公开(公告)号：WO2015135981A1

公开(公告)日：2015-09-17

申请号：PCT/EP2015/055054

申请日：2015-03-11

Applicant: MOVOTEC A/S ,  KØBENHAVNS UNIVERSITET

Inventor： WESTERGAARD, Johnny Erik ,  BILDE, Peder Esben

IPC: A61B5/0488 ,  A61B5/11 ,  A61B5/00

CPC classification number: A61B5/4519 ,  A61B5/0488 ,  A61B5/1107 ,  A61B5/1122 ,  A61B5/6831 ,  A61B5/7278 ,  A61B2562/0219

Abstract: A system, an apparatus, and a method for measuring muscle stiffness in a predetermined joint of an individual are provided. The system and apparatus comprises a measuring unit and a processing unit. The measuring unit is configured to be applied to a body segment of the predetermined joint. The processing unit is configured to: receive a plurality of data sets from the at least one measurement device, analyze the plurality of data sets for one or more indications of an elicited stretch reflex, and calculate a muscle stiffness score. The muscle stiffness score is based on at least a difference between a first stiffness and a second stiffness. The first stiffness is determined from the first subset, and the second stiffness is determined from the second subset.

Abstract translation: 提供了一种用于测量个体的预定关节中的肌肉僵硬度的系统，装置和方法。 该系统和装置包括测量单元和处理单元。 测量单元构造成施加到预定接头的主体段。 所述处理单元被配置为：从所述至少一个测量装置接收多个数据集，分析所述多个数据集以获得所引出的拉伸反射的一个或多个指示，并且计算肌肉僵硬度分数。 肌肉刚度分数至少基于第一刚度与第二刚度之间的差异。 从第一子集确定第一刚度，并且从第二子集确定第二刚度。

公开(公告)号：WO2015103335A2

公开(公告)日：2015-07-09

申请号：PCT/US2014/072887

申请日：2014-12-30

Applicant: ALIPHCOM ,  UTTER, Max Everett, II

Inventor： UTTER, Max Everett, II

IPC: A61B5/00 ,  A61B5/11

CPC classification number: A61B5/4842 ,  A61B5/0004 ,  A61B5/002 ,  A61B5/0022 ,  A61B5/01 ,  A61B5/0205 ,  A61B5/02055 ,  A61B5/02405 ,  A61B5/04001 ,  A61B5/0488 ,  A61B5/053 ,  A61B5/0533 ,  A61B5/08 ,  A61B5/1072 ,  A61B5/1107 ,  A61B5/1112 ,  A61B5/1123 ,  A61B5/165 ,  A61B5/4809 ,  A61B5/4812 ,  A61B5/4866 ,  A61B5/681 ,  A61B5/6826 ,  A61B5/6831 ,  A61B5/6843 ,  A61B5/721 ,  A61B5/7275 ,  A61B5/7282 ,  A61B5/742 ,  A61B2503/10 ,  A61B2505/07 ,  G01L1/00 ,  G06F19/00 ,  G06F19/30 ,  G06F19/3481 ,  G16H15/00 ,  G16H40/63

Abstract: A wearable ring (e.g., on a digit of a hand and/or a toe of a foot) may include sensors for generating motion signals in response to a user's body motion, for generating force signals in response to force exerted by a body portion, for generating biometric signals indicative of biometric activity (e.g., heart rate, respiration, arousal), and for generating location signals based on user location. The sensor signals may be processed to monitor parameters that may impact a state of sleep (e.g., time of sleep, quality of sleep, hydration, inflammation, contraction, fatigue, TRHR, accelerometry, arousal of the SNS, etc.). Data derived from processed signals may be presented (e.g., visually, sound, email, text message, tactile, webpage, etc.) in a format (e.g., reports, notifications, coaching, avoidance, mood) used to improve state of sleep.

Abstract translation: 可佩戴的环（例如，在手的手指和/或脚趾上）可以包括用于响应于用户的身体运动而生成运动信号的传感器，用于响应于生成力信号 用于生成由身体部分施加的力，用于生成指示生物测定活动（例如，心率，呼吸，唤醒）的生物测量信号，并且用于基于用户位置生成位置信号。 传感器信号可以被处理以监测可能影响睡眠状态（例如，睡眠时间，睡眠质量，水合作用，炎症，收缩，疲劳，TRHR，加速度测定，SNS唤醒等）的参数。 可以以用于改善睡眠状态的格式（例如，报告，通知，指导，避免，情绪）呈现从处理的信号导出的数据（例如，视觉，声音，电子邮件，文本消息，触觉，网页等）。

公开(公告)号：WO2015097174A2

公开(公告)日：2015-07-02

申请号：PCT/EP2014079041

申请日：2014-12-22

Applicant: RODIERA OLIVÉ JOSÉ JAVIER ,  RGB MEDICAL DEVICES S A ,  FUNDACIÓ EURECAT

Inventor： RODIERA OLIVÉ JOSÉ JAVIER ,  GONZÁLEZ MARTÍNEZ ANTONIO ,  CORRAL HERRANZ FRANCISCO JAVIER ,  RUIZ NOLASCO RICARDO ,  CARENAS ESPINOLA CARLOS ,  DE HARO MARMOLEJO CARMEN ,  RODRÍGUEZ GUTIÉRREZ ROSA ,  CAMÍ CASALS ANTONI ,  CALZADILLA GISBERT FRANCISCO JAVIER ,  LACHARMOISE PAUL DOMINIQUE ,  COT CANTÓ MARTA

IPC: A61N1/04

CPC classification number: A61B5/1106 ,  A61B5/02233 ,  A61B5/0488 ,  A61B5/05 ,  A61B5/1107 ,  A61B5/4519 ,  A61B5/4836 ,  A61B5/4848 ,  A61B5/6824 ,  A61B5/6828 ,  A61B5/6831 ,  A61B5/7203 ,  A61B5/7275 ,  A61B2505/05 ,  A61B2562/0219 ,  A61B2562/0247 ,  A61N1/0452 ,  A61N1/0484 ,  A61N1/0492 ,  A61N1/0496 ,  A61N1/0556 ,  A61N1/0558 ,  A61N1/36003

Abstract: The present disclosure relates to various methods for determining a neuromuscular blockade status and systems suitable for performing such methods. The present disclosure further relates to electro-stimulation electrodes for stimulating a muscle of a patient, optionally in the context of at least some of the mentioned methods. The present disclosure still further relates to hybrid air-signal connectors for use in an electro-stimulation cuff which can be used in the context of at least some of the cited methods. The present disclosure also relates to electro-stimulation circuits comprising an electrode portion and a track portion suitable for pressure cuffs for electro¬ stimulation, and to pressure cuffs configured to be arranged around a limb of a patient and comprising an active electro-stimulation electrode and a passive electro-stimulation electrode. These electro-stimulation circuits and pressure cuffs may also be used in the context of at least some of the mentioned methods.

Abstract translation: 本公开涉及用于确定神经肌肉阻滞状态的各种方法和适于执行这些方法的系统。 本公开还涉及用于刺激患者肌肉的电刺激电极，任选地在至少一些所述方法的上下文中。 本公开还涉及用于电刺激袖带中的混合空气信号连接器，其可以在至少一些所引用的方法的上下文中使用。 本公开还涉及电刺激电路，其包括电极部分和适于用于电刺激的压力袖带的轨道部分，以及构造成围绕患者肢体布置的压力袖带，并且包括活性电刺激电极和 无源电刺激电极。 这些电刺激电路和压力袖口也可以在至少一些所提及的方法的上下文中使用。

公开(公告)号：WO2015089002A1

公开(公告)日：2015-06-18

申请号：PCT/US2014/069192

申请日：2014-12-09

Applicant: MEDTRONIC, INC.

Inventor： GILLBERG, Jeffrey ,  GHOSH, Subham

IPC: G06F19/00 ,  A61B5/00 ,  A61B5/0408 ,  A61B5/0402 ,  A61B5/0472 ,  A61B5/11 ,  A61N1/362

CPC classification number: A61N1/3702 ,  A61B5/0402 ,  A61B5/0408 ,  A61B5/04085 ,  A61B5/044 ,  A61B5/0452 ,  A61B5/0472 ,  A61B5/1107 ,  A61B5/6823 ,  A61B5/743 ,  A61N1/3627 ,  A61N1/36507 ,  A61N1/368 ,  G06F19/00 ,  G06F19/3481 ,  G16H20/40 ,  G16H40/63 ,  G16H50/30 ,  G16H50/70

Abstract: Systems, methods, and interfaces are described herein for assisting a user in noninvasive evaluation of patients for cardiac therapy and noninvasive evaluation of cardiac therapy being delivered. The systems, methods, and interfaces may provide graphical representations of cardiac electrical activation times about one or more portions of human anatomy and one or more cardiac health metrics.

公开(公告)号：WO2015086450A1

公开(公告)日：2015-06-18

申请号：PCT/EP2014/076698

申请日：2014-12-05

Applicant: INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM) ,  UNIVERSITÉ VERSAILLES SAINT-QUENTIN-EN-YVELINES ,  UNIVERSITÉ PARIS EST CRÉTEIL VAL DE MARNE ,  ASSISTANCE PUBLIQUE - HOPITAUX DE PARIS

Inventor： LOFASO, Frédéric ,  DESMARAIS, Gilbert ,  LOUIS, Bruno

IPC: A61N2/00 ,  A61B5/08 ,  A61N1/36

CPC classification number: A61B5/4542 ,  A61B5/08 ,  A61B5/1107 ,  A61B5/4836 ,  A61B2562/0247 ,  A61N1/3601

Abstract: An installation (10) for determining twitch mouth pressure (TwPmo) of a patient comprises a mouth pressure sensor (12), a magnetic phrenic nerve stimulation device (14) for stimulating the phrenic nerve of the patient, and a controller (16) for controlling the phrenic nerve stimulation device (14), said controller (16) being connected to the magnetic phrenic nerve stimulation device (14). The controller (16) includes an input terminal (22) for receiving an input electric signal provided by the mouth pressure sensor (12), an output terminal (24), and at least an electronic board. Said electronic board comprises a comparison stage (34) for comparing the input signal with at least one reference value, and a generating stage (36) for generating an output electric control signal to the phrenic nerve stimulation device (14) via the output terminal (24), said output signal being generated on the basis of a comparison performed by the comparison stage (34), the generating stage (36) being distinct from the comparison stage (34).

Abstract translation: 用于确定患者的抽搐口压（TwPmo）的装置（10）包括口压传感器（12），用于刺激患者膈神经的磁膈神经刺激装置（14），以及用于 控制膈神经刺激装置（14），所述控制器（16）连接到磁膈神经刺激装置（14）。 控制器（16）包括用于接收由口压传感器（12）提供的输入电信号的输入端（22），输出端（24）和至少一电子板。 所述电子板包括用于将输入信号与至少一个参考值进行比较的比较级（34）和用于经由输出端（Ⅳ）向膈神经刺激装置（14）产生输出电控制信号的发生级（36） 24），所述输出信号是基于由比较级（34）进行的比较而产生的，所述生成级（36）与所述比较级（34）不同。

公开(公告)号：WO2015077173A1

公开(公告)日：2015-05-28

申请号：PCT/US2014/065891

申请日：2014-11-17

Applicant: PENSLER, Jay

Inventor： PENSLER, Jay

IPC: A61N1/36

CPC classification number: A61N1/36003 ,  A61B5/1107 ,  A61B5/224 ,  A61B5/228 ,  A61B5/4041 ,  A61B5/4519 ,  A61B5/4893 ,  A61N1/0456 ,  A61N1/36014

Abstract: A method for stimulating a facial muscle includes the steps of mapping a facial nerve being connected to the facial muscle, locating the facial muscle in response to the mapping of the facial nerve and stimulating the facial nerve by applying an electrode and stimulating the facial nerve with current. The step of mapping includes the step of applying current to the cheek by an electrode and moving the electrode in response to the reaction of applying current to the cheek.

Abstract translation: 一种用于刺激面部肌肉的方法包括以下步骤：将连接到面部肌肉的面神经绘图，响应于面神经的映射定位面部肌肉，并通过施加电极并刺激面神经以刺激面神经， 当前。 映射步骤包括通过电极施加电流至面颊的步骤，并响应于向脸颊施加电流的反应而移动电极。

公开(公告)号：WO2015036925A1

公开(公告)日：2015-03-19

申请号：PCT/IB2014/064377

申请日：2014-09-10

Applicant: MURATA MANUFACTURING CO., LTD. ,  TURUN YLIOPISTO

Inventor： MERIHEINÄ, Ulf ,  JUPPO, Marika ,  KOIVISTO, Tero ,  PÄNKÄÄLÄ, Mikko ,  SAIRANEN, Kati ,  GRÖNHOLM, Markus

IPC: A61B5/11 ,  A61B5/00 ,  A61B5/046 ,  G01C19/5621

CPC classification number: A61B5/1102 ,  A61B5/046 ,  A61B5/1107 ,  A61B5/1121 ,  A61B5/113 ,  A61B5/6823 ,  A61B5/7246 ,  A61B5/7278 ,  A61B5/7282 ,  A61B5/746 ,  A61B2562/0219 ,  A61B2562/028 ,  G01C19/5783

Abstract: A device that includes a sensor of angular motion configured to obtain an angular ballistograph signal indicative of rotational movement of a chest of a subject. Signal processing means are configured to generate from this angular ballistocardiograph signal measured values of an output parameter, which is indicative of cardiac operation of the subject.

Abstract translation: 一种包括角运动传感器的装置，其构造成获得指示受试者胸部的旋转运动的角度测量仪信号。 信号处理装置被配置为从该角度心圆图仪信号产生指示对象的心脏操作的输出参数的测量值。

公开(公告)号：WO2014168952A3

公开(公告)日：2015-01-08

申请号：PCT/US2014033339

申请日：2014-04-08

Applicant: ZOLL CIRCULATION INC ,  PALAZZOLO JAMES ,  HELKOWSKI RICHARD A ,  FREEMAN GARY A

Inventor： PALAZZOLO JAMES ,  HELKOWSKI RICHARD A ,  FREEMAN GARY A

IPC: A61F7/00 ,  A61B5/00 ,  A61F7/12

CPC classification number: A61F7/12 ,  A61B5/024 ,  A61B5/037 ,  A61B5/04001 ,  A61B5/04017 ,  A61B5/04018 ,  A61B5/0488 ,  A61B5/0816 ,  A61B5/1107 ,  A61B5/1126 ,  A61B5/14542 ,  A61B5/4052 ,  A61B5/4836 ,  A61B5/4866 ,  A61B5/6823 ,  A61B5/6824 ,  A61B5/725 ,  A61B5/746 ,  A61F7/10 ,  A61F2007/0054 ,  A61F2007/0056 ,  A61F2007/0093 ,  A61F2007/126 ,  A61N1/36003 ,  A61N1/36014 ,  A61N1/36017 ,  A61N1/36025 ,  A61N2/006 ,  A61N2/02

Abstract: A method of reducing the likelihood of shivering comprises monitoring at least one physiological characteristic in a human or animal subject to detect preshivering and acting to reduce the likelihood of shivering when preshivering is detected.

Abstract translation: 减少发抖的可能性的方法包括监测人或动物对象中的至少一种生理特征以检测预发作用，并且用于当检测到预发作时降低发抖的可能性。

公开(公告)号：WO2014202829A1

公开(公告)日：2014-12-24

申请号：PCT/FI2014/050477

申请日：2014-06-13

Applicant: TURUN YLIOPISTO

Inventor： KOIVISTO, Tero ,  VALTONEN, Tuomas ,  PÄNKÄÄLÄ, Mikko ,  SAIRANEN, Kati

IPC: A61B5/046 ,  A61B5/11 ,  G01R19/04

CPC classification number: A61B5/1102 ,  A61B5/04525 ,  A61B5/0456 ,  A61B5/046 ,  A61B5/1107 ,  A61B5/6804 ,  A61B5/686 ,  A61B5/6898 ,  A61B5/7275 ,  A61B2562/0219 ,  A61B2562/028

Abstract: An apparatus for determining information indicative of cardiac malfunctions comprises a processing device (602) configured to detect whether the time-trend of a signal indicative of cardiovascular motion manifests an indicative phenomenon where the amplitude of a first heartbeat is greater than the amplitude of a second heartbeat and the temporary heartbeat rate is greater prior to the first heartbeat than prior to the second heartbeat. The processing device is further configured to produce an indicator of cardiac malfunction, e.g. an indicator of atrial fibrillation, in response to a situation in which the indicative phenomenon is detected to be present.

Abstract translation: 用于确定指示心脏功能异常的信息的装置包括处理装置（602），其被配置为检测指示心血管运动的信号的时间趋势是否表现出其中第一心跳的幅度大于第二心跳的幅度的指示现象 在第一次心跳之前，心跳和临时心跳速率比第二次心跳之前更大。 处理装置还被配置成产生心脏功能不良的指示器，例如， 响应于检测到指示性现象存在的情况的心房颤动的指标。

公开(公告)号：WO2014182792A1

公开(公告)日：2014-11-13

申请号：PCT/US2014/037115

申请日：2014-05-07

Applicant: PRESIDENT AND FELLOWS OF HARVARD COLLEGE ,  UNIVERSITY OF MASSACHUSETTS MEDICAL SCHOOL

Inventor： PAYDARFAR, David ,  NIEMI, James ,  ZUZARTE, Ian ,  INDIC, Premananda ,  KNODEL, Crystal ,  OSBORNE, John

IPC: A61B5/08 ,  A61B5/0205

CPC classification number: A61H23/00 ,  A61B5/0205 ,  A61B5/087 ,  A61B5/1107 ,  A61B5/14542 ,  A61B5/14551 ,  A61B5/4818 ,  A61B5/726 ,  A61B5/7275 ,  A61B2503/04 ,  A61B2562/0228 ,  A61B2562/0247 ,  A61B2562/0252 ,  A61B2562/0257 ,  A61B2562/0261 ,  A61H23/0236 ,  A61H2201/0146 ,  A61H2201/1602 ,  A61H2201/1619 ,  A61H2201/1623 ,  A61H2201/1635 ,  A61H2201/164 ,  A61H2201/165 ,  A61H2201/5002 ,  A61H2201/501 ,  A61H2201/5061 ,  A61H2201/5082 ,  A61H2201/5084 ,  A61H2201/5089 ,  A61H2201/5092 ,  A61H2201/5097 ,  A61H2205/065 ,  A61H2205/081 ,  A61H2205/12 ,  A61H2230/065 ,  A61H2230/208 ,  A61H2230/305 ,  A61H2230/405 ,  A61H2230/425 ,  G06F19/00

Abstract: Systems and methods for inhibiting an occurrence of an apneic or hypoxic event are disclosed. Physiological data is received from a subject and analyzed to detect an impending apneic event or an impending hypoxic event. A stimulation is applied to the subject to inhibit occurrence of the impending apneic or hypoxic event after an occurrence of a predetermined condition. The physiological data can include respiratory data, cardiological data, or a com-bination thereof. The analyzing includes use of a point-process model and gross body movement data of the subject. Therapeutic effectiveness of the stimulation is increased by accounting for gross body movements of the patient.

Abstract translation: 公开了抑制呼吸暂停或缺氧事件发生的系统和方法。 从受试者接收生理数据并进行分析以检测即将发生的呼吸暂停事件或即将发生的缺氧事件。 对受试者施加刺激以抑制在发生预定条件后即将发生的呼吸暂停或缺氧事件的发生。 生理数据可以包括呼吸数据，心脏数据或其组合。 分析包括使用点过程模型和主体的主体运动数据。 通过考虑患者的身体总体运动来增加刺激的治疗效果。