公开(公告)号：US20240294483A1

公开(公告)日：2024-09-05

申请号：US18572209

申请日：2022-06-22

申请人： BASF SE ,  Dow Global Technologies LLC

发明人： Andrei-Nicolae PARVULESCU ,  Joaquim Henrique TELES ,  Dominic RIEDEL ,  Dylan SEGERS ,  Massimo BERGAMO ,  Franciscus Johannes Robertus VAN NEER ,  Meinolf WEIDENBACH

IPC分类号： C07D301/12

CPC分类号： C07D301/12

摘要： The present invention relates in a first aspect to a process for the preparation of a liquid mixture comprising methanol, water and hydrogen peroxide, the process comprising: (i) providing a feed stream comprising methanol, and a feed stream comprising an aqueous hydrogen peroxide solution; (ii) combining the feed stream comprising the methanol and the feed stream comprising the aqueous hydrogen peroxide solution provided according to (i) at a point in time t1, so that a combined stream comprising methanol, hydrogen peroxide and water is obtained; (iii) filtrating the combined stream obtained according to (ii) at a point in time t2, through a filtration device, thereby obtaining a liquid mixture comprising methanol, hydrogen peroxide and water; wherein the period of time between t1 and t2 is at least 8 seconds. In a second aspect, the invention relates to the use of a liquid mixture obtained or obtainable from the process of the first aspect for the preparation of propylene oxide. A third aspect of the invention is directed to a method for the preparation of propylene oxide comprising: (i) providing a feed stream comprising methanol, a feed stream comprising an aqueous hydrogen peroxide solution and a feed stream comprising propylene; (ii) combining the feed stream comprising the methanol and the feed stream comprising the aqueous hydrogen peroxide solution provided according to (i) at a point in time t1, so that a combined stream comprising methanol, hydrogen peroxide and water is obtained; (iii) filtrating the combined stream obtained according to (ii) at a point in time t2, through a filtration device, thereby obtaining a liquid mixture comprising methanol, hydrogen peroxide and water; (iv) combining the feed stream comprising propylene either with the combined stream obtained in (ii) or with the liquid mixture obtained in (iii), thereby obtaining a liquid mixture comprising methanol, hydrogen peroxide, water and propylene; (v) bringing the liquid mixture obtained according to (iv) in an epoxidation zone in contact with an epoxidation catalyst comprising a zeolitic material having a framework structure comprising Si, O, and Ti under epoxidation reaction conditions, thereby obtaining in the epoxidation zone a mixture comprising propylene oxide, methanol and water; wherein the period of time between t1 and t2 are at least 8 seconds. In a fourth aspect, the invention relates to propylene oxide, obtained or obtainable from the method according to the third aspect.

公开(公告)号：US12030860B2

公开(公告)日：2024-07-09

申请号：US17264466

申请日：2019-06-11

申请人： KAO CORPORATION

发明人： Mee Lin Yap ,  Shingo Takada

IPC分类号： C07D301/12 ,  B01J31/34 ,  B01J37/00 ,  B01J37/04 ,  B01J37/08 ,  B01J37/30

CPC分类号： C07D301/12 ,  B01J31/34 ,  B01J37/0027 ,  B01J37/009 ,  B01J37/04 ,  B01J37/086 ,  B01J37/30 ,  B01J2231/72

摘要： The present invention provides: a method for producing an epoxyalkane capable of obtaining an epoxide in a high yield while attaining a high olefin conversion rate and a high selectivity for epoxides even when an olefin includes a long carbon chain, and a solid oxidation catalyst used in the method. The method for producing an epoxyalkane of the present invention comprises reacting an olefin with an oxidant in the presence of a solid oxidation catalyst, wherein the solid oxidation catalyst comprises a transition metal and a carrier that supports the transition metal, and the carrier is a metal oxide having a silyl group represented by the following general formula (1):

R1R2R3Si—  (1)



wherein R1, R2, and R3 are each independently a single bond, a hydrocarbon group, a halogenated hydrocarbon group, an alkoxy group, or a halogen, and at least one of R1, R2, and R3 is a hydrocarbon group having 3 or more carbon atoms or a halogenated hydrocarbon group having 3 or more carbon atoms.

公开(公告)号：US11492336B2

公开(公告)日：2022-11-08

申请号：US17264136

申请日：2019-06-11

申请人： KAO CORPORATION

发明人： Mee Lin Yap ,  Shingo Takada

IPC分类号： C07D301/12 ,  B01J23/30 ,  B01J27/16

摘要： The present invention provides: a method for producing an epoxyalkane capable of obtaining an epoxide in a high yield while attaining a high olefin conversion rate and a high selectivity for epoxides even when an olefin includes a long carbon chain, and a solid oxidation catalyst. The method for producing an epoxyalkane of the present invention comprises reacting an olefin with an oxidant in the presence of a solid oxidation catalyst, wherein the solid oxidation catalyst comprises a transition metal and a carrier that supports the transition metal, and the carrier is a composite of a metal oxide with a phosphonic acid.

公开(公告)号：US20220010443A1

公开(公告)日：2022-01-13

申请号：US17292612

申请日：2019-11-12

申请人： Condias GmbH ,  Johannes Gutenberg-Universität Mainz

发明人： Siegfried WALDVOGEL ,  Michael ZIRBES ,  Rieke NEUBER ,  Thorsten MATTHÉE

IPC分类号： C25B15/08 ,  C25B1/30 ,  C25B9/17 ,  C25B9/67 ,  C25B15/021 ,  C25B11/052 ,  C25B11/091 ,  C25B11/059 ,  C25B11/061 ,  C25B11/065 ,  C07C45/29 ,  C07D301/12

摘要： The invention relates to a process for the oxidation of carbon-containing organic compounds where the said compounds have at least one bond with a bond order >1, wherein an oxidizing of these carbon-containing organic compounds to be oxidized is performed with electrochemically generated C—O—O oxidizing agents, in particular peroxodicarbonate. Also described is the use of C—O—O oxidizing agents generated electrochemically from carbonate, in particular peroxodicarbonate, as oxidizing agents for the oxidation of carbon-containing organic compounds, in particular carbon-containing organic compounds where the said compounds have at least one bond with a bond order >1. Finally, an arrangement for the oxidation of carbon-containing organic compounds is provided, comprising a first unit for the electrochemical preparation of C—O—O oxidizing agents generated electrochemically from carbonate, in particular peroxodicarbonate, and a second unit for the oxidizing of the carbon-containing organic compound with the C—O—O oxidizing agent generated electrochemically from carbonate, in particular peroxodicarbonate. In this case, these two units are connected to one another in such a way that an ex situ generated oxidizing agent can be fed to the second unit.

公开(公告)号：US20220009897A1

公开(公告)日：2022-01-13

申请号：US17296210

申请日：2020-04-14

申请人： DALIAN UNIVERSITY OF TECHNOLOGY ,  DALIAN QIYUAN TECHNOLOGY CO., LTD.

发明人： Hongchen GUO ,  Quanren ZHU ,  Cuilan MIAO

IPC分类号： C07D301/12 ,  B01J29/89 ,  B01J37/10 ,  B01J37/08 ,  B01J37/04 ,  B01J37/06 ,  B01J37/00 ,  B01J35/02 ,  B01J8/18

摘要： A fluidized reaction method for synthesizing propylene oxide by gas phase epoxidation of propylene and hydrogen peroxide relates to a microspherical alkali metal ion modified titanium silicalite zeolite TS-1 catalyst applicable to the reaction method, and a preparation method thereof. A gas-solid phase fluidized epoxidation method refers to a gas phase epoxidation method in which the raw materials of propylene and hydrogen peroxide are directly mixed in the gas phase under normal pressure and temperature above 100° C. and the feed gas enables the titanium silicalite zeolite TS-1 catalyst to be fluidized in an epoxidation reactor. A catalyst applicable to the reaction method is a microspherical alkali metal ion modified titanium silicalite zeolite TS-1 catalyst which has the main characteristic that alkali metal cations are reserved on the titanium silicalite zeolite.

公开(公告)号：US11180467B2

公开(公告)日：2021-11-23

申请号：US16500313

申请日：2018-04-13

申请人： BASF SE

发明人： Nicolai Tonio Woerz ,  Ulrich Mueller ,  Andrei-Nicolae Parvulescu ,  Dominic Riedel ,  Marvin Kramp ,  Daniel Urbanczyk ,  Ulrike Wegerle ,  Christian Mueller ,  Bernd Metzen ,  Markus Weber ,  Joaquim Henrique Teles

IPC分类号： C07D301/32 ,  C07D301/19 ,  C07D301/12

摘要： The invention relates to a process for preparing propylene oxide, comprising (i) providing a stream comprising propene, propane, hydrogen peroxide or a source of hydrogen peroxide, water, and an organic solvent; (ii) passing the liquid feed stream provided in (i) into an epoxidation zone comprising an epoxidation catalyst comprising a titanium zeolite, and subjecting the liquid feed stream to epoxidation reaction conditions in the epoxidation zone, obtaining a reaction mixture comprising propene, propane, propylene oxide, water, and the organic solvent; (iii) removing an effluent stream from the epoxidation zone, the effluent stream comprising propene, propane, propylene oxide, water, and the organic solvent; (iv) separating propene and propane from the effluent stream by distillation, comprising subjecting the effluent stream to distillation conditions in a distillation unit, obtaining a gaseous stream (S1) which is enriched in propene and propane compared to the effluent stream subjected to distillation conditions, and a liquid bottoms stream (S2) which is enriched in propylene oxide, water and organic solvent compared to the effluent stream subjected to distillation conditions; (v) separating propane from the stream (S1) in a separation zone, comprising subjecting the stream (S1) to washing conditions in a scrubber, wherein a solvent mixture comprising organic solvent and water is added as entraining agent, obtaining a bottoms stream (S3), which comprises organic solvent, water and at least 70 weight-% of the propene comprised in (S1); and a gaseous top stream (S4), which comprises at least 5 weight-% of the propane comprised in stream (S1).

公开(公告)号：US10730846B2

公开(公告)日：2020-08-04

申请号：US15479987

申请日：2017-04-05

申请人： MITSUBISHI CHEMICAL CORPORATION

发明人： Akemi Hosokawa ,  Haruhiko Kusaka

IPC分类号： B01J27/24 ,  B01J23/28 ,  B01J23/30 ,  C07C211/62 ,  C07C211/63 ,  C07D301/03 ,  C07D301/12 ,  C07D303/30 ,  B01J31/02 ,  B01J31/34 ,  C07D303/27 ,  C08G59/02 ,  B01J27/16 ,  B01J35/00 ,  B01J35/12 ,  C07C219/06 ,  C07C219/28 ,  C07D213/04 ,  C08G59/24

摘要： A method of producing an epoxy compound, which comprises reacting hydrogen peroxide with a compound having a carbon-carbon double bond, in the presence of at least one of a tungsten compound and a molybdenum compound; and an onium salt comprising 20 or more carbon atoms and one or more of substituents convertible to a functional group containing an active hydrogen or a salt thereof.

公开(公告)号：US10584106B1

公开(公告)日：2020-03-10

申请号：US16122271

申请日：2018-09-05

申请人： King Abdulaziz University

发明人： Suzan Khayyat

IPC分类号： C07D301/12 ,  C07D303/16 ,  A61P31/10 ,  C07C409/04 ,  C07C407/00

摘要： Epoxides and hydroperoxide compounds having antifungal activities derived from the oxidation linalyl acetate, a major component of lavender oil, are disclosed. Also, disclosed are pharmaceutical composition and methods of treating and protecting a subject from fungal infection.

公开(公告)号：US20190276419A1

公开(公告)日：2019-09-12

申请号：US16302099

申请日：2017-05-11

申请人： EVONIK DEGUSSA GMBH ,  thyssenkrupp Industrial Solutions AG

发明人： Holger WIEDERHOLD ,  David BOLZ ,  Georg Friedrich THIELE

IPC分类号： C07D301/12 ,  C07C5/32

摘要： The integrated process comprises a step a) of dehydrogenating propane providing a stream S1 comprising propane and propene; a step b) of separating stream S1 in at least one rectification column, providing an overhead product stream S2 comprising more than 99% by weight propene, a side stream S3 comprising from 90 to 98% by weight propene and a bottoms product stream S4 enriched in propane; a step c) of reacting propene with hydrogen peroxide in the presence of an epoxidation catalyst using propene in molar excess; and a step d) of separating non-reacted propene and propene oxide from the reaction mixture of step c) providing a propene oxide product and a stream S5 comprising propene and propane; wherein stream S3 is passed to step c), stream S5 is recycled to step b) and stream S4 is recycled to step a).

公开(公告)号：US10399952B2

公开(公告)日：2019-09-03

申请号：US16086309

申请日：2017-03-10

申请人： EVONIK DEGUSSA GMBH ,  THYSSENKRUPP INDUSTRIAL SOLUTIONS AG

发明人： Wolfgang Wöll ,  Marc Brendel ,  Bernd Jaeger ,  Niels Bredemeyer ,  Bärbel Kolbe ,  Norbert Ullrich ,  Maik Bernhard

IPC分类号： B01J8/02 ,  B01J8/06 ,  C07D301/12 ,  C07D301/32 ,  C07D301/36 ,  C07D303/04

摘要： During start-up of a continuous epoxidation of propene with hydrogen peroxide in a methanol solvent with a shaped titanium silicalite catalyst in a tube bundle reactor with a cooling jacket, cooling medium is fed at the rate for full load of the reactor with a constant entry temperature of from 20° C. to 50° C., methanol solvent is fed at a rate of from 50 to 100% for full load of the reactor, hydrogen peroxide is fed at a rate that starts with no more than 10% of the rate for full load and is increased continuously or stepwise to maintain a maximum temperature in the fixed bed of no more than 60° C. and a difference between the maximum temperature in the fixed bed and the cooling medium entry temperature of no more than 20° C., and propene is fed at a rate of from 20 to 100% of the rate for full load, increasing the feeding rate when the molar ratio of propene to hydrogen peroxide reaches the molar ratio for full load.