公开(公告)号：US20020124923A1

公开(公告)日：2002-09-12

申请号：US10034104

申请日：2001-12-20

Applicant: Michelin Recherche et Technique S.A.

Inventor： Richard Abinal ,  Thomas Emberger ,  Jean-Pierre Pompier

IPC: B60B007/01

CPC classification number: B60B21/023 ,  B60B21/026 ,  B60B21/028 ,  B60B21/102 ,  B60B21/104 ,  B60B21/12 ,  B60C15/0236 ,  B60C15/0247 ,  B60C17/06 ,  B60C2017/068

Abstract: An assembly including a deformable, inextensible tread-bearing support S, which can be slipped on to a suitable rim bearing surface (11). The bearing surface (11) extends axially towards the inside of a first rim seat (13null), which is in turn extended to the outside by a protrusion or hump (15null) of low height. The first rim seat (13null) is inclined towards the outside. A second rim seat (13null) having, viewed in meridian section, a generatrix, the axially inner end of which is located on a circle of diameter DnullA greater than the diameter of the circle on which is located the axially inner end DnullA of the first rim seat (13null). The two seats being, axially to the inside, extended by frustoconical portions (17, 14) of a height at least equal to 0.01 times the minimum diameter of the bearing surface (11), and the generatrices of which form with the axis of rotation angles null at least equal to 45null. The rim bearing surface (11) is provided with at least one circumferential protuberance (115) arranged in a circumferential groove (30) of the radially inner face of the tread bearing support S, such that the protuberance (115) axially comes to bear and butt up against at least one lateral wall of the groove (30).

Abstract translation: 包括可变形的不可伸展的胎面支承件S的组件，其可滑动到合适的轮辋支承表面（11）上。 轴承表面（11）轴向延伸到第一边缘座（13'）的内部，第一边缘座（13'）又由低高度的突起或隆起（15'）延伸到外部。 第一轮辋座（13'）向外倾斜。 在子午线部分中观察到的第二轮辋座椅（13“），母线的轴向内端位于直径D”A的圆上，该直径大于圆的直径，其中轴线内 第一轮辋座（13'）的末端D'A。 所述两个座部沿轴向向内延伸，其截面圆锥形部分（17,14）的高度至少等于所述支承表面（11）的最小直径的0.01倍，并且所述母线与所述旋转轴线形成 角度α至少等于45°。 轮辋轴承表面（11）设置有至少一个周向突起（115），其布置在胎面支承支撑件S的径向内表面的周向凹槽（30）中，使得凸起（115）轴向承受，并且 与凹槽（30）的至少一个侧壁对接。

公开(公告)号：US20040145233A1

公开(公告)日：2004-07-29

申请号：US10350033

申请日：2003-01-24

Applicant: Kuan Hsings Enterprise Corp.

Inventor： Ming Fang Wang

IPC: B60B007/01

CPC classification number: B60B7/12

Abstract: Methods and vectors (both DNA and retroviral) are provided for the construction of a Library of mutated cells. The Library will preferably contain mutations in essentially all genes present in the genome of the cells. The nature of the Library and the vectors allow for methods of screening for mutations in specific genes, and for gathering nucleotide sequence data from each mutated gene to provide a database of tagged gene sequences. Such a database provides a means to access the individual mutant cell clones contained in the Library. The invention includes the described Library, methods of making the same, and vectors used to construct the Library. Methods are also provided for accessing individual parts of the Library either by sequence or by pooling and screening. The invention also provides for the generation of non-human transgenic animals which are mutant for specific genes as isolated and generated from the cells of the Library.

Abstract translation: 提供方法和载体（DNA和逆转录病毒）用于构建突变细胞库。 该文库优选地在基因组中存在基因组中所有基因的突变。 图书馆和载体的性质允许筛选特定基因突变的方法，并收集每个突变基因的核苷酸序列数据，以提供标记基因序列的数据库。 这样的数据库提供了访问图书馆中包含的各个突变细胞克隆的方法。 本发明包括描述的库，制作方法和用于构建库的向量。 还提供了通过序列或汇总和筛选来访问图书馆的各个部分的方法。 本发明还提供了从文库细胞分离和产生的特异性基因突变的非人转基因动物的产生。

公开(公告)号：US20040066084A1

公开(公告)日：2004-04-08

申请号：US10470932

申请日：2003-07-31

Inventor： Claudio Bernoni

IPC: B60B007/01

CPC classification number: B60B7/01

Abstract: The invention relates to a wheel (1) comprising a rim (2), a disc (3), a protective ring (4) with an outer surface (4a) and an inner surface (4b), and means (5) for fixing the ring (4) to the rim (2). To facilitate separation of the ring (4) from the rim (2), the protective ring (4) can be accessed from the inner surface (4b) through holes (8) made in the lip (2a) of the rim (2).

Abstract translation: 本发明涉及一种包括轮辋（2），盘（3），具有外表面（4a）和内表面（4b）的保护环（4）的轮（1）和用于固定的装置（5） 环（4）到边缘（2）。 为了便于环（4）与轮缘（2）的分离，保护环（4）可以通过形成在轮辋（2）的唇缘（2a）中的孔（8）从内表面（4b）进入， 。