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    DOSING REGIMENS FOR TREATMENT OF PROLIFERATIVE DISORDERS
    92.
    发明申请
    DOSING REGIMENS FOR TREATMENT OF PROLIFERATIVE DISORDERS 审中-公开

    公开(公告)号：WO2019199469A1

    公开(公告)日：2019-10-17

    申请号：PCT/US2019/024495

    申请日：2019-03-28

    Applicant: SIGNPATH PHARMA, INC.

    Inventor： SORDILLO, Peter

    IPC: A61K31/12 ,  A61K9/127 ,  A61P35/04 ,  A61P35/02 ,  A61P35/00

    Abstract: The present invention includes compositions and methods for treating a proliferative disorder comprising administering a therapeutically effective amount of an liposomal curcumin or curcuminoids to a human subject in need thereof in accordance with a dosing regimen comprising: at least one treatment cycle administering the therapeutically effective amount of the liposomal curcumin or curcuminoids once per week of at least 100 mg/m2 over 8 hours.

    HIGH EFFICIENT DELIVERY OF PLASMID DNA INTO HUMAN AND VERTEBRATE PRIMARY CELLS IN VITRO AND IN VIVO BY NANOCOMPLEXES
    94.
    发明申请
    HIGH EFFICIENT DELIVERY OF PLASMID DNA INTO HUMAN AND VERTEBRATE PRIMARY CELLS IN VITRO AND IN VIVO BY NANOCOMPLEXES 审中-公开

    公开(公告)号：WO2019133190A1

    公开(公告)日：2019-07-04

    申请号：PCT/US2018/063546

    申请日：2018-12-03

    Applicant: TEXAS TECH UNIVERSITY SYSTEM

    Inventor： DOU, Huanyu

    IPC: A61K48/00 ,  A61K47/59 ,  A61K47/69 ,  C12N15/88

    Abstract: The present invention includes synthesis of polyethyleneimine800-EpoxyC8-22 (PEI800-C8-22) lipids, e.g., Polyethyleneimine800-EpoxyC16 (PEI800-C16), PEI12C16, PEI8C16, and PEI4C16 lipids, compositions and methods for transfecting primary leukocytes, myeloid cells, lymphoid cells, monocytes, macrophages and dendritic cells (DC)comprising a transfection complex comprising: one or more nanoparticles; and Polyethyleneimine800-EpoxyC16 (PEI800-C16), PEI12C16, PEI8C16, and PEI4C16 lipids complexed with one or more nucleic acids, such as, e.g., DNA, RNA, nucleic acid vectors, shRNA, miRNA, and RNAi on or about the nanoparticles.

    LEMON GRASS POWDER EXTRACTION FOR DIGESTIVE PROBLEMS, IRRITABLE BOWEL SYNDROME WITH DIARRHEA, ABDOMINAL CRAMPS, AND BLOATING
    96.
    发明申请
    LEMON GRASS POWDER EXTRACTION FOR DIGESTIVE PROBLEMS, IRRITABLE BOWEL SYNDROME WITH DIARRHEA, ABDOMINAL CRAMPS, AND BLOATING 审中-公开

    公开(公告)号：WO2019074663A3

    公开(公告)日：2019-04-18

    申请号：PCT/US2018/052597

    申请日：2018-09-25

    Applicant: BETTER AND BEAUTIFUL HUMANITY RESEARCH, LLC

    Inventor： BADR, Adnan, S.

    IPC: A01N3/00

    Abstract: The present invention includes compositions, methods of making, and methods of treating or reducing digestive problems or symptoms thereof with an improved heat activated lemon grass composition made by a method comprising combining dried lemon grass tea leaves with water; heat activating and extracting active agents in the lemon grass leaves for 35-45 minutes at 90-100°C; separating the lemon grass leaves from the heat activated active agent in solution; vacuum or spray drying the heat activated active agents; and packaging the heat activated active agents for immediate release, wherein the heat activated active agents provide relief in less than 15 minutes from digestive problems.

    SYSTEM AND METHOD FOR DETECTING AND RESPONDING TO TRANSACTION PATTERNS
    98.
    发明申请
    SYSTEM AND METHOD FOR DETECTING AND RESPONDING TO TRANSACTION PATTERNS 审中-公开

    公开(公告)号：WO2019023406A1

    公开(公告)日：2019-01-31

    申请号：PCT/US2018/043792

    申请日：2018-07-25

    Applicant: CLARITY MONEY, INC.

    Inventor： SOUFIANI, Hossein, Azari ,  DELL, Adam ,  JACOBS, Matt ,  SRIVASTAVA, Vishal

    IPC: G06Q20/40 ,  G06Q20/38

    Abstract: A system and method for detecting and responding to transaction patterns includes one or more servers having one or more processors, one or more databases communicably coupled to the one or more servers, and one or more remote devices communicably coupled to the one or more servers. The processor(s) cause the server(s) to: (a) identify one or more time-based patterns in a set of transaction data stored in the one or more databases corresponding to a data pair over a time period using a spectral decomposition of the set of transaction data, (b) classify the identified time-based pattern(s) into at least two pattern categories comprising a recurring transaction and a non-recurring transaction, (c) generate one or more actions for each pattern category, and (d) respond to the identified time-based pattern(s) by causing the one or more remote devices to perform the one or more actions.

    HYPOXIA TRAINING DEVICE
    100.
    发明申请
    HYPOXIA TRAINING DEVICE 审中-公开
    低氧培训设备

    公开(公告)号：WO2017196588A1

    公开(公告)日：2017-11-16

    申请号：PCT/US2017/030634

    申请日：2017-05-02

    Applicant: LYNNTECH, INC.

    Inventor： REEH, Jonathan ,  WAJE, Mahesh ,  KESMEZ, Mehmet ,  SALINAS, Carlos ,  VARUGHESE, Jibi ,  ZBRANEK, John ,  COCKING, Seth ,  BALASUBRAMANIAN, Ashwin ,  TEURMAN, Cory ,  NETHERLAND, James ,  HITCHENS, Geoffrey Duncan

    IPC: A61M16/10 ,  C01B13/02 ,  G09B9/00 ,  A61M16/06

    Abstract: The present invention includes a device for hypoxia training comprising: one or more electrochemical cells each comprising: a cathode and an anode separated by a proton exchange membrane, each of the anode and cathode in communication with an input and an output, wherein the input of the cathode is in fluid communication with ambient air, and wherein the input of the anode is in fluid communication with a source of liquid water; a power supply connected to the one or more electrochemical cells; and a mask in fluid communication with the output from the cathode of the one or more electrochemical cells, wherein oxygen is removed from the ambient air during contact with the cathode when hydrogen ions separated from liquid water by a catalyst on the anode convert oxygen in the ambient air into water.

    Abstract translation: 本发明包括一种用于缺氧训练的装置，其包括：一个或多个电化学电池，每个电化学电池包括：由质子交换膜隔开的阴极和阳极，阳极和阴极中的每一个与输入 和输出端，其中所述阴极的输入端与周围空气流体连通，并且其中所述阳极的输入端与液态水源流体连通; 连接到所述一个或多个电化学电池的电源; 以及与来自所述一个或多个电化学电池的阴极的输出流体连通的掩模，其中当通过所述阳极上的催化剂从液态水中分离出的氢离子将所述阴极中的氧转化为氧时，在与所述阴极接触的过程中， 环境空气进入水中。

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