公开(公告)号：US20240175066A1

公开(公告)日：2024-05-30

申请号：US18551182

申请日：2022-03-18

Applicant: AMYRIS , INC.

Inventor： Nathaniel KREFMAN ,  Lauren RAETZ ,  Elizabeth ZNAMERROSKI

IPC: C12P19/44 ,  C12N1/18 ,  C12N9/02 ,  C12N9/10 ,  C12N9/12 ,  C12N9/88 ,  C12N15/52 ,  C12P7/24

CPC classification number: C12P19/44 ,  C12N1/185 ,  C12N9/0008 ,  C12N9/1011 ,  C12N9/1051 ,  C12N9/1085 ,  C12N9/1288 ,  C12N9/88 ,  C12N15/52 ,  C12P7/24 ,  C12Y102/0103 ,  C12Y201/01114 ,  C12Y204/01126 ,  C12Y205/01054 ,  C12Y207/08007 ,  C12Y402/0101 ,  C12Y402/01118

Abstract: Provided herein are genetically modified host cells. compositions. and methods for improved production of vanillin and/or glucovanillin. The host cells. compositions. and methods described herein provide an efficient route for the heterologous production of vanillin and/or glucovanillin and any compound that can be synthesized or biosynthesized from either or both.