Pyrazoline compounds
    5.
    发明授权
    Pyrazoline compounds 失效
    吡咯啉化合物

    公开(公告)号:US3849406A

    公开(公告)日:1974-11-19

    申请号:US29393172

    申请日:1972-10-02

    申请人: SANDOZ LTD

    CPC分类号: C07D231/06

    摘要: 1. A COMPOUND OF THE FORMULA

    (R7-(R8,R9-PHENYLENE)-(5-R6-2-PYRAZOLIDIN-3,1-YLENE)-

    (R4,R5-1,4-PHENYLENE)-SO2-A1-CO-X-A2-N(-R2)(-R3)-

    (-R)(N-1))(N-1)(+) ANION(-)(N-1)

    WHEREIN A1 AND A2, INDEPENDENTLY, ARE ALKYLENE OF 1 TO 3 CARBON ATOMS, X IS -O- OR

    >N-R10

    WHEREIN R10 IS HYDROGEN OR LOWER ALKYL, R1 IS HYDROGEN OR SUBSTITUTED OR UNSUBSTITUTED ALKYL, R2 IS SUBSTITUTED OR UNSUBSTITUTED ALKYL, CYCLOHEXYL, METHYLCYCLOHEXYL, OR SUBSTITUTED OR UNSUBSTITUTED PHENYL, OR WHEN X SIGNIFIES

    >N-R10

    R2 AND R10 TOGETHER WITH A2 AND THE TWO ATTACHED NITROGENS FORM A PIPERAZINE RING, R3 IS SUBSTITUTED OR UNSUBSTITUTED ALKYL, OR R2 AND R5 TOGETHER WITH THE NITROGEN ATOM FORM A PIPERIDINE OR MORPHOLINE RING, R4 AND R5 ARE, INDEPENDENTLY, HYDROGEN, HALOGEN, SUBSTITUTED OR UNSUBSTITUTED ALKYL, OR ALKOXY, R6 IS HYDROGEN, SUBSTITUTED OR UNSUBSTITUTED ALKYL OR SUBSTITUTED OR UNSUBSTITUTED PHENYL, R7, R8 AND R9 ARE, INDEPENDENTLY, HYDROGEN; HALOGEN; SUBSTITUTED OR UNSUBSTITUTED ALKYL, ALKYLSULPHONYL, ALKYLTHIO, OR PHENYL; ALKOXY; CYANO; CARBOXYLIC OR SULPONIC ACID AMIDE OR ESTER; OR ACYLAMINO; N IS 1 OR 2, AND ANION $ SIGNIFIES AN EQUIVALENT OF A NON-CHROMOPHORIC ANION PROVIDED THAT IN THE FOREGOING DEFINITIONS ANY ALKYL MOIETY CONTAINS 1 TO 8 CARBON ATOMS UNLESS OTHERWISE SPECIFIED; ANY SUBSTITUENT ON SUBSTITUTED ALKYL OR ON THE ALKYL MOIETY OF ALKYLTHIO OR ALKYLSULPHONYL IS HALOGEN, PHENYL, PHENOXY, ALKOXY OR 1 TO 4 CARBON ATOMS, HYDROXYL OR CYANO, ANY SUBSTITUENT ON SUBSTITUTED PHENYL IS METHYL, CHLORO, OR METHOXY; ANY CARBOXYLIC OR SULPHONIC ACID ESTER IS AN ALKYL ESTER WHEREIN THE ALKYL GROUP CONTAINS 1 TO 5 CARBON ATOMS; ANY ACYL PORTON OF AN ACYLAMINO GROUP IS ALKONYL OF 1 TO 8 CARBON ATOMS OR ALKOXYCARBONYL OF 2 YO 9 CARBON ATOMS; BENZOYL; CHLORO- OR METHYLBENZOLY; PHENYLSULPHONYL, METHYLPHENYLSULPHONYL; METHYLSULPHONYL; OR ETHYLSULPHONYL, AND ANY HALOGEN IS CHLORO OR FLUORO.

    2-pyrazoline-1-carboxamide sulfonamide derivatives
    6.
    发明授权
    2-pyrazoline-1-carboxamide sulfonamide derivatives 失效
    2-吡咯烷-1-羧酰胺磺酰胺衍生物

    公开(公告)号:US3780058A

    公开(公告)日:1973-12-18

    申请号:US3780058D

    申请日:1971-09-16

    IPC分类号: C07D231/06 C07D49/10

    CPC分类号: C07D231/06 Y10S514/866

    摘要: 2-PYRAZOLINE-1-CARBOXAMIDE SULFONAMIDE DERIVATIVES HAVING THE GENERAL FORMULA:

    (3-R,4-R1,5-R2,5-R3-2-PYRAZOLIN-1-YL)-CO-NH-SO2-(1,4-

    PHENYLENE)-Z

    IN WHICH Z IS HYDROGEN, HALOGEN OR LOWER ALKYL, AND R, R1, R2, R3 ARE EACH HYDROGEN OR LOWER ALKYL. THESE SULFONAMIDE COMPOUNDS HAVE A HYPOGLYCEMIC EFFECT AND ARE OBTAINED BY REACTING A 2-PYRAZOLINE DERIVATIVES SUCH AS HN-CR2R3-CHR1-CR=N WITH AN ARYLSULFONYLUREA SUCH AS Z-C2H4EO2NHCONH2 OR WITH AN ARYLSULFONYLISOCYANATE SUCH AS Z-C6H4SO2NCO OR BY THE THERMAL DECOMPOSITION OF THE MOLECULAR COMBINATION OF THE 2PYRAZOLINE DERIVATIVE AND THE ARYSULFONYLUREA.

    Pyrazoline optical brightening agents
    9.
    发明授权
    Pyrazoline optical brightening agents 失效
    吡唑啉酮光亮剂

    公开(公告)号:US3852275A

    公开(公告)日:1974-12-03

    申请号:US20199371

    申请日:1971-11-24

    申请人: UGINE KUHLMANN

    IPC分类号: C07D231/06 C08K5/43 C07D49/10

    CPC分类号: C07D231/06 C08K5/43 C08L33/20

    摘要: The present invention provides compounds of the formula:

    WHEREIN Ar represents an aromatic residue which may be substituted by substituents not having a chromophoric or anionic character, R1 and R2 represent alkyl groups containing one to five carbon atoms, which may be the same or different, n is 2 or 3 and X represents a monovalent anion or its equivalent. It also relates to the preparation of such compounds and to their use in optical brightening or whitening fibres based on polymers or copolymers of acrylonitrile.

    摘要翻译: 本发明提供下式的化合物: