公开(公告)号：US11999961B2

公开(公告)日：2024-06-04

申请号：US17830072

申请日：2022-06-01

申请人： Altria Client Services LLC

发明人： Chengalrayan Kudithipudi ,  Dongmei Xu ,  James Strickland ,  Yanxin Shen

IPC分类号： C12N15/82 ,  A01H6/82 ,  A24B13/00 ,  A24B15/10 ,  A24B15/24

CPC分类号： C12N15/8243 ,  A01H6/823 ,  A24B13/00 ,  A24B15/10 ,  A24B15/245 ,  C12N15/8251 ,  C12Y402/01091

摘要： The present disclosure provides approaches for reducing tobacco-specific nitrosamines (TSNAs) in tobacco. Some of these approaches include genetically engineering tobacco plants to increase one or more antioxidants, increase oxygen radicle absorbance capacity (ORAC), increase phenylalanine, or reduce nitrite. Also provided are methods and compositions for producing modified tobacco plants and tobacco products therefrom comprising reduced TSNAs.