公开(公告)号：WO2021221973A1

公开(公告)日：2021-11-04

申请号：PCT/US2021/028361

申请日：2021-04-21

申请人： TICONA LLC

发明人： KIM, Young Shin ,  CANO, Camilo

IPC分类号： A61M37/00 ,  A61K9/00 ,  A61K47/38 ,  A61M5/158 ,  A61B5/14532 ,  A61K39/215 ,  A61M2037/0023 ,  A61M2037/0061 ,  A61M2202/30 ,  A61M37/0015 ,  B82Y30/00 ,  B82Y35/00 ,  B82Y5/00 ,  C08K3/346 ,  C08L27/18 ,  C09K19/3838 ,  G01N33/49

摘要： A microneedle assembly that is capable of transdermal delivery of a drug compound, such as a vaccine, (e.g., vaccine) across a dermal barrier of a subject (e.g., human), and/or detecting the presence of an analyte in the subject is provided. The microneedle assembly comprises a plurality of microneedles arranged on a support that each contain a tip and base, one or both of which are formed from a polymer composition that includes a liquid crystalline polymer. By selectively controlling the specific components of the polymer composition, as well as their relative concentration, the resulting microneedles may exhibit a high degree of physical alignment, which can help ensure better performance during use of the microneedle assembly.