摘要:
Detection of spin nucleus resonance (NMR) precession signal/peak of at least one atom or molecule of a sample material placed on a sample electrode while a static uniform magnetic field of a determined strength is induced through it is achieved by applying an alternating bias voltage to a tunneling tip in a frequency at least greater than an NMR frequency range and smaller than a hyperfine electron spin resonance (ESR) frequency range for alternatingly changing within each cycle of the alternating bias voltage at least one atom or molecule of a sample material between diamagnetic and paramagnetic states, and analysing a measured electrical tunneling current passing through the sample electrode. A plurality of hyperfine ESR signals/peaks are identified in the measured electrical tunneling current, each of which associated with a respective cycle of the alternating bias voltage, and a respective hyperfine ESR frequency thereof is determined. At least one single spin NMR precession signal/peak is identified based on changes in the plurality of hyperfine ESR signals/peaks.
摘要:
A microneedle assembly that is capable of transdermal delivery of a drug compound, such as a vaccine, (e.g., vaccine) across a dermal barrier of a subject (e.g., human), and/or detecting the presence of an analyte in the subject is provided. The microneedle assembly comprises a plurality of microneedles arranged on a support that each contain a tip and base, one or both of which are formed from a polymer composition that includes a liquid crystalline polymer. By selectively controlling the specific components of the polymer composition, as well as their relative concentration, the resulting microneedles may exhibit a high degree of physical alignment, which can help ensure better performance during use of the microneedle assembly.
摘要:
A method of using at least one nanoparticle for an anti-counterfeit application including selecting the at least one nanoparticle having a non-spherical configuration; providing the at least one nanoparticle on a substrate; providing a light to the at least one nanoparticle; determining a position of the at least one nanoparticle based on providing the light to the at least one nanoparticle; determining a color of the at least one nanoparticle based on providing the light to the at least one nanoparticle; defining a nanofingerprint based on the position and the color of the at least one nanoparticle; and recognizing the nanofingerprint.
摘要:
The present invention relates to a sensing system that, in a preferred embodiment, can be readily integrated into load-lifting structures (such as wings and landing gears) to provide real-time DPHM and obviate/mitigate catastrophic problems. Broadly, the present sensing system combines at least one shim portion with at least one nanogenerator such as a TENG or a PENG. A major advantage of the present sensing system is that it combines in a single structure the following functions: (a) gap management in the component in which the sensing system is installed, (b) collection/storage of measured data for the component in which the sensing system is installed, (c) harvesting/storing energy from operation environment of the component in which the sensing system is installed (e.g., DPHM data when the present sensing system is used for assessment of an aircraft's structural conditions), and (d) wireless transmission of measured data for the component in which the sensing system is installed to a user interface.
摘要:
The present invention relates to a common-path interferometric scattering imaging system and a method of using such a system, where the system comprises: - illuminating means for emitting an illumination beam (L 0 ); - light collecting means for collecting through a common collection optical path: - a scattered beam (L s ) provided by the light scattering on an object (T) of the illumination beam (L 0 ); and - a reference beam (L r ) provided by the reflection on or transmission through an interface (I) of the illumination beam (L 0 ); - image sensing means (D) for receiving and sensing the collected scattered (L s ) and reference (L r ) beams interfering thereon as an interferometric light signal; - attenuation means arranged in the common collection optical path for attenuating the reference beam (L r ) before it arrives at the image sensing means (D); and - processing means (P) to process data corresponding to the interferometric light signal.
摘要:
System and method for optical drift correction uses light from a light source that is reflected from a curved surface of a mirror and detected at photosensitive detectors to detect movements of the mirror with respect to the light source.
摘要:
La présente invention se rapporte à un système de détection électrochimique de molécules d'intérêt de type «signal-on» ainsi qu'à une méthode mettant en œuvre ledit système.
摘要:
The present invention relates to analyte detection devices and methods of using such devices to detect minute quantities of a target analyte in a sample. In particular, the invention provides a method of detecting a target analyte in a sample comprising mixing the sample with a first detection conjugate and a second detection conjugate in solution, wherein the first and second detection conjugates comprise metallic nanostructures coupled to binding partners that are capable of specifically binding to the target analyte if present in the sample to form a complex between the first detection conjugate, the analyte, and the second detection conjugate, wherein a change in an optical signal upon complex formation indicates the presence of the target analyte in the sample. Methods of preparing nanostructures and nanoalloys, as well as nanostructures and nanoalloys conjugated to binding partners, are also described.
摘要:
The present invention relates to sample holders for holding a sample, particularly for an atomic force microscope. Such a sample holder comprising a sample dish (1) comprising a bottom (2), and an opening (3) arranged in said bottom (2) for receiving and holding the sample (15). Furthermore the present invention relates to a sample holder system and to a method for transferring an e.g. biological sample (15) from a biopsy tool (18) to a sample holder.