Creatinol sulfate and synthesis method thereof
    1.
    发明申请
    Creatinol sulfate and synthesis method thereof 审中-公开
    硫酸肌酐及其合成方法

    公开(公告)号:US20110105797A1

    公开(公告)日:2011-05-05

    申请号:US12590139

    申请日:2009-11-02

    IPC分类号: C07C277/02

    CPC分类号: C07C277/08 C07C279/08

    摘要: A chemical compound of creatinol sulfate is formed by chemically reacting N-methyl-amino-ethanol, cyanamide, with sulfuric acid to produce the creatinol sulfate with relatively higher yield rate and purity, wherein the mol ratio of N-methyl-amino-ethanol, sulfuric acid, and cyanamide is approximately 2:1:2.

    摘要翻译: 通过N-甲基 - 氨基 - 乙醇,氨基氰与硫酸的化学反应形成硫酸肌酸酐化合物,以相对较高的收率和纯度生产硫酸肌酐,其中N-甲基 - 氨基 - 乙醇, 硫酸和氰胺约为2:1:2。

    Antihypertensive pyridylguanidine compounds
    7.
    再颁专利
    Antihypertensive pyridylguanidine compounds 失效
    抗高血压吡啶胍化合物

    公开(公告)号:USRE31244E

    公开(公告)日:1983-05-17

    申请号:US314023

    申请日:1981-10-22

    申请人: Hans J. Petersen

    发明人: Hans J. Petersen

    摘要: The invention relates to a series of new compounds, to methods for preparing the compounds, to compositions containing said compounds which are useful in the human and veterinary medical practice, and to methods for treating patients suffering from certain illnesses with said compounds, the new compounds having the general formula I ##STR1## or the tautomeric forms thereof in which the R.sup.1 -substituted cyano-guanidyl radical is placed in the 2-, 3- or 4-position of the pyridine ring, and in which R.sup.1 stands for a straight or branched, saturated or unsaturated, aliphatic hydrocarbon radical having from 1 to 8 carbon atoms, a cycloalkyl or cycloalkenyl radical having from 3 to 7 carbon atoms, an aryl or an aralkyl radical, and R.sup.2 stands for hydrogen, halogen, hydroxy, lower alkyl or alkoxy radicals; and in the case of the present compounds containing one or more asymmetric carbon atoms, also the stereoisomers thereof and racemic mixtures of same; and salts of the compounds of formula I with nontoxic, pharmaceutically acceptable acids. The new compounds of the invention have surprisingly shown to be highly potent hypotensive compounds giving rise to a pronounced reduction of the blood pressure. They have a low toxicity and consequently a high therapeutic ratio.

    INTEGRATED SYNTHESIS OF COMMODITY CHEMICALS FROM WASTE PLASTIC

    公开(公告)号:US20200325021A1

    公开(公告)日:2020-10-15

    申请号:US16834720

    申请日:2020-03-30

    摘要: A process to extract carbon from hydrophobic waste comprises: combining the hydrophobic waste with an oxide of an active metal to form a storable, moisture-resistant feedstock for high-temperature processing; heating the feedstock in a furnace to yield an effluent gas entraining a carbide of the active metal; cooling the effluent gas entraining the carbide of the active metal; introducing nitrogen into the cooled effluent gas entraining the carbide of the active metal, to yield a cyanamide of the active metal and elemental carbon; and acidically hydrolyzing the cyanamide of the active metal to yield a cyanamide compound and a salt of the active metal.