公开(公告)号：WO2023069985A1

公开(公告)日：2023-04-27

申请号：PCT/US2022/078354

申请日：2022-10-19

Applicant: BATTELLE MEMORIAL INSTITUTE

Inventor： TABBAA, Omar P. ,  BARTLING, Craig M. ,  FOWLE, Brett R. ,  FULLERTON, Patrick ,  GEMLER, Bryan ,  HOWLAND, Carrie ,  HUK, Danielle J. ,  SHANK, Zachary R.

IPC: G16B30/10 ,  G16B50/30 ,  G16B99/00

Abstract: Technologies for identifying genetic engineering proteins, organisms, and context signatures include a computing device that may be in communication with multiple client devices. The technologies include receiving a query sequence for a biological specimen, determining an alignment of the query sequence for regions of interest, and determining whether a match exists upstream or downstream from the region of interest in a predetermined database of genetic engineering context signatures. The search range may be predetermined based on each context signature. The technologies further include determining an alignment of the query sequence against a predetermined database of sequences indicative of genetic engineering, and determining whether a similarity score of the alignment exceeds a predetermined threshold. The database may include a genetic engineering protein database or a genetic engineering organism database. Other embodiments are described and claimed.