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公开(公告)号:US07462698B2
公开(公告)日:2008-12-09
申请号:US11492498
申请日:2006-07-24
申请人: Teikichi Aoyagi , Peter Peizhi Luo , Pingyu Zhong , Mark Hsieh , Yan Li , Kevin Caili Wang , Chikao Morimoto
发明人: Teikichi Aoyagi , Peter Peizhi Luo , Pingyu Zhong , Mark Hsieh , Yan Li , Kevin Caili Wang , Chikao Morimoto
IPC分类号: C12P21/08 , C07K16/00 , A61K35/395 , A61K39/00
CPC分类号: C07K16/2896 , A61K38/00 , A61K2039/505 , C07K2317/24 , C07K2317/34 , C07K2317/55 , C07K2317/56 , C07K2317/565 , C07K2317/567 , C07K2317/73 , C07K2317/92 , G01N33/574 , G01N2333/70596 , G01N2500/00 , Y02A50/473
摘要: The present invention provides novel anti-CD26 antibodies and other, related polypeptides, as well as novel polynucleotides encoding the antibodies and polypeptides. The invention also provides methods of making the antibodies and polypeptides. Compositions and cells comprising the antibodies or polypeptides are further provided. Methods of using the antibodies and/or polypeptides, such as to inhibit cell proliferation and in the treatment of conditions associated with CD26, are also provided.
摘要翻译: 本发明提供新的抗CD26抗体和其它相关多肽,以及编码抗体和多肽的新型多核苷酸。 本发明还提供了制备抗体和多肽的方法。 进一步提供包含抗体或多肽的组合物和细胞。 还提供了使用抗体和/或多肽的方法,例如抑制细胞增殖和治疗与CD26相关的病症。