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公开(公告)号:US4484993A
公开(公告)日:1984-11-27
申请号:US416493
申请日:1982-09-10
申请人: Nobuo Ishikawa , Tomoya Kitazume
发明人: Nobuo Ishikawa , Tomoya Kitazume
IPC分类号: B01J19/10 , C07C17/26 , C07C29/40 , C07C33/20 , C07C45/00 , C07C45/45 , C07C45/67 , C07C45/77 , C07C47/277 , C07C49/167 , C07C49/175 , C07C49/255 , C07C49/333 , C07C49/92 , C07C51/04 , C07C51/487 , C07C51/58 , C07C51/60 , C07C59/135 , C07F3/06
CPC分类号: C07F3/06 , B01J19/10 , C07C17/269 , C07C29/40 , C07C33/20 , C07C45/004 , C07C45/45 , C07C45/673 , C07C45/77 , C07C47/277 , C07C49/167 , C07C49/175 , C07C49/255 , C07C49/333 , C07C49/92 , C07C51/04 , C07C51/487 , C07C51/58 , C07C51/60 , C07C59/135
摘要: A process for producing fluorine-containing organic compounds characterized in that fluorine-containing aliphatic iodides which comprise at least one selected from the group of R.sub.f I, R.sub.f ZnI and R.sub.f SnX.sub.2 I (where R.sub.f indicates a fluorine-containing aliphatic group; and X indicates halogen), or which comprise R.sub.f COOR' (where R.sub.f indicates a fluorine-containing aliphatic group; and R' indicates an aliphatic hydrocarbon group or aromatic hydrocarbon group) are reacted with organic compounds under ultrasonic wave action, whereby the R.sub.f group or the R.sub.f CO group is introduced into the said organic compounds.
摘要翻译: 一种制备含氟有机化合物的方法,其特征在于含有选自RfI,RfZnI和RfSnX2I(其中Rf表示含氟脂族基团,X表示卤素)中的至少一种的含氟脂族碘化物,或 其中RfCOOR'(其中Rf表示含氟脂族基团,R'表示脂族烃基或芳香族烃基)与有机化合物在超声波作用下反应,由此将Rf基团或RfCO基团引入 所述有机化合物。
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公开(公告)号:US20120252815A1
公开(公告)日:2012-10-04
申请号:US13516370
申请日:2010-11-18
申请人: Frank Stieber , Dirk Wienke
发明人: Frank Stieber , Dirk Wienke
IPC分类号: A61K31/454 , A61K31/496 , C07D417/14 , A61K31/4545 , A61K31/5377 , C07D221/20 , A61K31/438 , C07C49/333 , A61P35/00 , A61P9/10 , A61P27/02 , A61P29/00 , A61P19/02 , A61P25/28 , A61P9/00 , A61P17/02 , A61P37/06 , C07D417/04
CPC分类号: C07D249/06 , C07D263/32 , C07D277/28 , C07D277/40 , C07D417/04 , C07D417/14
摘要: The present invention relates to compounds of the formula (I), in which R1, R2, R3, R4, R5, R6, R7, R8, R9, R10, R11, R12, R13, R14, R15, R16, R17, M1, M2, M3, Y1, Y2, V, W, n, m and o have the gleanings given herein, and physiologically acceptable salts, derivatives, prodrugs, solvates, tautomers and stereoisomers thereof, including mixtures thereof in all ratios, for use in the treatment of diseases which are influenced by inhibition of Sph kinase 1.
摘要翻译: 本发明涉及式(I)化合物,其中R1,R2,R3,R4,R5,R6,R7,R8,R9,R10,R11,R12,R13,R14,R15,R16,R17,M1 ,M2,M3,Y1,Y2,V,W,n,m和o具有本文给出的收集,以及生理上可接受的盐,衍生物,前药,溶剂合物,互变异构体和立体异构体,包括其所有比例的混合物, 受Sph激酶1抑制影响的疾病的治疗。
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公开(公告)号:US5262085A
公开(公告)日:1993-11-16
申请号:US732524
申请日:1991-07-19
IPC分类号: C07C49/327 , C07C43/225 , C07C45/00 , C07C45/30 , C07C45/46 , C07C49/333 , C07C49/35 , C07C49/567 , C07C49/813 , C07C49/84 , C07C69/017 , C07C69/76 , C07C255/13 , C07C255/54 , C07C255/56 , C07C323/03 , C07C323/07 , C07C323/16 , C07C323/60 , C09K19/12 , C09K19/14 , C09K19/20 , C09K19/28 , C09K19/30 , C09K19/32 , C09K19/34 , C09K19/42 , G02F1/13 , C07C19/08 , C07D211/72
CPC分类号: C09K19/3087 , C07C255/13 , C07C255/54 , C07C255/56 , C07C323/03 , C07C323/07 , C07C323/16 , C07C323/60 , C07C43/225 , C07C45/00 , C07C45/305 , C07C45/46 , C07C49/333 , C07C49/567 , C07C49/813 , C07C49/84 , C07C69/017 , C09K19/12 , C09K19/14 , C09K19/20 , C09K19/28 , C09K19/3003 , C09K19/3028 , C09K19/3066 , C09K19/3068 , C07C2101/14
摘要: Trifluoromethylene compounds of the formula I ##STR1## which can be used as components of liquid-crystalline media for liquid-crystal and electrooptical display elements.
摘要翻译: 可用作液晶和电光显示元件的液晶介质的组分的式I的三氟亚甲基化合物。
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