公开(公告)号：US20040116730A1

公开(公告)日：2004-06-17

申请号：US10667782

申请日：2003-09-23

Applicant: BASF Aktiengesellschaft

Inventor： Volker Schliephake ,  Ulrich Hammon ,  Ernst Lang ,  Carl-Ludwig Kruger ,  Jurgen Schroder ,  Klaus Joachim Muller-Engel

IPC: C07C051/235 ,  C07C051/16 ,  C07C253/26

CPC classification number: C07C253/26 ,  C07C51/252 ,  C07C57/04 ,  C07C255/08

Abstract: Organic compounds are prepared by heterogeneously catalyzed partial gas-phase oxidation of precursor compounds by a process in which a portion of the reaction gas starting mixture is brought from a low initial pressure to a higher final pressure by means of a radial compressor.

Abstract translation: 通过使反应气体起始混合物的一部分通过径向压缩机从低初始压力升至较高的最终压力的方法，通过异构催化的前体化​​合物的部分气相氧化来制备有机化合物。

公开(公告)号：US20030100793A1

公开(公告)日：2003-05-29

申请号：US10204286

申请日：2002-09-10

Inventor： Helmut Springer ,  Peter Heymanns

IPC: C07C051/235

CPC classification number: C07C51/235 ,  Y02P20/582 ,  C07C53/126

Abstract: The invention relates to a method for producing aliphatic carboxylic acids from aldehydes by means of oxidation with oxygen or gases containing oxygen. This novel process is carried out in at least two stages at different temperatures, preferably in the absence of catalysts.

Abstract translation: 本发明涉及通过氧气或含氧气体从醛制备脂族羧酸的方法。 该新方法在不同温度下进行至少两个阶段，优选在不存在催化剂的情况下进行。

公开(公告)号：US20020038051A1

公开(公告)日：2002-03-28

申请号：US09783387

申请日：2001-02-15

Applicant: Degussa-Huls AG

Inventor： Daniel Ostgard ,  Jorg Sauer ,  Andreas Freund ,  Monika Berweiler ,  Matthias Hopp ,  Rudolf Vanheertum ,  Walther Girke

IPC: C07C051/235 ,  C07C045/29

CPC classification number: C07C229/16 ,  B01J23/8472 ,  B01J23/868 ,  B01J23/8926 ,  B01J25/00 ,  C07C51/295 ,  C07C227/02 ,  C07C59/06 ,  C07C55/07

Abstract: Raney copper which is doped with at least one metal from the group comprising iron and/or noble metals is used as a catalyst in the dehydrogenation of alcohols.

Abstract translation: 在由醇和/或贵金属组成的组中掺杂有至少一种金属的阮内铜用作醇脱氢中的催化剂。

公开(公告)号：US20020016503A1

公开(公告)日：2002-02-07

申请号：US09746186

申请日：2000-12-21

Inventor： Mark A. Leiber ,  Jerry R. Ebner ,  Kam-To Wan ,  Anthony Woods ,  Peter Rogers

IPC: C07C051/235

CPC classification number: B01J23/56 ,  B01J21/18 ,  B01J37/0205 ,  C07F9/3813

Abstract: This invention relates to the use of a supplemental promoter in conjunction with a noble-metal-containing catalyst comprising a carbon support in catalyzing liquid phase oxidation reactions, a process for making of an improved catalyst comprising such a supplemental promoter, and an improved catalyst comprising such a supplemental promoter. In a particularly preferred embodiment, a supplemental promoter (most preferably bismuth or tellurium) is used in conjunction with a noble-metal-containing catalyst comprising a carbon support in a liquid phase oxidation process wherein N-(phosphonomethyl)iminodiacetic acid (i.e., nullPMIDAnull) or a salt thereof is oxidized to form N-(phosphonomethyl)glycine (i.e., nullglyphosatenull) or a salt thereof. The benefits of such a process include increased oxidation of the formaldehyde and formic acid by-products, and, consequently, decreased final concentrations of those by-products as well as other undesirable by-products, most notably N-methyl-N-(phosphonomethyl)glycine (i.e., nullNMGnull).

Abstract translation: 本发明涉及补充促进剂与包含碳载体催化液相氧化反应的含贵金属的催化剂的使用，制备包含这种补充促进剂的改进的催化剂的方法，以及改进的催化剂，包括 这样的补充推动者。 在特别优选的实施方案中，补充促进剂（最优选铋或碲）与液相氧化方法中含有碳载体的含贵金属的催化剂结合使用，其中N-（膦酰基甲基）亚氨基二乙酸（即“ PMIDA“）或其盐被氧化形成N-（膦酰基甲基）甘氨酸（即”草甘膦“）或其盐。 这种方法的好处包括增加甲醛和甲酸副产物的氧化，从而减少那些副产物以及其它不希望的副产物的最终浓度，特别是N-甲基-N-（膦酰甲基 ）甘氨酸（即“NMG”）。

公开(公告)号：US20010021788A1

公开(公告)日：2001-09-13

申请号：US09800705

申请日：2001-03-07

Inventor： Yukihiro Matsumoto ,  Takeshi Nishimura ,  Kazuhiko Sakamoto ,  Hidefumi Haramaki

IPC: C07C409/44 ,  C07C051/16 ,  C07C051/235

CPC classification number: C07C51/252 ,  C07C51/46 ,  C07C57/04

Abstract: In a method for producing acrylic acid by the steps of a reaction of catalytic gas phase oxidation, absorbing the acrylic acid with an absorbent, and dehydrating the acrylic acid-containing aqueous solution, the method is characterized that the step of dehydration comprises adding and an azeotropic solvent, distilling the resultant mixture, and adjusting the acrylic acid concentration at the top of the column in the range of 0.06-0.80 wt. %, thereby preventing the bottoms of the azeotropic dehydration column from substantially containing the azeotropic solvent and water. As results, the acrylic acid is kept from forming a polymer in any of the distillation columns involved in the production, and effective utilization of acrylic acid.

Abstract translation: 在通过催化气相氧化反应，吸收丙烯酸和吸收剂的步骤和使含丙烯酸水溶液脱水的步骤来制备丙烯酸的方法中，脱水步骤包括加入和 共沸溶剂，蒸馏得到的混合物，并调节柱顶部的丙烯酸浓度为0.06-0.80wt。 ％，从而防止共沸脱水塔的底部基本上含有共沸溶剂和水。 结果，丙烯酸在生产中涉及的任何蒸馏塔中都不会形成聚合物，有效利用丙烯酸。

公开(公告)号：US20010005762A1

公开(公告)日：2001-06-28

申请号：US09748924

申请日：2000-12-27

Inventor： Tetsuya Shintaku ,  Masahide Tanaka ,  Nobushige Itaya

IPC: C07C205/00 ,  C07C207/00 ,  C07C051/16 ,  C07C051/235

CPC classification number: C07C201/16 ,  C07C205/51 ,  C07C205/53

Abstract: The present invention provides a method of producing easily and in a high yield a threo-2-hydroxy-3-nitrobutanoic acid compound or a mixture of a threo- and an erythro-2-hydroxy-3-nitrobutanoic acid compounds, this mixture having an erythro compound:threo compound ratio of about 1:1, which method includes reacting, in a solvent, a 2-hydroxy-3-nitrobutanoic acid compound having the formula (I) 1 wherein R is optionally substituted alkyl or optionally substituted aryl, with not less than 1 equivalent of a base to isomerize (i) the erythro compound into the threo compound, or (ii) the threo compound into the erythro compound, and a method for separating the erythro and the threo compounds easily and in a high yield. The separation method includes reacting the mixture of threo- and erythro-compounds with not more than 1 equivalent of potassium carbonate per threo compound in a solvent. According to the method of the present invention, useful pharmaceuticals can be produced easily in a high yield.

Abstract translation: 本发明提供了一种容易且高产率地制备苏-22-羟基-3-硝基丁酸化合物或苏 - 和 - 赤-2-羟基-3-硝基丁酸化合物的混合物的方法，该混合物具有 红霉素化合物：苏化合物比例为约1:1，该方法包括在溶剂中使具有式（I）的2-羟基-3-硝基丁酸化合物（其中R是任选取代的烷基或任选取代的芳基）与 不少于1当量的碱，将（i）赤式化合物异构化为苏化合物，或（ii）苏化合物进入赤式化合物，以及容易且高收率地分离赤式和苏式化合物的方法 。 分离方法包括在溶剂中使苏氨酸和赤式化合物的混合物与不多于1当量的碳酸钾/苏化合物反应。 根据本发明的方法，可以容易地以高产率制备有用的药物。

公开(公告)号：US20040192964A1

公开(公告)日：2004-09-30

申请号：US10784825

申请日：2004-02-24

Applicant: BASF Aktiengesellschaft

Inventor： Jochen Petzoldt ,  Martin Dieterle ,  Heiko Arnold ,  Wilhelm Ruppel ,  Klaus Joachim Muller-Engel

IPC: C07C051/235

CPC classification number: C07C45/35 ,  C07C51/252 ,  C07C47/22 ,  C07C57/04

Abstract: In a process for heterogeneously catalyzed partial gas phase oxidation of propene to acrolein, the starting reaction gas mixture is oxidized over a fixed catalyst bed which consists of at least two fixed catalyst bed zones and is accommodated in two successive temperature zones A, B, and the transition from temperature zone A to temperature zone B does not spatially coincide with a transition from one fixed catalyst bed zone to another fixed catalyst bed zone.

Abstract translation: 在将丙烯非均相催化的部分气相氧化成丙烯醛的过程中，起始反应气体混合物在由至少两个固定的催化剂床区组成的固定催化剂床上被氧化，并被容纳在两个连续的温度区A，B和 从温度区A到温度区B的过渡在空间上与从一个固定的催化剂床区到另一个固定催化剂床区的过渡不一致。

公开(公告)号：US20040192963A1

公开(公告)日：2004-09-30

申请号：US10806460

申请日：2004-03-23

Applicant: BASF Aktiengesellschaft

Inventor： Martin Dieterle ,  Jochen Petzoldt ,  Klaus Joachim Muller-Engel ,  Heiko Arnold

IPC: C07C051/235

CPC classification number: C07C51/252 ,  C07C57/04

Abstract: In a process for partially oxidizing acrolein to acrylic acid in the gas phase under heterogeneous catalysis, the starting reaction gas mixture is oxidized at an acrolein loading of null145 and null70 l (STP) of acrolein/l of fixed catalyst bednullh over a fixed catalyst bed which is accommodated in two successive reaction zones A, B, the highest temperature of the reaction gas mixture within reaction zone A being above the highest temperature of the reaction gas mixture within reaction zone B.

Abstract translation: 在非均相催化下在气相中将丙烯醛部分氧化为丙烯酸的方法中，起始反应气体混合物以丙烯醛负载<= 145和> = 70l（STP）的丙烯醛/ l固定催化剂床进行氧化。 h在固定的催化剂床上，其被容纳在两个连续的反应区A，B中，反应区A内的反应气体混合物的最高温度高于反应区B内的反应气体混合物的最高温度。

公开(公告)号：US20040015013A1

公开(公告)日：2004-01-22

申请号：US10460153

申请日：2003-06-13

Applicant: BASF Aktiengesellschaft

Inventor： Ulrich Hammon ,  Jochen Petzoldt ,  Klaus Joachim Mueller-Engel ,  Martin Dieterle

IPC: C07C051/16 ,  C07C051/235

CPC classification number: C07C51/252 ,  B01J8/003 ,  B01J8/008 ,  B01J8/067 ,  B01J23/002 ,  B01J2208/00707 ,  B01J2208/00752 ,  B01J2208/00761 ,  B01J2523/00 ,  C07C51/215 ,  C07C57/04 ,  B01J2523/12 ,  B01J2523/13

Abstract: A process for the heterogeneously catalyzed gas-phase partial oxidation of an organic compound over a fixed catalyst bed present in a fixed-bed reactor having a plurality of catalyst tubes, in which the reduction of the quality of the catalyst load with increasing duration of operation is restored by a partial catalyst change, is described.

Abstract translation: 存在于具有多个催化剂管的固定床反应器中的固定催化剂床上的有机化合物的非均相催化气相部分氧化的方法，其中随着操作持续时间的延长，催化剂负载的质量降低 被部分催化剂改变所恢复。

公开(公告)号：US20040015012A1

公开(公告)日：2004-01-22

申请号：US10459782

申请日：2003-06-12

Applicant: BASF Aktiengesellschaft

Inventor： Ulrich Hammon ,  Jochen Meschke ,  Ulrich Rauh ,  Klaus Joachim Muller-Engel ,  Peter Schlemmer

IPC: G06F019/00 ,  G01N031/00 ,  C07C051/16 ,  C07C051/235

CPC classification number: C07C51/215 ,  C07C45/33 ,  C07C45/34 ,  C07C45/35 ,  C07C51/252 ,  C07C47/22 ,  C07C57/04

Abstract: A continuously operated heterogeneously catalyzed gas-phase partial oxidation of at least one organic compound in an oxidation reactor is operated safely by a process in which an explosion diagram for the feed gas mixture is deposited as the basis of a cut-out mechanism in a computer.

Abstract translation: 在氧化反应器中连续操作的至少一种有机化合物的气相部分氧化被安全地通过其中沉积原料气体混合物的爆炸图作为计算机中的切断机构的基础的方法来操作 。