利索-全球专利检索

  1. 登录
  2. 注册

搜索结果

181 条记录 (耗时 0.023 秒)

    Preparation of oxydicarboxylic acid salts
    6.
    发明授权
    Preparation of oxydicarboxylic acid salts 失效
    氧基二羧酸盐的制备

    公开(公告)号：US4110371A

    公开(公告)日：1978-08-29

    申请号：US806981

    申请日：1977-06-16

    申请人： Heinz Schulze ,  Edward T. Marquis

    发明人： Heinz Schulze ,  Edward T. Marquis

    IPC分类号： C07C51/295 ,  C07C59/305 ,  C07C59/12

    CPC分类号： C07C59/305 ,  C07C51/295

    摘要： Oxyethylene dicarboxylic acid alkali metal salts are prepared from the corresponding oxydiethylene or polyoxyethylene diol and an aqueous alkali metal hydroxide in the presence of a catalytically effective amount of a nickel-copper-chromia catalyst at temperatures from about 200 to 300.degree. C. and pressures sufficient to maintain the reactants and products substantially in liquid phase. Preferably, the disodium salt of oxydiacetic acid is prepared by the oxidation of diethylene glycol with an aqueous sodium hydroxide solution in the presence of a catalytically effective amount of the nickel-copper-chromia catalyst. The disodium oxydiacetate can be readily precipitated from the crude reaction mixture by addition of a mixture of methoanol-isopropanol with subsequent filtration.

    摘要翻译： 氧化乙烯二羧酸碱金属盐由相应的氧化二乙烯或聚氧乙烯二醇和碱金属氢氧化物水溶液在催化有效量的镍 - 铜 - 氧化铬催化剂的存在下，在约200至300℃的温度和足够的压力下制备 以使反应物和产物保持基本上处于液相。 优选地，氧化二乙酸的二钠盐通过在催化有效量的镍 - 铜 - 氧化铬催化剂存在下，用氢氧化钠水溶液氧化二甘醇来制备。 通过加入甲醇 - 异丙醇的混合物随后过滤，氧化二乙酸二钠可以从粗反应混合物中容易地沉淀。

    Method for preparing pentachloroacetone and dichloroacetic acid from isopropyl ethers
    7.
    发明授权
    Method for preparing pentachloroacetone and dichloroacetic acid from isopropyl ethers 失效
    从异丙醚制备五氯丙酮和二氯乙酸的方法

    公开(公告)号：US3996272A

    公开(公告)日：1976-12-07

    申请号：US511842

    申请日：1974-10-03

    申请人： Joanne D. Burger ,  William L. Howard

    发明人： Joanne D. Burger ,  William L. Howard

    IPC分类号： C07C45/51 ,  C07C51/00 ,  C07C51/295 ,  C07C53/16 ,  C07C49/08

    CPC分类号： C07C51/00 ,  C07C45/513 ,  C07C51/295

    摘要： This invention relates to a chemical process for preparing pentachloro-2-propanone (pentachloroacetone) and dichloroacetic acid from isopropyl ethers which may be partially chlorinated. The pentachloroacetone process is carried out by reacting the isopropyl ethers with chlorine in the presence of water to produce pentachloroacetone which can then be recovered. Alternatively, if dichloroacetic acid is desired, the pentachloroacetone process may be carried further by reacting the pentachloroacetone with a base-acting material to produce a salt of dichloroacetic acid and then reacting this salt with acid to produce dichloroacetic acid of about 95% purity.

    摘要翻译： 本发明涉及可以部分氯化的异丙醚制备五氯-2-丙酮（五氯丙酮）和二氯乙酸的化学方法。 五氯丙酮方法是通过在水存在下使异丙醚与氯反应，生成五氯丙酮，然后将其回收。 或者，如果需要二氯乙酸，则五氯丙酮方法可以进一步通过使五氯丙酮与碱作用物质反应以制备二氯乙酸的盐，然后使该盐与酸反应，产生约95％纯度的二氯乙酸。

    Reactions involving carbon tetrahalides and .alpha.-methyl ketones or ketones having .alpha.,.alpha.'-hydrogens
    8.
    发明授权
    Reactions involving carbon tetrahalides and .alpha.-methyl ketones or ketones having .alpha.,.alpha.'-hydrogens 失效
    涉及四卤化碳和{60-甲基酮或酮的反应，其具有{60，{60-

    公开(公告)号：US3953494A

    公开(公告)日：1976-04-27

    申请号：US98078

    申请日：1970-12-14

    申请人： Cal Yale Meyers ,  Walter Sidney Matthews, III

    发明人： Cal Yale Meyers ,  Walter Sidney Matthews, III

    IPC分类号： C07C45/63 ,  C07C51/00 ,  C07C51/295 ,  C07C51/28 ,  C07C67/42

    CPC分类号： C07C251/72 ,  C07C45/63 ,  C07C51/00 ,  C07C51/295

    摘要： A process for preparing aldehydes, ketones, carboxylic acids and esters by reaction of various substrates with carbon tetrahalides in the presence of a strong base. The reactions are accelerated by the presence of a polar solvent. Anions of the substrate attack the carbon tetrahalide to produce a halogenated intermediate and a dihalocarbene. The halogenated intermediate reacts with the base to form the indicated products. By the reactions of this process, primary alcohols are converted to aldehydes, carboxylic acids and esters, secondary alcohols are converted to ketones and ketones having an .alpha.-methyl group or both .alpha. and .alpha.' hydrogens are converted to carboxylic acids and esters. Non .alpha.-methyl ketones having .alpha. but no .alpha.' hydrogens are simply .alpha.-halogenated. The dihalocarbene generated in the reaction may attack the product, solvent, or another substrate to form other products.

    摘要翻译： 在强碱存在下，通过各种底物与四卤化碳反应来制备醛，酮，羧酸和酯的方法。 通过极性溶剂的存在来加速反应。 底物的阴离子侵蚀四卤化碳以产生卤化中间体和二卤代碳烯。 卤化中间体与碱反应形成指定的产物。 通过该方法的反应，将伯醇转化成醛，羧酸和酯，将仲醇转化成酮，将具有α-甲基或α和α'氢的酮转化为羧酸和酯。 具有α但不含α'氢的非α-甲基酮仅仅是α-卤代的。 在反应中产生的二卤代碳烯可能会侵蚀产物，溶剂或另一种底物以形成其它产物。

    Tricyclic amines and processes for the preparation thereof
    9.
    发明授权
    Tricyclic amines and processes for the preparation thereof 失效
    三环胺及其制备方法

    公开(公告)号：US3884967A

    公开(公告)日：1975-05-20

    申请号：US44940574

    申请日：1974-03-08

    申请人： HOFFMANN LA ROCHE

    发明人： KYBURZ EMILIO ,  SPIEGELBERG HANS

    IPC分类号： C07C51/16 ,  C07C51/295 ,  C07C63/72 ,  C07C63/74 ,  C07C119/00

    CPC分类号： C07C63/74 ,  C07C51/16 ,  C07C51/295 ,  C07C63/72 ,  C07C65/105

    摘要： 1-Chloro- or 1-fluoro- derivatives of 5H-dibenzo(a, d)cycloheptenes and 1-chloro- or 1-fluoro- derivatives of 10,11dihydr-5H-dibenzo(a,d)cycloheptenes having, at position 5, a basic exocyclic side chain of the formula

    WHEREIN R1 is hydrogen or methyl, AND INTERMEDIATES THEREFOR ARE PREPARED BY ALTERNATE PROCEDURES. The described end-products are useful, for example, as psychopharmacological antidepressants.

    摘要翻译： 1,5-二苯并[a，d]环庚烯的1-氯 - 或1-氟 - 衍生物和10,11-二氢-5H-二苯并[a，d]环庚烯的1-氯 - 或1-氟 - 衍生物，其具有 位置5，式WHEREIN R1是氢或甲基的基本环外侧链，以及其通过替代程序制备的中间体。 所描述的最终产品是有用的，例如作为精神药物抗抑郁药。

    Synthesis of zearalanone and related compounds
    10.
    发明授权
    Synthesis of zearalanone and related compounds 失效
    ZEARARANONE及相关化合物的合成

    公开(公告)号：US3852307A

    公开(公告)日：1974-12-03

    申请号：US24734372

    申请日：1972-04-25

    申请人： COMMERCIAL SOLVENTS CORP

    发明人： URRY W ,  MULLENBACH G

    IPC分类号： C07C51/295 ,  C07C57/03 ,  C07C57/66 ,  C07D313/00 ,  C07D317/30 ,  C07D9/00 ,  C07D7/20

    CPC分类号： C07C403/16 ,  C07C51/295 ,  C07C57/03 ,  C07C57/66 ,  C07C2601/14 ,  C07D313/00 ,  C07D317/30 ,  C07C59/76

    摘要： WHEREIN X is an integer having a value from 0 to 6 inclusive and Y is an integer having a value from 3 to 8 inclusive. It also provides for new methods of making compounds useful in the synthesis of zearalanone and related compounds. The compounds 6-acetoxyhexanoic acid; 2-(5-hexenoyl)cyclohexanone; 7-keto-11-dodecenoic acid; 2-hydroxyethyl 7-keto11-dodecenoate ethylene ketal; N,N-dimethyl 7-keto-11dodecenamide ethylene ketal; 7-keto-11-dodecenal ethylene ketal; 9-keto-2,13-tetradecadienic acid ethylene ketal; 2-hydroxyethyl 9-keto-2,13-tetradecadienoate ethylene ketal; the sodium salt of ethyl 6-(6-keto-10-undecenyl)- Beta -dihydroresorcylate ethylene ketal; ethyl 3-bromo-6-(6-keto-10-undecenyl)- Beta dihydroresorcylate ethylene ketal; ethyl 6-(6-keto-10-undecenyl)Beta -resorcylate ehtylene ketal; ethyl 6-(6-keto-10-undecenyl)Beta -resorcylate ethylene ketal dibenzyl ether; ethyl 6-(6keto-10-hydroxyundecyl)- Beta -resorcylate ethylene ketal dibenzyl ether; and 6-(10-hydroxy-6-keto-undecyl)- Beta resorcylic acid dibenzyl ether are disclosed. Methods for preparing these compounds are also disclosed.

    This invention provides a new synthesis for zearalanone and for related compounds having more or fewer carbon atoms in the nonaromatic ring than does zearalanone, which related compounds and zearalanone are represented by the formula

    摘要翻译： 本发明提供了一种新的Zearalanone合成物，以及在非芳族环中具有或多于少于碳原子的相关化合物的合成相对于Zearalanone，该相关化合物和泽西拉酮由式WHEREIN X表示为0至6的整数 Y为包含3〜8的整数。 它还提供了制备化合物的新方法，可用于合成泽西拉酮及其相关化合物。