持在肌肉内部。 电极工具组件通过套筒插入，电极通过施加到工具的旋转力固定在椎旁肌中。 在电极固定之后，工具从套筒中取出，并且从肌肉中取出的套管将电极固定在肌肉内。 可以使用针电极来刺激几个部位的脊柱肌，以建立诱导的肌肉收缩提供脊柱弯曲的最大校正的位置，并且钝头探针尖端可以设置有用于在不同穿透深度处进行肌肉刺激的电极，以建立 用于固定螺旋电极的最佳深度。

公开(公告)号：US6027521A

公开(公告)日：2000-02-22

申请号：US247991

申请日：1999-02-11

申请人： Rosemarie A. Ourada

发明人： Rosemarie A. Ourada

IPC分类号： A61B17/00 ,  A61B17/132 ,  A61N1/36

CPC分类号： A61N1/36035 ,  A61B17/00 ,  A61B17/1325

摘要： A behavior modification reinforcement bracelet for providing mildly painful stimuli to a user when the user thinks about or performs a behavior that the user wishes to change. The behavior modification reinforcement bracelet includes an elastic annular band with opposite inwards and outwards faces, and a pair of side edges. A plurality of stimuli regions are provided on the band. Each of the stimuli regions has a plurality of nubs extending in a radially inwards direction from the inwards face of the band.

摘要翻译： 一种行为修改加固手链，用于在用户想到或执行用户希望改变的行为时向用户提供轻度痛苦的刺激。 行为修改加固手镯包括一个弹性环带，内侧和外侧相对的一个弹性环带和一对侧边。 在该带上设置多个刺激区域。 每个刺激区域具有从带的向内面沿径向向内方向延伸的多个凸起部。

公开(公告)号：US4326534A

公开(公告)日：1982-04-27

申请号：US50760

申请日：1979-06-21

申请人： Jens Axelgaard ,  David C. Howson ,  John A. Perhay

发明人： Jens Axelgaard ,  David C. Howson ,  John A. Perhay

IPC分类号： A61N1/36

CPC分类号： A61N1/36035

摘要： A method and apparatus for treatment of spinal deformities, for example, scoliosis, in which a muscle stimulator (pulse generator) is used to apply a preferred form of stimulating impulses to a patient so as to involuntarily cause contraction of particular selected trunk muscle groups to thereby effect a curvature correcting movement of selected spinal vertebrae while minimizing undesirable side effects, such as muscle fatigue. A first integrated circuit timer establishes a selectively variable "on-time" for a burst of pulses while a second such timer sets the "off-time" or interval between bursts. The individual pulses in the burst are initially of narrow width, but succeeding pulses in the group are of increasing width up to a predetermined maximum which maximum level is maintained for a desired time ("hold-time") prior to the termination of the burst. In an alternative embodiment, the stimulating impulses may be gradually decreased in width immediately prior to the pulse generator's effective "off-time". It has been determined that this pattern of stimulating pulses, when applied via body contacting electrodes positioned proximate the trunk muscle groups judiciously selected and determined by observations of the spinal curve to be corrected, has particular efficacy in the treatment of scoliosis, kyphosis, lordosis and combinations thereof.

摘要翻译： 用于治疗脊柱畸形（例如脊柱侧凸）的方法和装置，其中使用肌肉刺激器（脉冲发生器）将优选形式的刺激脉冲应用于患者，以便不经意地引起特定选择的躯干肌群的收缩 从而影响所选择的脊椎椎体的曲率校正运动，同时最小化不期望的副作用，例如肌肉疲劳。 第一集成电路定时器为脉冲串建立选择性变量“接通时间”，而第二个这样的定时器设置突发之间的“关闭时间”或间隔。 突发中的单个脉冲最初是窄的宽度，但组中后续的脉冲具有增加的宽度直到预定的最大值，在突发结束之前的期望时间（“保持时间”）保持最大电平 。 在替代实施例中，紧接在脉冲发生器有效的“关闭时间”之前，刺激脉冲的宽度可以逐渐减小。 已经确定，通过身体接触电极施加的刺激脉冲模式，通过正确地选择并通过观察要校正的脊柱曲线来确定的身体接触电极，在治疗脊柱侧凸，脊柱后凸，脊柱前凸和 其组合。

公开(公告)号：US3983881A

公开(公告)日：1976-10-05

申请号：US579506

申请日：1975-05-21

申请人： Geoffrey Gordon Wickham

发明人： Geoffrey Gordon Wickham

IPC分类号： A61N1/36

CPC分类号： A61N1/36035

摘要： An improved muscle stimulator, particularly suited to long term rhythmic stimulation for the selective development of musculature otherwise asymmetric or retarded in relative development. To minimize the subjects' awareness of stimulation, to permit nocturnal use, and to minimize battery consumption, the energy content of each pulse train is modulated by a progressive increase of pulse width up to a maximum, followed by a progressive decrease of pulse width, thus yielding a gradual contraction and relaxation of the muscle.

公开(公告)号：US5643329A

公开(公告)日：1997-07-01

申请号：US545958

申请日：1995-10-20

申请人： Moshe Solomonow ,  Robert D'Ambrosia

发明人： Moshe Solomonow ,  Robert D'Ambrosia

IPC分类号： A61N1/36 ,  A61N1/18

CPC分类号： A61N1/36035

摘要： A system for maintaining a desired spinal curvature of a user suffering from improper alignment of the vertebrae of the spine. In it's broad aspects, it comprises a sensor feedback system and electrodes. The sensor feedback system measures spinal curvature, determines whether selected conditions have been met warranting the application of electrical stimulation and provides information regarding the determination to an electronic stimulator. The electrodes are spaceably mounted on selected portions of the user's back. They are in electrical communication with the electronic stimulator for causing contraction of the back muscles at selected levels, thus providing alignment of the spinal vertebrae. The sensor feedback system includes a sensor assembly which comprises an upper elongated rigid segment, a lower elongated rigid segment and a sensor. The upper elongated rigid segment is positionable adjacent the user's upper spine. The lower elongated rigid segment is positionable adjacent the posterior pelvic region. The sensor is mounted on a flexible middle segment between the upper segment and the lower segment. The sensor is so positioned as to measure lordosis.

摘要翻译： 一种用于维持患者脊柱的椎骨不适当对准的期望的脊柱弯曲的系统。 在广泛的方面，它包括传感器反馈系统和电极。 传感器反馈系统测量脊柱曲率，确定所选条件是否得到满足，保证应用电刺激，并向电子刺激器提供关于确定的信息。 电极可空间地安装在用户背部的选定部分上。 它们与电子刺激器电气通信，用于引起背部肌肉在选定水平的收缩，从而提供脊椎的对准。 传感器反馈系统包括传感器组件，其包括上部细长刚性段，下部细长刚性段和传感器。 上部细长的刚性段可定位成邻近使用者的上脊。 下部细长的刚性段可邻近后部骨盆区域定位。 传感器安装在上段和下段之间的柔性中段上。 传感器位置适于测量脊柱前凸。

公开(公告)号：US4830009A

公开(公告)日：1989-05-16

申请号：US844351

申请日：1986-03-26

申请人： Otmar Schmitt ,  Heinz Mittelmeier

发明人： Otmar Schmitt ,  Heinz Mittelmeier

IPC分类号： A61N1/36

CPC分类号： A61N1/36035

摘要： The apparatus for electrical stimulation is more particularly adapted for the treatment of scoliosis and comprises an electrical circuit which delivers individual pulses having a duration of about 1 ms, an amplitude of about 150 V, a constant current intensity of about 75 mA and a frequency of 100 Hz as well as series of pulses with rising amplitude and a ramp up phase of about 2 s, followed by holding phase of about 2 s and a time off between two series of pulses of about 10 s. The apparatus further comprises three channels, whereby the first channel is applied on the side of the curvature, the second channel on the side of the counter curvature and the third channel on the abdominal musculature, whereby all channels are fed simultaneously.

摘要翻译： 用于电刺激的装置更特别地适用于治疗脊柱侧凸，并且包括电路，该电路传递具有约1ms的持续时间，约150V的振幅，约75mA的恒定电流强度和 100 Hz以及具有上升幅度和斜坡上升相位约2 s的脉冲序列，然后保持约2 s的相位和约10 s的两个脉冲串之间的时间间隔。 该装置还包括三个通道，其中第一通道被施加在曲率侧，第二通道在相对曲率侧，第二通道位于腹部肌肉组织上，由此所有通道同时进给。

公开(公告)号：US4539993A

公开(公告)日：1985-09-10

申请号：US442532

申请日：1982-11-18

申请人： David J. Stanton

发明人： David J. Stanton

IPC分类号： A61N1/36

CPC分类号： A61N1/36035

摘要： A tissue stimulator of the type which provides short intervals of stimulation followed by longer intervals of rest is provided with a fail-safe system for turning off the stimulator if the stimulation interval exceeds a predetermined maximum interval. A timer times each "on" interval. If the "on" interval exceeds the predetermined maximum, the timer times out and shuts off stimulation.

摘要翻译： 如果刺激间隔超过预定的最大间隔，则提供了一种提供较短间隔刺激随后更长间隔休息的组织刺激器，该故障安全系统用于关闭刺激器。 一个定时器对每个“开”间隔进行计时。 如果“开”间隔超过预定最大值，定时器超时并关闭刺激。